Scientists at Yale University and in Grenoble France have succeeded in creating a movie showing the breakup of actin filaments, the thread-like structures inside cells that are crucial to their movement, maintenance and division.
Actin filaments are the muscular workhorses of our cells — pushing on membranes to move cells to the proper location within tissues and applying pressure within the interior to keep all working parts of the cell where they need to be. These filaments do their jobs through a mysterious process of continual splitting and reassembly.
"Enrique De La Cruz, associate professor of molecular biophysics and biochemistry at Yale, and his French colleagues used fluorescent stains of cofilin which enabled them to create movies of this molecular disassembly. They used technology called total internal reflection fluorescence microscopy peer into the inner workings of the cell.
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Yale University: http://www.yale.edu
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