Mass poultry vaccination programmes introduced to combat Salmonella infections have led to a dramatic fall in the number of cases since the late 1990s, according to a researcher at the University of Liverpool.
Salmonella are important food-borne pathogens worldwide, causing diarrhoea, vomiting, nausea, fever and abdominal pain. There are currently around 6 million cases of illness from Salmonella across the EU each year, the majority of which are linked to food items such as eggs, chicken, beef, pork, salad vegetables and dairy products.
Between 1981 and 1991, the number of salmonella infections rose by 170% in the UK, driven primarily by an epidemic of Salmonella Enteritidis which peaked in 1993. A raft of control measures were introduced into the poultry industry including movement restrictions, compulsory slaughter and disinfection procedures, as well as a voluntary industry-led vaccination scheme that began in breeding flocks in 1994 and in laying flocks in 1998.
Legislation requiring compulsory slaughter of poultry infected with Salmonella has now been revoked but the mass vaccination of poultry has continued by those breeders subscribing to the Lion Quality Code of Practice and using the Lion Mark on eggs. The code of practice requires mandatory vaccination of all young hens destined to lay Lion eggs against Salmonella, as well as traceability of hens, eggs and feed, a best-before date stamped on shells and hygiene controls at packing stations. Lion eggs now account for around 85% of the total market.
Sarah O'Brien, Professor of Epidemiology and Zoonoses, from the University's Institute of Infection and Global Health, attributes a dramatic fall in the number of Salmonella cases in humans to this mass vaccination programme in poultry.
Professor O'Brien said: "We have seen a marked decline in the number of incidences of Salmonella infection, shown by two significant studies conducted 10 years apart. These studies found that the number of cases fell from 1.6 cases per 1,000 person years for a study conducted from 1993 to 1996 (1) to 0.2 cases per 1,000 person years for the same study conducted from 2008 to 2009 (2).
"In addition, the number of laboratory-confirmed cases of illness dropped from more than 18,000 in 1993 to just 459 in 2010 (3).
"The nature of public health interventions often means that evaluating their impact is complex as they are often implemented simultaneously. The decrease in laboratory confirmed human cases coincides quite closely with the introduction of vaccination programmes in breeder and laying flocks. It is probable that no single measure contributed to the decline in Salmonella cases but the relationship between vaccination programmes and the reduction in human disease is compelling and suggests these programmes have made a major contribution to improving public health."
1. Tam CC, Rodrigues LC, Viviani L et al. Longitudinal study of infectious intestinal disease in the UK (IID2 study): incidence in the community and presenting to general practice. Gut 2012; 61(1): 69-77.
2. Wheeler JG, Sethi D, Cowden JM et al. Study of infectious intestinal disease in England: rates in the community, presenting to general practice, and reported to national surveillance. The Infectious Intestinal Disease Study Executive. BMJ 1999; 318(7190): 1046-5
3. Laboratory reports of human Salmonella cases in the UK, 1981 to 2010 – Health Protection Agency; Health Protection Scotland; Public Health Agency of Northern Ireland
University of Liverpool: http://www.liv.ac.uk
This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.
When amnesia strikes, people can forget everything about their life, including their name. But what causes memory loss? And what happens to people who lose themselves for an hour, a few months – or even for ever?
Tooth unearthed by 20-year-old volunteer hailed as major discovery by paleoanthropologist overseeing dig at Arago cave near Tautavel
Autistic children are just as good at reading emotions from the body as those without – they just don't like the closeness that interpreting emotions from faces requires
Individual cells can be made to act like tiny lasers, offering a more accurate way to tag and monitor tumour cells, for example
If you want to know the secret behind the success of Tyrannosaurus rex and its meat-eating dinosaur cousins, look no further than their teeth.
A recent article argued that sexuality is down to choice, not genetics. But the scientific evidence says otherwise, and points to a strong biological origin
When I hear the word “sabertooth”, my mind immediately jumps to the great sabercats who sliced through throats …
The Portland Press Herald reports that "Captain Eli," a rare orange lobster, will be kept at the Fisherman's Catch Café in Raymond, Maine, before Bill Coppersmith releases it back into the ocean.
A very rare genetic mutation causes some people to develop Alzheimer's in their 30s. It also makes these people the ideal candidates for tests of potential Alzheimer's drugs.
Adding pigment may shield eggs from UV radiation