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Press Release
The onset of cognitive decline begins at 45


Thanks to INSERM (Institut national de la sant� et de la recherche m�dicale) for this article.

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cbjones1943
Maps and Phenogroups (MAP)
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Mon, Jan 09, 2012, 11:05 pm CST

1. I'm 68 and have been thinking about these questions a lot as well as scanning my output a lot for signs of deterioration.

2. My cognitive functions (when thinking and/or writing about my main academic specializations) have changed over the past 10 y or so, assuming that I can evaluate the changes ~independently.

3. I don't think I've experienced noticeable memory, vocabulary, or reasoning changes.

4. Verbal fluency has changed not so much in the sense that the word(s) is not in my conscious&aware brain but in the sense that I think it takes longer for the word to be pulled out of its file and translated into speech. I think this must be a problem with some aspects of motor function since I don't use a keyboard efficiently any longer.  Plaques could, of course, be the cause of the deteriorations I've described...unpleasant thought.

5. I guess #4 is directly related to deterioration in my ability to organize a project in my brain. It's not that I don't know what I want to say or, even, how I want to organize it all, but the process of getting there takes much longer and is not as automatic as it once was. Again, I'm pretty certain that the seriousness of this deficit depends on topic.

6. I realize that N= 1 + opinion is not reliable; however, this is a "hot" topic for me, and the thought of an inevitable (?) "tipping point" is not pleasant.

7. IMO Eliot Tucker-Drob  UT Austin  has some very neat data on related topics. The two graphs displayed on his lab page are, by way of thinking about it, compelling.

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