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Researchers weigh methods to more accurately measure genome sequencing

Lost in the euphoria of the 2003 announcement that the human genome had been sequenced was a fundamental question: how can we be sure that an individual's genome has been read correctly?

Genetics | Source: New York University | Views: 70 | Comments: 0
Hearing metaphors activates brain regions involved in sensory experience

When a friend tells you she had a rough day, do you feel sandpaper under your fingers? The brain may be replaying sensory experiences to help understand common metaphors, new research suggests.

Neuroscience | Source: Emory University | Views: 84 | Comments: 0
Whole exome sequencing identifies cause of metabolic disease

Sequencing a patient's entire genome to discover the source of his or her disease is not routine – yet. But geneticists are getting close.

Genetics | Source: Emory University | Views: 165 | Comments: 0
Discovery of extremely long-lived proteins may provide insight into cell aging

One of the big mysteries in biology is why cells age. Now scientists at the Salk Institute for Biological Studies report that they have discovered a weakness in a component of brain cells that may explain how the aging process occurs in the brain.

Molecular Biology | Source: Salk Institute | Views: 172 | Comments: 0
Parasites or not? Transposable elements in fruit flies

Nearly all organisms contain pieces of DNA that do not really belong to them. These "transposable elements", so called because they are capable of moving around within and between genomes, generally represent a drain on the host's resources and in certain cases may lead directly to disease, e.g. when they insert themselves within an essential host gene. The factors that govern the spread of tran

Genetics | Source: University of Veterinary Medicine -- Vienna | Views: 127 | Comments: 1
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More Bioscience News
Parasites or not? Transposable elements in fruit flies

Nearly all organisms contain pieces of DNA that do not really belong to them. These "transposable elements", so called because they are capable of moving around within and between genomes, generally represent a drain on the host's resources and in certain cases may lead directly to disease, e.g. when they insert themselves within an essential host gene. The factors that govern the spread of tran

Genetics | Source: University of Veterinary Medicine -- Vienna | Views: 127 | Comments: 1
New procedure repairs severed nerves in minutes, restoring limb use in days or weeks

American scientists believe a new procedure to repair severed nerves could result in patients recovering in days or weeks, rather than months or years. The team used a cellular mechanism similar to that used by many invertebrates to repair damage to nerve axons. Their results are published today in the Journal of Neuroscience Research.

Neuroscience | Source: Wiley-Blackwell | Views: 135 | Comments: 0
Football findings suggest concussions caused by series of hits

A two-year study of high school football players suggests that concussions are likely caused by many hits over time and not from a single blow to the head, as commonly believed.

Neuroscience | Source: Purdue University | Views: 120 | Comments: 0
Scientists coax shy microorganisms to stand out in a crowd

The communities of marine microorganisms that make up half the biomass in the oceans and are responsible for half the photosynthesis the world over, mostly remain enigmatic. A few abundant groups have had their genomes described, but the natures and functions of the rest remain mysterious.

Microbiology | Source: University of Washington | Views: 133 | Comments: 0
Gene regulator in brain's executive hub tracked across lifespan -- NIH study

For the first time, scientists have tracked the activity, across the lifespan, of an environmentally responsive regulatory mechanism that turns genes on and off in the brain's executive hub. Among key findings of the study by National Institutes of Health scientists: genes implicated in schizophrenia and autism turn out to be members of a select club of genes in which regulatory activity peaks dur

Genetics | Source: NIH/National Institute of Mental Health | Views: 131 | Comments: 1
'Goldilocks' gene could determine best treatment for TB patients

'Goldilocks' gene could determine best treatment for TB patients Tuberculosis patients may receive treatments in the future according to what version they have of a single 'Goldilocks' gene, says an international research team from Oxford University, King's College London, Vietnam and the USA.

Genetics | Source: King's College London | Views: 79 | Comments: 0
Study uncovers probable mechanism underlying resveratrol activity

National Institutes of Health researchers and their colleagues have identified how resveratrol, a naturally occurring chemical found in red wine and other plant products, may confer its health benefits. The authors present evidence that resveratrol does not directly activate sirtuin 1, a protein associated with aging. Rather, the authors found that resveratrol inhibits certain types of proteins kn

Molecular Biology | Source: NIH/National Heart, Lung and Blood Institute | Views: 69 | Comments: 0
Sex-specific behaviors traced to hormone-controlled genes in the brain

Men and women may be equals, but they often behave differently when it comes to sex and parenting. Now a study of the differences between the brains of male and female mice in the February 3rd issue of the Cell Press journal Cell provides insight into how our own brains might be programmed for these stereotypically different behaviors.

Neuroscience | Source: Cell Press | Views: 67 | Comments: 0
Identical twins reveal mechanisms behind aging

In a recent study led by Uppsala University, the researchers compared the DNA of identical (monozygotic) twins of different age. They could show that structural modifications of the DNA, where large or small DNA segments change direction, are duplicated or completely lost are more common in older people. The results may in part explain why the immune system is impaired with age.

Genetics | Source: Uppsala University | Views: 76 | Comments: 0
Video: Rearranging the cell's skeleton

Cell biologists at Johns Hopkins have identified key steps in how certain molecules alter a cell's skeletal shape and drive the cell's movement.

Molecular Biology | Source: Johns Hopkins Medical Institutions | Views: 72 | Comments: 0
Human immune cells react sensitively to 'stress'

Scientists working with Professor Bernd Kaina of the Institute of Toxicology at the Medical Center of Johannes Gutenberg University Mainz have demonstrated for the first time that certain cells circulating in human blood – so-called monocytes – are extremely sensitive to reactive oxygen species (ROS).

Molecular Biology | Source: Johannes Gutenberg Universitaet Mainz | Views: 78 | Comments: 0
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