Mass poultry vaccination programmes introduced to combat Salmonella infections have led to a dramatic fall in the number of cases since the late 1990s, according to a researcher at the University of Liverpool.
Salmonella are important food-borne pathogens worldwide, causing diarrhoea, vomiting, nausea, fever and abdominal pain. There are currently around 6 million cases of illness from Salmonella across the EU each year, the majority of which are linked to food items such as eggs, chicken, beef, pork, salad vegetables and dairy products.
Between 1981 and 1991, the number of salmonella infections rose by 170% in the UK, driven primarily by an epidemic of Salmonella Enteritidis which peaked in 1993. A raft of control measures were introduced into the poultry industry including movement restrictions, compulsory slaughter and disinfection procedures, as well as a voluntary industry-led vaccination scheme that began in breeding flocks in 1994 and in laying flocks in 1998.
Legislation requiring compulsory slaughter of poultry infected with Salmonella has now been revoked but the mass vaccination of poultry has continued by those breeders subscribing to the Lion Quality Code of Practice and using the Lion Mark on eggs. The code of practice requires mandatory vaccination of all young hens destined to lay Lion eggs against Salmonella, as well as traceability of hens, eggs and feed, a best-before date stamped on shells and hygiene controls at packing stations. Lion eggs now account for around 85% of the total market.
Sarah O'Brien, Professor of Epidemiology and Zoonoses, from the University's Institute of Infection and Global Health, attributes a dramatic fall in the number of Salmonella cases in humans to this mass vaccination programme in poultry.
Professor O'Brien said: "We have seen a marked decline in the number of incidences of Salmonella infection, shown by two significant studies conducted 10 years apart. These studies found that the number of cases fell from 1.6 cases per 1,000 person years for a study conducted from 1993 to 1996 (1) to 0.2 cases per 1,000 person years for the same study conducted from 2008 to 2009 (2).
"In addition, the number of laboratory-confirmed cases of illness dropped from more than 18,000 in 1993 to just 459 in 2010 (3).
"The nature of public health interventions often means that evaluating their impact is complex as they are often implemented simultaneously. The decrease in laboratory confirmed human cases coincides quite closely with the introduction of vaccination programmes in breeder and laying flocks. It is probable that no single measure contributed to the decline in Salmonella cases but the relationship between vaccination programmes and the reduction in human disease is compelling and suggests these programmes have made a major contribution to improving public health."
1. Tam CC, Rodrigues LC, Viviani L et al. Longitudinal study of infectious intestinal disease in the UK (IID2 study): incidence in the community and presenting to general practice. Gut 2012; 61(1): 69-77.
2. Wheeler JG, Sethi D, Cowden JM et al. Study of infectious intestinal disease in England: rates in the community, presenting to general practice, and reported to national surveillance. The Infectious Intestinal Disease Study Executive. BMJ 1999; 318(7190): 1046-5
3. Laboratory reports of human Salmonella cases in the UK, 1981 to 2010 – Health Protection Agency; Health Protection Scotland; Public Health Agency of Northern Ireland
University of Liverpool: http://www.liv.ac.uk
This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.
With funding from the Defense Department, scientists have begun work on devices that would use electric pulses to realign a memory process gone awry
On Friday, the Food and Drug Administration released a vital set of numbers about the routine use of antibiotics …
Side order of veg with that mammoth leg? The Neanderthal diet was probably more varied than we think – using vegetables, herbs and different cooking techniques
An exoskeleton that enables movement and provides tactile feedback has helped eight paralysed people regain sensation and move previously paralysed muscles
A female western gray whale set a new record swimming from Russia to Mexico and back, a total of 13,988 miles, in 172 days
Scientists operating a remote-controlled vehicle about 2,000 feet below water get a rare glimpse of a sperm whale. CBSN's Vladimir Duthiers and Elaine Quijano report on the video.
According to the experts, "blinking is like a kitty kiss"
Genetic profiling of cancer cells can help guide treatment, but such profiles can be ambiguous. Results would be more accurate if all labs tested normal cells from each patient, too.
Researchers in Kenya uncover tools dated to 3.3 million years ago, long before the first humans, as we know them, walked the Earth.
Researchers are facing up to methodological flaws that plague functional magnetic resonance imaging, but the interpretative problems might be harder to solve