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Post Archive
2019 (0)2010 (241)
December (20)

Have a little personality on Friday...
Friday, December 10, 2010

Thursday is going to be epic...
Thursday, December 9, 2010

Good Night, and Good Luck
Wednesday, December 8, 2010

Ask Genomic RepairMom...Child Birth
Wednesday, December 8, 2010

Wednesday is definitely a rollercoaster
Wednesday, December 8, 2010

12 Months of Blogging Meme
Tuesday, December 7, 2010

LabSpaces Fantasy Football Challenge: Week 13
Tuesday, December 7, 2010

Don't Run Around On A Tuesday
Tuesday, December 7, 2010

A rhetorical question and science fail...
Monday, December 6, 2010

Sue
Monday, December 6, 2010

It definitely doesn't feel like summer...
Monday, December 6, 2010

A Friday Recipe... Stuffed Jalapenos
Friday, December 3, 2010

A Friday morning haiku for you...
Friday, December 3, 2010

Friday better not be your time of dying...
Friday, December 3, 2010

Music Warz--Fuck all you emos--Punk is where its at...
Thursday, December 2, 2010

Is this a sign of things to come...
Thursday, December 2, 2010

Speaking to the next generation...
Thursday, December 2, 2010

Apparently we must have used hypocritical evangelical coders...
Thursday, December 2, 2010

Have an Unbelievable Thursday
Wednesday, December 1, 2010

Don't ge a Gigolo on Wednesday, its just not right.
Wednesday, December 1, 2010
November (44)

LabSpaces Fantasy Football Challenge: Week 12
Tuesday, November 30, 2010

It Might Get Loud On Tuesday
Tuesday, November 30, 2010

Do you know what the Spellcheck button is?
Tuesday, November 30, 2010

Update: I think I'm dying...Science in Motion...
Monday, November 29, 2010

Feel The Noise On a Monday
Monday, November 29, 2010

The jail story...
Wednesday, November 24, 2010

Don't be talking that shit on a Wednesday..
Wednesday, November 24, 2010

The dark danger and human cost of drug development
Tuesday, November 23, 2010

LabSpaces Fantasy Football Challenge: Week 11
Tuesday, November 23, 2010

Thrift Store T Shirt Tuesday
Tuesday, November 23, 2010

Request for Reprint...Should I put on my throwback jersey too?
Monday, November 22, 2010

Moving Boxes, we aren't going a damn place...
Monday, November 22, 2010

Does your brain feel like its going to Pop on a Monday?
Monday, November 22, 2010

Friday Wrap-Up and Links
Friday, November 19, 2010

Believe Me, Its Friday
Friday, November 19, 2010

An Open Letter To The Guy Who Tried To Mug Me...
Thursday, November 18, 2010

Who the hell said it was Thursday?
Thursday, November 18, 2010

Ask Genomic RepairMom...Retractions.
Wednesday, November 17, 2010

Are you in the house?
Wednesday, November 17, 2010

Pay me fuckers
Tuesday, November 16, 2010

LabSpaces Fantasy Football Challenge: Week 10
Tuesday, November 16, 2010

Don't Feed the Animals
Tuesday, November 16, 2010

A Tuesday Morning Book Review...
Tuesday, November 16, 2010

On which I make my return
Monday, November 15, 2010

One of the best discussions on Climate Change...Ever.
Monday, November 15, 2010

Guess who's back?
Monday, November 15, 2010

Lets keep on Rocking on a Friday...
Friday, November 12, 2010

Don't Rock the Boat on a Thursday
Thursday, November 11, 2010

Don't get too Hooked on Wednesday
Wednesday, November 10, 2010

Don't Wine on a Tuesday
Tuesday, November 9, 2010

Caribbean Monday
Monday, November 8, 2010

I'm out...
Monday, November 8, 2010

We call this a teachable moment...
Friday, November 5, 2010

Can't help that its Friday
Friday, November 5, 2010

A comparative study on pain medication reactions (n=2)
Thursday, November 4, 2010

Dear students applying for fellowships...
Thursday, November 4, 2010

Don't be Tempted on a Thursday...
Thursday, November 4, 2010

Ask Genomic RepairMom...Elections
Wednesday, November 3, 2010

Working it out from home on Wednesday...
Wednesday, November 3, 2010

LabSpaces Fantasy Football: Week 8
Tuesday, November 2, 2010

Hope you find Satisfaction on a Tuesday...
Tuesday, November 2, 2010

Tales of the Genomic Repairman: DNS
Monday, November 1, 2010

The fall of Agamemnon and the rise of Ajax: Is the PI being cheap?
Monday, November 1, 2010

Don't be Trippin on a Monday...unless you want to.
Monday, November 1, 2010
October (47)

Is the PI being cheap?
Friday, October 29, 2010

Friday Save
Friday, October 29, 2010

Nobel Prize Blunder...
Thursday, October 28, 2010

Don't be gray on a Thursday...
Thursday, October 28, 2010

Be a Wiz on a Wednesday
Wednesday, October 27, 2010

Ask Genomic RepairMom.... Vaccines
Tuesday, October 26, 2010

Things learned from my Society meeting...
Tuesday, October 26, 2010

LabSpaces Fantasy Football: Week 7
Tuesday, October 26, 2010

Attack my Site...I'm Gonna Knock You Out...
Tuesday, October 26, 2010

Write, write, write...
Monday, October 25, 2010

Hold on I'm Coming to play you some music on a Monday...
Monday, October 25, 2010

Get off this Friday...
Friday, October 22, 2010

Dear Graduate Student, let me list the reasons why I shall beat you with a stick...
Thursday, October 21, 2010

Slow down, you don't have to Run on a Thursday...
Thursday, October 21, 2010

Could you be loved on a Wednesday...
Wednesday, October 20, 2010

Ask Genomic RepairMom...Big Bang Theory...
Wednesday, October 20, 2010

It was only a matter of time before I got off my ass...
Tuesday, October 19, 2010

LabSpaces Fantasy Football: Week 6
Tuesday, October 19, 2010

Is Everything Zen on a Tuesday?
Tuesday, October 19, 2010

10 Commandments of Poster Presentations...
Tuesday, October 19, 2010

Shout it out on Monday
Monday, October 18, 2010

Pinch me its Friday...
Friday, October 15, 2010

Donor's Choose: Give me your lunchmoney!
Thursday, October 14, 2010

So I know I slagged off on a vendor but now its time to give one props...
Thursday, October 14, 2010

Did you see Fireflies on a Thursday?
Thursday, October 14, 2010

New Series: Ask Genomic RepairMom...Stem Cells
Wednesday, October 13, 2010

Make Wednesday A Magic Moment...
Wednesday, October 13, 2010

The Tribe of Science loses a Warrior
Tuesday, October 12, 2010

LabSpaces Fantasy Football: Week 5
Tuesday, October 12, 2010

Hey Man, quit Ramblin on a Tuesday
Tuesday, October 12, 2010

Cocaine is not a good way to start the week off...
Monday, October 11, 2010

Candidacy Exam: Last one out gets the lights...
Monday, October 11, 2010

Who would have ever thought that Gatorade was pro-evolution...
Sunday, October 10, 2010

Candidacy Exam: I think I'm qualified.
Friday, October 8, 2010

Giving you guys some culture...One Semester of Spanish, Spanish Love Song
Friday, October 8, 2010

I'm sorta Research Blogging...Insight into the function of PALB2
Thursday, October 7, 2010

Chances Are I'm bringing you old guy radio today
Thursday, October 7, 2010

You only knew it was a matter of time before I went off again...
Wednesday, October 6, 2010

Welcome to Wednesday
Wednesday, October 6, 2010

LabSpaces Fantasy Football: Week 4
Tuesday, October 5, 2010

What I'd be doing, if I wasn't doing this: A fishing story!
Tuesday, October 5, 2010

Keep Moving on Tuesday
Tuesday, October 5, 2010

A little Dave Holland recommendation for Tideliar
Monday, October 4, 2010

My mom reads my blog, Happy Birthday Genomic RepairMom
Monday, October 4, 2010

More than a feeling on Monday Morning: I rocked this song in Rock Band
Monday, October 4, 2010

Candidacy Exam: Fourth and inches...
Sunday, October 3, 2010

I'm running late because I got caught on the Radar Gun
Friday, October 1, 2010
September (45)

A man can only take so much bluegrass, time to rock!
Thursday, September 30, 2010

Don't be running down the street hungry as a hound on Wednesday...
Wednesday, September 29, 2010

How not to foster a scientific collaboration...
Tuesday, September 28, 2010

LabSpaces Fantasy Football: Week 3
Tuesday, September 28, 2010

In Spite of Tuesday
Tuesday, September 28, 2010

Candidacy Exam: Someone check his pulse
Monday, September 27, 2010

Stomp it out on a Monday
Monday, September 27, 2010

Update: To the coworker who saw me lose my shit tonight...
Friday, September 24, 2010

Hoping for No Rain on a Friday
Friday, September 24, 2010

Don't have a bad Thursday
Thursday, September 23, 2010

Don't be Greedy, enjoy your Wednesday
Wednesday, September 22, 2010

What is your opinion on reuse of a figure in a journal? Misconduct?
Tuesday, September 21, 2010

LabSpaces Fantasy Football Challenge: Week 2
Tuesday, September 21, 2010

Taking it back old school with The Tokens on a Tuesday
Tuesday, September 21, 2010

I've got a case of the Mondays...
Monday, September 20, 2010

A little Rebel Yell on Monday
Monday, September 20, 2010

An Open Letter to Bio-Rad...This is going to fuck up any chance of a sponsorship...
Sunday, September 19, 2010

A lawyer is calling stem cells outmoded?
Thursday, September 16, 2010

Happy Mexican Independence Day & Potential Darwin Award
Thursday, September 16, 2010

Is Science the Love of Your Life?
Thursday, September 16, 2010

Got it made in the shade on Wednesday?
Wednesday, September 15, 2010

Can you go the distance on Tuesday?
Tuesday, September 14, 2010

LabSpaces Fantasy Football Challenge: Week 1
Monday, September 13, 2010

Candidacy Exam: Damnit go away!
Monday, September 13, 2010

Don't break down on a Monday.
Monday, September 13, 2010

Good grief, its Friday!
Friday, September 10, 2010

Guest Post: The Easy Pub
Thursday, September 9, 2010

You don't know how it feels on a Thursday
Thursday, September 9, 2010

Funniest Comment Contest Part 2
Wednesday, September 8, 2010

Stay with me on a Wednesday
Wednesday, September 8, 2010

I wish I knew: A Tale of 2.5 stories...
Tuesday, September 7, 2010

Lets just be friends on a Tuesday...
Tuesday, September 7, 2010

In case you weren't signed up...
Monday, September 6, 2010

Come on ride that train on a Monday...
Monday, September 6, 2010

Candidacy Exam: Clocks ticking yo!
Monday, September 6, 2010

You want to guest post on LabSpaces?
Friday, September 3, 2010

Watch out for the small print on a Friday
Friday, September 3, 2010

Are you actually working with a neuronal line?
Friday, September 3, 2010

Groups
Thursday, September 2, 2010

Whats that smell and how should I mentor it?
Thursday, September 2, 2010

Travelling Riverside on a Thursday
Thursday, September 2, 2010

LFG...
Wednesday, September 1, 2010

Contest Winners!!!
Wednesday, September 1, 2010

Go Your Separate Ways on a Wednesday
Wednesday, September 1, 2010

My first (and best ever) conference...
Wednesday, September 1, 2010
August (75)

Mentoring a mentor?: Get it in writing.
Tuesday, August 31, 2010

Warning: Its Tuesday
Tuesday, August 31, 2010

I've survived a month of blogging.
Monday, August 30, 2010

New Yorker Article on Francis Collins and the Stem Cell Ruling
Monday, August 30, 2010

Crunch!
Monday, August 30, 2010

Can't Relate to a Monday
Monday, August 30, 2010

Female Science Bloggers...
Monday, August 30, 2010

Potential blogger drink err meet up?
Friday, August 27, 2010

Candidacy Exam: Scheduling, scheduling, scheduling
Friday, August 27, 2010

Friday morning special...
Friday, August 27, 2010

Dear IACUC inspector...
Thursday, August 26, 2010

The State of My Blog
Thursday, August 26, 2010

The Genomic Repairman's Book Club
Thursday, August 26, 2010

Wishing you were home on a Thursday
Thursday, August 26, 2010

Here is where you get to win the liquor
Wednesday, August 25, 2010

Epic Fail on a macroscale level.
Wednesday, August 25, 2010

Some recent big news in the DNA Repair field
Wednesday, August 25, 2010

Don't get caught asleep at the wheel on a Wednesday morning
Wednesday, August 25, 2010

Funniest comment, formerly most obnoxious contest...
Tuesday, August 24, 2010

Dear Trainee, the clock is ticking...
Tuesday, August 24, 2010

Cleanliness is next to...
Tuesday, August 24, 2010

Tuesday morning got you feeling numb
Tuesday, August 24, 2010

An Open Letter to Core Director
Monday, August 23, 2010

Conference Calls
Monday, August 23, 2010

Don't be blue on a Monday!
Monday, August 23, 2010

LabSpaces NFL Pick 'Em Challenge
Friday, August 20, 2010

Its Friday In Spite of Ourselves
Friday, August 20, 2010

The Genomic Repairman gets a pat on the back from the boss and a boot in the ass
Friday, August 20, 2010

Legit Science Question Here Folks
Thursday, August 19, 2010

Rise up on a Thursday Morning
Thursday, August 19, 2010

Dumping on technicians...
Thursday, August 19, 2010

Antibody Naming Contest Winners
Wednesday, August 18, 2010

Trying to find some music for tomorrow, like yesterday
Wednesday, August 18, 2010

ncRNA: Oh the splendor, oh the horror!
Wednesday, August 18, 2010

Still want in on Battle of the Science Blogs
Tuesday, August 17, 2010

Another twofer on a Tuesday morning.
Tuesday, August 17, 2010

Linked Out?
Tuesday, August 17, 2010

Data Embargos
Monday, August 16, 2010

I need a remedy for this sunburn
Monday, August 16, 2010

Cell culture question for the readers...
Monday, August 16, 2010

A letter to the other graduate student in my lab...
Friday, August 13, 2010

Friday morning groovin by the Fratellis
Friday, August 13, 2010

The Apprentice: The Finale!
Friday, August 13, 2010

Candidacy Exam: The Runaround
Thursday, August 12, 2010

Shake off them shoes if you got the Thursday morning blues...
Thursday, August 12, 2010

Update to the aged RO1
Wednesday, August 11, 2010

Candidacy Exam: The Series
Wednesday, August 11, 2010

Shameless product plug
Wednesday, August 11, 2010

Quality is when you...
Wednesday, August 11, 2010

Honestly I didn't think I'd make it to Wednesday
Wednesday, August 11, 2010

A LabSpaces Prayer
Tuesday, August 10, 2010

A two for Tuesday with the boys of Cracker and Camper Van Beethoven
Tuesday, August 10, 2010

You can hold an RO1 for 27 fucking years!
Tuesday, August 10, 2010

Name my antibody!
Monday, August 9, 2010

Antineoplastons? You gotta be kidding me!
Monday, August 9, 2010

Monday morning beats by Morcheeba
Monday, August 9, 2010

So I'm at work today so I figure I owe you a song...
Sunday, August 8, 2010

Well since I'm working on a Saturday
Saturday, August 7, 2010

So I got tagged in a damn meme
Friday, August 6, 2010

What are you doing to promote science to the public?
Friday, August 6, 2010

A chilled tune for Friday and an extra track
Friday, August 6, 2010

Say goodbye to film.
Friday, August 6, 2010

Long Lost Paper
Thursday, August 5, 2010

Feel alive with Live on a Thursday morning.
Thursday, August 5, 2010

A Forum For Discussion
Wednesday, August 4, 2010

Some Wonderful Music for a Wednesday Morning
Wednesday, August 4, 2010

Is this really elevating your science?
Wednesday, August 4, 2010

Helen Larson my ass!
Wednesday, August 4, 2010

2010 LabSpaces NFL Challenge & Banner Contest
Wednesday, August 4, 2010

Balance...You gotta be kidding me.
Tuesday, August 3, 2010

Feeling Stuck on a Tuesday?
Tuesday, August 3, 2010

A Note On Peer Review
Monday, August 2, 2010

Monday Morning Soothing Tunes and Moving Music
Monday, August 2, 2010

Candidacy Exam Blues
Monday, August 2, 2010

How do you balance the job and life?
Monday, August 2, 2010
July (10)
Blogger Profile

Genomic Repairman

The Genomic Repairman is currently a Ph.D. student who escaped from the deep south, and studies DNA damage and repair through biochemical and genetic approaches. He intends to use pine away about his scientific interests and rant about the things (and there are lots of them) that annoy him.

My posts are presented as opinion and commentary and do not represent the views of LabSpaces Productions, LLC, my employer, or my educational institution.

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Awesome Stuff
Views: 257 | Comments: 4
Last by Disgruntled Julie on Aug 12, 2010, 5:46pm
So our program director has already sought me out to tell me that I needed to have all my paperwork in for the exam by next Friday. Turns out he was wrong and that all the forms that were to be signed off on were due over a week ago, thus leaving my grad student status in peril as I am now on probation. Yawn! This means little for me as I got all of the forms taken care of today and will turn in my package tomorrow. I am actually kind of sad to be off probation this soon, I was hoping to get an ankle bracelet for my "work release." I don't have to start my exam right away, my stuff just needed to be turned in by some arbitrary date so that the administrators will be pleased. Apparently, the lack of my documentation has angered the powers at be but I could care less. In the grand scheme of things my shit is ten days late but it means nothing, I mean they take their sweet ass time getting back to me on stuff, so why should I care? Unless its absolutely vital to my existence, it will get done when it gets done. Sadly this is how the administration works, where my stuff will be in before they even get all of them to meet to place me on probation.

But enough about bureaucrats, I spent a solid three hours today chasing down folks for their signatures. To form an . . . More
Views: 200 | Comments: 3
Last by Odyssey on Aug 12, 2010, 7:37am
So I'm taking a beating from my fellow science bloggers right now and probably rightfully so. I understand that there are greybeaded PI's out there still doing kickass science that puts any noob and midcareer scientist to shame. I was more venting about this one PI, whom I am familiar with, and did not mean to generalize this to all senior PI, so my apologies. So I think this weedhopper definitely deserve some whacks from AbelPharmboy's ClueStick. So to Blue Lab Coats, Abel, and JuniorProf thanks for the intellectual lesson and whupping. I deserved it. And to any aggrieved AARP members out there with RO1's my apologies too.
. . . More
Views: 222 | Comments: 2
Last by Genomic Repairman on Aug 11, 2010, 9:32am
So I know I previously posted about my candidacy exam blues but reality hit home today when my exam committee chair dropped the deadline on me for my topics by next week. So I'm going to try and give regular updates as they pick one of my three off-topics and then I have to write a NIH F32-style postdoc fellowship application. Where this thing gets a little awkward is the preliminary data section, I can use recent papers but I have to make sure that I balance this section and don't leave gaping holes in my background section. I'm pretty sure this is going to be the end of me, but I don't plan on living too long.

*True story: I took a job right after college that offered health and life insurance but you had to get a physical done and when the HR manager asked me what I wanted to do as far as my retirement plan. I told him to screw the 401k, I planned on dying young. Then the HR manager replied, "Then I guess you really aren't too worried about the employee health savings plan or the additional life insurance before what we offer for free?" And I answered, of course, "I just the Big Lebowski-esque coffee can funeral. I don't need Folger's even, the . . . More
Views: 156 | Comments: 5
Last by Thomas Joseph on Aug 12, 2010, 10:25am
Preface: Per FCC regulations I will disclose that I'm not getting paid, nor am I getting free product at AMRESCO. I just fucking hate Ethidium Bromide, the intercalating agent, not the blogger, I dig that chick.

Anywho back on point, as I am one of the lowest on the lab pecking order and having experience as a chemist, I have always had to deal with ethidium bromide and its waste. Generally I have to filter the used buffer with these horrible charcoal filters that have a flow rate of similar to that of an old man with a prostate the size of an NBA game ball. Needless to say it would take days to filter a few liters of used buffer not to mention having to deal with the solid waste from the gels. What was the Genomic Repairman to do?

Is it a bird? Is it a plane? Fuck that, its the UPS guy and he is bring me some EZ-Vision DNA Dye from AMRESCO! This product has been awesome, we don't generate waste, the gels can just go in the normal biohazard and my life has dramatically improved. Oh and here is a tip for the folks trying to do science on the cheap: Their 6X loading dye fluoresces so strong I cut it in half with 50% glycerol and use it as a 5X stock. . . . More
Views: 129 | Comments: 0

can western blot with a 20 year old antibody that your boss has kicking around from their postdoc days and get the cleanest blot you have ever seen. And all the boss can say is, "The shit still works, did you expect anything less from me." My boss is a balla! And somehow I embedded the video from the spanish version of Yahoo!

. . . More
Views: 81 | Comments: 0
Here is a chill song by Cary Brothers whose songs in my opinion are a perfect marriage of lyrics and music.
. . . More
Views: 262 | Comments: 8
Last by Dr. O on Aug 10, 2010, 6:03pm
Our LabSpaces,
who art on the blogosphere,
hallowed be thy bloggers.
The news be splained,
my rage shant be in vain,
as it is in lab.
Give us our daily bandwidth.
Forgive us our trollings,
as we forgive those that troll against us.
And lead us not to news links from Science Daily,
but deliver it from better sources.
For thy link is long,
shorten it on bit.ly,
and post upon Twitter.
Amen.

. . . More
Views: 107 | Comments: 0

Front man David Lowery and drummer Frank Funaro play in the popular alternative band Cracker and its lesser known (and still operating forerunner) Camper Van Beethoven. The first song, "Friends" also features Patterson Hood of the Drive-By Truckers. I love the song because it references Captain Beefheart.

And you gotta love the violin on "Pictures of Matchstick Men" by Camper Van Beethoven.

. . . More
Views: 5485 | Comments: 15
Last by Frances Scientist on Jun 24, 2011, 9:36am
Preface: This is an angry rant.
So I was looking up someone in our field who is a little older, okay they are fucking old. The guy has an RO1 going on year 27, and another younger model RO1 that just turned 26 years old. Each of these grants is in excess of $500k a year in direct total costs, plus the guy has a piece of an PO1 (don't worry this is relatively new). Seriously to have two grants that old, um has there never been a fucking priority shift? Ever? At some point wouldn't the NIH cutoff funding for the grant as this dude has probably drug this shit down the road for way too long. I've seen postdocs from his lab present and its on par with taking a kid who wears a helmet to a debate against William Jennings Bryan (old school reference, look it up, I'm not giving you the damn link). This guy has lost his innovation and does not want to go outside of the box based upon questions posed to him during presentations and comments from many leading PI's in the field. Hey why don't you look at this? No, I prefer to just focus on this. No wonder new researchers can't break into the field, when we have overfunded fucking driftwood sitting at the top. And believe me I am not anti-competition but come the fuck on, 27 years? TV shows en . . . More
Views: 703 | Comments: 11
Last by Genomic Repairman on Aug 09, 2010, 9:41pm
Always wanted to name a new celestial body or uncharted island but could never find one. Me neither. But here is your big chance. I just completed an antibody screening project for some rabbit monoclonal antibodies and now I need to name them. This project was an utter bitch as getting something soluble let alone antigenic was ridiculous. I cannot to tell you what protein they are raised against but currently there are no suitable antibodies that exist to this protein, so this is a pretty sweet. So I'm getting at least 3 subclones from each of my parentals for a total of 9 monoclonal antibodies. This is your chance to come up with something creative and name it to me. So here are some ideas for naming.

If you come up with long convoluted names then give me an abbreviation for it on the tube because its too hard to write BoHonkeyPimpStick (BHPS) or GiantToweringTrannyMakeOutSession (GTTMOS) on an Eppendorf tube is way too hard. So give me your names and I'll let you know who the winners are! I have a slick name up my sleeve but I'm saving it for later. . . . More
Views: 123 | Comments: 4
Last by Genomic Repairman on Aug 09, 2010, 9:42am

Bradley Burgess
So I'm assuming, you haven't heard of Morcheeba, a famous British trip hop band masterminded by the Godfrey brothers. This song also features former construction worker turned strings virtuoso Bradley Burgess.

Enjoy the beats and have a good Monday. . . . More
Views: 74641 | Comments: 123
Last by Brian Krueger, PhD on Jul 18, 2011, 9:15am
So I came across a movie about Stanislaw Burzynski and his controversial antineoplastons treatment. So I'm pretty sure you are scratching your head wondering what an antineoplaston is? Apparently Burzynski created this convoluted phrase to use instead of simply saying, its a peptide. But take it from top here gang. In 1968, Burzynski graduated from medical school at age 24 in Poland, at age ~25 he also received a doctorate in biochemistry, making him one of the country's youngest M.D., Ph.D. Are you kidding me, when did he start his MSTP training program at age 17? The claim to the Ph.D. is slightly dubious as the medical school at that time was not known to grant Ph.D.'s and faculty at the Medical Academy of Lubin report that Burzyinski only did one year of a lab research project while in medical school to receive this mystery doctorate. Also the guy never received any specialized training in cancer or cancer therapeutics. So flash forward to 1973, Burzynski has spent the past three years at Baylor COM working in a lab isolating peptides from rat brains. He receives his license and is able to practice medicine in the US and also gets a three year grant to study urinary peptides effect on t . . . More
Views: 191 | Comments: 6
Last by Odyssey on Aug 10, 2010, 11:22am
So whether you go to church or you don't believe in a heaven, I think we can all agree Stairway to Heaven is one of the best rock and roll songs and has probably the best guitar solo by the man, the myth, the legend, Mr. Jimmy Page.
. . . More
Views: 155 | Comments: 4
Last by Genomic Repairman on Aug 07, 2010, 9:39am
I might as well give you some tunes to push you through the day. The first is the title track to a video game called Borderlands. Enjoy Cage The Elephant.


And since it sucks working on weekend, here is a second one for the mid-day push as you groove on down electric avenue.


Have a great weekend. . . . More
Views: 201 | Comments: 10
Last by Genomic Repairman on Aug 07, 2010, 11:45pm
So Dr. Becca tagged me in some kind of internet meme. And the gist of it is to:
"Sum up your blogging motivation, philosophy and experience in exactly 10 words. "
And of course to pick 10 other people to send this albatross (reference to The Rime of The Ancient Mariner) but the evil stops here folks, but I feel like I should give you two memes for the price of one.

So here is my motivations
"A lab coat doesn't make you a scientist, just cooler."

"Call before you come so I can shave my chacha."
Reference to the song below.
. . . More
Views: 120 | Comments: 5
Last by Genomic Repairman on Aug 08, 2010, 1:08pm
So this was the opening theme to the 1995 movie Hackers, probably the first movie that put Angelina Jolie into the spotlight. Anywho, its a really groovy and relaxing song. Enjoy


And for those of you this weekend that are stuck in the lab, in the office, or just working. Enjoy a little Loverboy.
. . . More
Views: 728 | Comments: 14
Last by Lab Mom on Aug 06, 2010, 9:34pm
So anyone who does immunoblotting, northern, southern, or whatever freaking direction of blotting knows that autoradiography film is quite expensive. Plus silver is precious natural resources and reagents for the developer are not cheap either. In my mind the future will lead to people moving over to molecular imaging whereby you use a camera to detect chemiluminescence. Our lab has made the shift by investing in one of these units, I won't mention which one so that I don't look like some shameless product whore. Opening the box of this thing was awesome, it had that new equipment smell and was like a kid on Christmas Day putting it together.
*This entry contains a YouTube video*
The thing looks like some hulking off-white plastic monolith but its great, it has dual utility with a UV setup to look at gels, white light to take pictures of Coomassie stained gels, as well as its capabilities for westerns. Are far as northerns or probe-labelled gels we use other imaging equipment. I think this is where the field is heading, in order to cut costs and conserve resources. Our only investment is a fluorescent marker to annotate our marker ladders on our blots. Other than that, I add my ECL substrate, toss it in the unit and setup exposure times and walk away. And . . . More
Views: 270 | Comments: 1
Last by Evie on Aug 06, 2010, 6:01pm
So my day to day job is to be a lab chimp who is chained to the bench and crank out data but in our lab we take on an active role in engaging the general public about science. From time to time we have civic groups that come onto campus and PI's usually give them the grand tour of the facilities. My boss being a smart and busy PI, has transferred those duties to myself. So I have given tours to everyone from the American Legion to the Lion's Club to visiting dignitaries. This is actually fun and gives you a chance to wow the public with simple equipment that you use everyday. Also it challenges you to break down your science in layman's terms so that they may understand it and you present the big picture of your research in little words. Not only that its a chance to bone up on your presentation skills and network with folks from the community. I do my best to increase the scientific literacy of the group and get them to understand that we work hard and have to be very methodical to get relevant results that can be of benefit to society. As I say, if you want good science to give you good health outcomes, its going to take time and money. Since I have rocked out with this, I am starting to become the designated tour giver on campus, a situation that is ann . . . More
Views: 284 | Comments: 6
Last by Genomic Repairman on Aug 06, 2010, 9:06am
So my old PI was submitting a manuscript for publication last summer to a good journal (IF ~6.5ish). The paper looks pretty decent and my name is buried somewhere in the middle of the authorship orgy, but shit I'll take any publication to pad my list. I have not heard anything since he showed me the manuscript before submitting it last summer. In that time old PI has been booted out of old department and taken up root in another department in the same campus, and left that department. Last I checked he is not even employed by my old university, which is sad he was a nice guy. But then again nice guys don't always make great scientists. So in the mean time I check Pubmed everyday like a teenage girl hanging around by the phone for some guy to contact her. I've previously tried to contact the guy just to see how things are going in the lab and maybe get a sense of what's going on with the paper and gotten no response. The thought has crossed my mind to email him specifically about the manuscript and see what is going on but now I don't even know where to email him as he has dropped off of the grid. I'm thinking he maybe got rejected and is just shopping it around to get it into another journal. My worst fear is that bossman said fuck it and just thre . . . More
Views: 118 | Comments: 3
Last by Genomic Repairman on Aug 06, 2010, 11:06am


One of my favorites. . . . More
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So Brian has been kind enough to set up a Forum section here at LabSpaces, all you have to do is just look in the upper lefthand corner for it. So far its been pretty blogger heavy, but we want to hear back from you. Everyone of you that reads our blogs or news posts is a consumer and thus we want to give the best possible experience for the consumer. Want a way to unsubscribe from comment notifications, let us know. Don't like my music selections, get it off your chest. You have a cool idea for a next community wide blog theme, preach it to the choir brother. Do you want to take part in the LabSpaces NFL Challenge, I think you are getting the picture. This is your site, we just write stuff here partly for our entertainment but mostly its for you guys. Our goal is to talk about various facets of science and to hopefully make it interesting. So any feedback from you guys just enhances the process and sweetens the product. So in closing, I hope to see you in the forum. Good night and good luck.

*This entry contains a YouTube video* . . . More
Views: 633 | Comments: 0
So if you are a life scientist and you have been hiding underneath a rock you might have missed Rebecca Skloot's bookumentary (as I'm calling it on) history, scientific impact, and ethics of the cells from Henrietta Lacks, commonly referred to as HeLa. Most of us have come into contact with these cells in the lab at some point in our career so this was a great read for me. I definitely think you should take a look at the book and you can borrow my copy if you want to be a member of the Genomic Repairman's book club. Enough about all this talk of the HeLa book, Skloot is making money, now its time for me to make my page views dammit. So in 1997 Adam Curtis with the BBC put out a documentary on the cells entitled The Way of All Flesh. Thanks to digitization you can take a look at documentary broken down into 8 parts on my youtube page or the full cut of the documentary (if you don't mind the load time) from the link here.

Part 1
*This entry contains a YouTube video*

Part 2
*This entry contains a YouTube video*

Part 3
*This entry contains a YouTube video*

Part 4
*This entry . . . More
Views: 236 | Comments: 3
Last by Genomic Repairman on Aug 05, 2010, 1:03am
So we recently got a new department chairman after an extensive search. The person is technically an internal hire but from another department at another facility. Anyways she is a great scientist and mentor and is very trainee-oriented. Her goals for are department were to elevate our standing in the scientific community. And her solution to this was to publish as much as we could in high impact factor journals. Part of me agreed and part of me felt kind of dirty for agreeing with the statement. I don't consider your CNS glamour mag publications to be the end all be all. I understand that folks want to publish in journals with as high of an IF as possible. But I'm not going to look at someone with a JBC publication and say you aren't shit unless you publish in PNAS. Besides it takes extra time, work, and luck to publish in the scientific journal equivalent of Mount Olympus. Recently I saw a poll on whether to spend a 3 year postdoc and get 1 midtier publication or a 6 year publication with a glamour mag publication. I chose for the former. Especially as getting published in a glamour mag doesn't always mean your science is better it could maybe be a better reflection of a hot field or your boss's track record of publishing there. Although I . . . More
Views: 141 | Comments: 3
Last by Suzy on Aug 04, 2010, 11:25pm
So after everyone posted/vented about their worklife drama, how about you kick back sitting on the dock of the bay watching the tide roll away...
. . . More
Views: 113 | Comments: 4
Last by Dr. O on Aug 05, 2010, 1:31pm
Are you a fan of fantasy football? Have you ever thought about playing? Do you like to shit talk? Well then my friends I have a proposition for you. I have created a fantasy football league that is pretty rudimentary. You just pick the team that you think will cover the points spread. No picking a defense or wondering which wide receiver to sit this week. Just pick em and forget em. I got a fair amount of the bloggers (B-rizzle Krueger, Biochem Belle, Lady Scientist, Jade Ed) here signed up to play but I'd also like to get some more readers to play too. So if you are interested shoot me a message and get ya all fixed up. We will be awarding a weekly prize in the form of a banner to display that goes to the person with the most points each week. I haven't designed a banner yet so if anyone wants to do it, let me know. We can have a contest for the best banner. The winner of the banner contest will get some free booze of my choice (don't worry nothing cheap) shipped to them. And if you are going to come with a banner come strong, don't bring some weak-ass WordArt into this house, you'll just embarrass the family. Also I'll send the challenge winner (the person with the most overall points) some booze and maybe a Labspaces T-shirt once we . . . More
Views: 1020 | Comments: 19
Last by Genomic Repairman on Aug 03, 2010, 10:30pm
So recently my personal life has been fucking turbulent to say the least. I think maybe the biggest issue for us in science (besides the horrible jobs and funding situation) is or ability to balance our home life and our work life. Do I think balance can be achieved? Yes, but not at any one point in time. Lets face it we can't give 50% to work and 50% to life constantly as one noted scientist once told me. You will constantly be out of balance. But the goal is not to let the scale tilt too far to one side for too long. Unfortunately for me, mine has probably been welded down to the work side for quite a while. And it has for the following reasons:
-Mentoring two students
-Antibody screening for two different projects
-Making stable knockdown cell lines
-Making overexpressing cell lines
-Prepping for candidacy exam
-Submitting fellowship application
-Trying to work on a review article

So when work builds up, I tend to act less human and more like a robot and just grind away. And unfortunately I take on a sort of tunnel vision when I'm grinding. This is probably due to my younger days of working on fishing boats to help pay for college where I would grind through the work, weather, and pain to get the job done. If its not directly re . . . More
Views: 87 | Comments: 1
Last by Dr. O on Aug 03, 2010, 5:58pm

Then enjoy "Stuck In The Middle" by the Scottish group Stealers Wheel, if you have ever seen Resevoir Dogs then you know this iconic song. Enjoy . . . More
Views: 290 | Comments: 10
Last by Genomic Repairman on Aug 07, 2010, 9:43am
So Errol Friedberg (a notable dude in the DNA Repair field) put out an editorial in DNA Repair a few months ago talking about peer review of scientific papers. He brought up some great points listed by one of the international conferences on biomedical literature peer review. I know we gripe about the third reviewer so I thought I would let you see the points that Friedberg raises:
1. Blinding reviewers to authors identity is not useful
2. There is no association between authors signing their reviews and the quality of the review
3. Passing reviewers comments to co-reviewers has no obvious effect on the quality of review
4. reviewers aged under 40--write reviews of slightly better quality
5. Appreciable bias and parochialism exists in the review system
6. There is a huge challenge in developing a useful instrument to measure manuscript quality

Link to article below:
http://www.ncbi.nlm.nih.gov/pubmed/20378420

Discuss amongst yourselves! . . . More
Views: 297 | Comments: 4
Last by Genomic Repairman on Aug 02, 2010, 1:28pm

This one is by Colin Hay, formerly of Men at Work (think Land Down Under). The youtube embed below is for him singing the song in an episode of Scrubs. Check this one out to see what happens to his guitar at the end of the song. Also note that tunage will probably be moving from the blogs section of Labspaces to another part so that you can get your morning fix of music and we can keep the blog section scientifically oriented, which really is how it should be. Enjoy.
. . . More
Views: 267 | Comments: 10
Last by Brian Krueger, PhD on Aug 02, 2010, 10:58pm
So I just finished the second year of my Ph.D. program. Yay for me, no more classes no more books, no more drunken hungover looks! The bad news is that I have to take a qualifying exam to progress onto my Ph.D. candidacy. This topic involves an off topic exam whereby we present our examination committee members (n=4) with three topics that are not related to our current or previous work. You have to prepare an postdoctoral fellowship application in the NIH F32 style. I have one topic nailed down and now I need to gather two more. My approach to gathering these topics has been to power through a ton of reviews, mainly from the Nature family (Nat Rev Can, Mol Biol, etc.). These reviews do a great job of giving you the historical background, current landscape of the research topic, and some pressing issues that need to be sorted out. The plan is to blog about this throughout the process and I'll do my damnedest to give regular updates. While its going to be a royal pain to create an original proposal from scratch in just a month, it will be a great test of my skills. So if you have any great topics kicking around that might be interesting, let me know and I'll take a gander at them.

And not to leave you without some tunes and to tie into the blues theme, . . . More
Views: 186 | Comments: 0

Balance?
So some of the bloggers on Labspaces are going to be posting about our work life balance and the difficulties involved in this topic that affect us all. I think this is going to be awesome as you will get a little insight into each of our lives and see how we try to balance our professional and personal lives respective to where we are at in our career journey. Any input or tips you folks can share would be awesome and greatly appreciated.

And since we are all Under Pressure, why not cue the music.
. . . More
Views: 828 | Comments: 6
Last by Genomic Repairman on Aug 01, 2010, 4:55pm

Here is a sample of music that I jam out to when doing plasmid preps in the lab. Hit me back with something else to add to the list.

-"Play That Funky Music", Wild Cherry
-"Superstitious", Stevie Wonder
-"Run", Snow Patrol
-"Stay with me", The Faces
-"Lazybones", Soul Coughing
-"Do Right", Jimmy's Chicken Shack
-"F Word", Babybird (Intro the BBC Show "The F Word" [The one where Ramsay is changing])
-"Run Honey Run", Morcheeba (Featuring Bradley)
-"Hotel California", The Eagles
-"Where the Streets Have No Name", U2
-"Lucky Today", Cloud Cult (The song from the Esurance commercials)
-"Creatures (For A While)", 311
-"Sonic Reducer", Both the original by the Dead Boys and cover by Pearl Jam
-"What Is And What Should Never Be", Freakin Led Zepplin Baby
-"Taking Care of Business", BTO
-"A Little Respect", Erasure
-"Rebel Yell", Billy Idol (acoustic version please!)
-"Lit Up", Buckcherry
-"The Kids Are Not Alright", The Offspring
-"Sheep Go To Heaven", Cake
-"AM Radio", Everclear . . . More
Views: 139 | Comments: 4
Last by Genomic Repairman on Jul 30, 2010, 7:57pm
. . . More
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Last by Genomic Repairman on Jul 31, 2010, 4:46pm
What are you guys doing? What is working best? Our lab used to do a joint journal club with another lab group where we met once a week to go over a paper. It was nice to get together with the other lab group that is in our field but works in another subfield. However, what tended to occur was people picked research that was pretty much directly related to their own work. Yawn. I tend to stray out of the box and pick papers away from my topic or stuff that is breaking in the field. For example if I study Granny Smith apples, lets talk about some Asian pears (sounds kind of dirty, but its just a fruit analogy). My other colleauges, they just want to talk about fucking Granny Smith apples. My reasoning for doing this is that what if your subfield falls out of funding graces and you have to switch subfields? Why not at least have a decent grasp of whats going on close to your field. I'm not saying stem cell biologists need to know the intricacies of the lipids biochemistry, but learn whats going on your intellectual neighbors backyard. But enough of the rant, I'll get back on topic. As our lab grew we decided to do a solo journal club with our lab group only and I think we hit on a good model. Everyone picks a paper and we compile the citations onto a paper ha . . . More
Views: 129 | Comments: 0

Hope you enjoy the pairing of Frank Zappa and Captain Beefheart. Zappa played some of the most technically demanding music of his time and recorded over 60 albums and more keep being released from the vault posthumously. This is from the album Hot Rats. I implore you not to buy any Zappa recordings from Itunes, they are of shitty quality and this would not please Zappa. The man put his heart and soul into not only playing high quality music but recording quality as well too. If you are looking to get into Zappa, run to your local music store (or maybe Best Buy) if they do exist and pick it up or a lot of his stuff is available on CD from Amazon. Enjoy the sick guitar solo and some culture. . . . More
Views: 468 | Comments: 3
Last by lifesciencegirl on Jul 30, 2010, 10:16am


Preface: My uni does the whole rotation system where you are required to do three different 10-week rotations. You can wave one of the rotations if you have an M.S., which I took full advantage of.

Lab #1
I loved this lab, it was really good people but also a lot of people. The lab consisted of one technician/lab manager, two instructors, three postdocs, a visiting lecturer, and three other graduate students. The PI was pretty busy and traveled a little bit and there was not much one on one mentorship. Plus the space was cramped, and I mean cramped. I had exactly two linear feet of benchspace to work with. Also the shelves above me were crowded with other shit. Also there was one tissue culture hood, imagine eleven folks trying to share that thing. But the PI was a really nice guy and we stop and speak anytime we meet. His lab was my backup.

Lab #3
Out of order but lets run with it. This is the rotation I did not do. This is a mega-lab, consisting of about twenty some-odd people. The PI did virtually no mentoring, you were only summoned to the office for an inquisition of data or a tune up if you weren't producing quickly enough. The graduate students were behind schedule because they couldn't schedule committee meetings due to the PI's . . . More
Views: 232 | Comments: 5
Last by Suzy on Jul 30, 2010, 1:17am
The Laboratory Manager is a unique position in the lab and a quite stressful one. Lets face it, you take shit from three sides: THE MAN (the PI), the front lines (folks working at the bench in the lab), and THE BUREAUCRACY (accountants, safety folks, HR, etc). So while they are balancing satisfying this week's whim that the PI has a scientific boner for, they are also calling to get the -80 repaired, making sure everyone has their radiation safety training certificates documented, getting PO's to order all the shit you need, and whats that there is an internal audit going on? Hopefully the PI treats the Lab Manager like gold because they are the constant in the lab. Grad students, postdocs, and techs, they come and go, but this person stays with the PI throughout most of their career if not all depending on circumstances. So from a PI's perspective THE MAN wants to keep the Lab Manager happy.

So why should you guys on the front line keep the lab manager happy? Um, maybe because they order all of your stuff, which entails going through mounds of paperwork and red tape. They make sure you have the basic essentials in the lab and all the stuff in the lab is working. I have had the misfortune to spend six months working for a horrible lab ma . . . More
Views: 127 | Comments: 2
Last by Genomic Repairman on Jul 29, 2010, 10:37am


This song is one of the reasons why I have been tossed out of a bar like thirty times (underage drinking being the main culprit, but I'll post on that later). I evolved into druankasaurus rex and began dancing to the song on top of table. It was shameful and thank goodness the video evidence has largely been destroyed of this event. How does this relate to science. Run the fucking p value, I'm guessing once out of 30 times is probably p . . . More
Views: 193 | Comments: 2
Last by Genomic Repairman on Jul 28, 2010, 9:27pm
First I'll give you the contents of the note and then explain the situation.

"Dear Genomic Repairman,
Thank you for taking time out of your day to teach me about your profession. I really enjoyed the learning experience, and greatly appreciate your effort. I'm sorry if it came off as if I wasn't paying attention or was uninterested, when in truth I was quite fascinated. Once again, than you for allowing me to shadow under you..
Signed
Teenage Girl"

So we had some high school students come in for the afternoon and shadow some scientists at my institution. I received a pair of high school freshmen and took them to our lab. I let them get a little hands on and help me with a western blot and explained to them that we were looking for levels of specific proteins and taught them a little about the concept. However, these two girls did not give a fuck. They were more engrossed in talking about who was a bitch, what guy had dreamy eyes and how come blah blah blah insert random asshole's name did not call them back. They were more intent on dicking around on their iPhones than to put on a pair of gloves and helpt set up a transfer or develop an immunoblot. Getting these two to stop talking and focus on doing a little something was on par with a quadriplegic scaling . . . More
Views: 578 | Comments: 5
Last by biochem belle on Aug 02, 2010, 8:23am
So in case you missed it. My motherfucking man, Harold Varmus, aka NCI Director, aka Nobel Prize Winner, aka Big Sexy, recently said in Cancer Letters that :

"we have to remember that the great achievements of science have almost always begun with an individual scientist—a lone explorer—working in his or her lab, having an unexpected idea. This in an essential precept to remain faithful to if we are going to retain the stature of the NCI, the NIH, and American science."

I swear I nearly jumped off my stool at the lab bench and cheered for this statement when I read it. Big Sexy gets it, he really does. Ground breaking work comes from individuals hunkering down in the lab who run some crazy experiment that they pulled out of their ass to get something to work and they make a major discovery, not from some damn -omics project. I know there is a lot of money spent on independent investigator sponsored research (aka the RO1 model) but they also spend a shit ton of money on these big projects. For example lets look at . . . More
Views: 221 | Comments: 9
Last by Lab Mom on Jul 31, 2010, 12:55am
I started up a blog on Blogspot a little over a year ago. The genesis of it was to get ideas off of my chest and vent my frustrations and get to know some people in the scientific blogging community. I have to say it has been nothing but a spectacular experience. If you haven't started a blog yet, get in the game man. So my scientific journey started out about 9 years ago when I got my first job as a bottle washer in a lab and worked my way up. Now I'm currently about to begin my 3rd year of a Ph.D. program (note I already have my M.S.). I've done everything from then until now including teach undergrads, work clinical trials, and other assorted crap. I feel that my drunken ambling through the field of science has given me a diverse background that helps me to this day. And its made me a lot of friends. So lets wrap this intro up and get into some blogging. Oh yeah, what's the profanity rule around here, I tend to swear a lot. . . . More
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