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Comments: 14 Last by Tim Skellett (Gurdur) on May 01, 2011, 4:14pm
This week's guest blogger is
Tim Skellett. He is an Australian, but these days lives semi-permanently in northwestern Germany. His interests range from nature to ecology, gardening, reading, metal- and hot-glass-work, and travelling. He is a frequent contributor to the
Guardian. He can be found on his Twitter account, at
@Gurdur or on
his blog.
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I once heard a woman talk, and I've never forgotten her, although I only heard about ten minutes of her speech, decades ago. I had a job in healthcare at the time, and part of my job was accompanying patients to Alcoholics Anonymous meetings; the woman was one of a quite a few speakers at that meeting. She had been diagosed with
Huntington's disease, which was a death sentence, and today still is; it was well-advanced, and meant she would die not all that long afterwards, and quite possibly in dementia. Huntingon's disease, also called Huntington's Chorea, is an autosomal dominant genetic, neurodegenerative disorder. So this woman had been handed one of life's truly nastily bad cards; one of her parents had had at least one particularly bad form of a specific gene,
Huntingtin. That malformation of one gene has a great many different possible outworkings because the gene is widely spread throughout the body, although concentrated in the brain. The different outworkings can lead to different symptoms being presented clinically, which creates problems for nosology - the science or philosophy of how we define diseases. Sufferers of Huntington's often enough commit suicide, and it can be very difficult to determine if such a sufferer is suicidal owing to one possible rational response to the thought of dying in such a manner as Huntington's, or because the Huntington's itself has caused suicidal ideation through pathological brain changes, which is known to happen in some sufferers. Huntington's, like other neurodegenerative diseases, affects intentionality, our power of choice of action, through affecting the brain.
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