Pathological aging (PA) is used to describe the brains of people which have Alzheimer's disease (AD)-like pathology but where the person showed no signs of cognitive impairment whilst they were alive. New research, published in BioMed Central's open access journal Alzheimer's Research & Therapy, shows that PA and AD brains contain similar amyloid β (Aβ) plaques and that while on a

Street lighting is transforming communities of insects and other invertebrates, according to research by the University of Exeter. Published today (23 May 2012) in the journal Biology Letters, the study shows for the first time that the balance of different species living together is being radically altered as a result of light pollution in our towns and cities.

Environmental change is the selective force that preserves adaptive traits in organisms and is a primary driver of evolution. However, it is less well known that evolutionary change in organisms also trigger fundamental changes in the environment.

To modify a metal surface at the scale of atoms and molecules — for instance to refine the wiring in computer chips or the reflective silver in optical components — manufacturers shower it with ions. While the process may seem high-tech and precise, the technique has been limited by the lack of understanding of the underlying physics. In a new study, Brown Uni

For the first time scientists have succeeded in taking skin cells from heart failure patients and reprogramming them to transform into healthy, new heart muscle cells that are capable of integrating with existing heart tissue.

For decades, scientists believed that a spine with multiple segments was an exclusive feature of land-dwelling animals. But the discovery of the same anatomical feature in a 345-million-year-old eel suggests that this complex anatomy arose separately from – and perhaps before – the first species to walk on land.

The stubby arms of Tyrannosaurus rex obviously weren't designed for hand-to-hand combat. However, the abelisaurids of the Southern hemisphere were even less well equipped in that department–and upper limb reduction began very early in their evolution.

New fish-tagging studies of young bluefin tuna in Atlantic waters off New England by researchers at the University of Massachusetts Amherst are offering the first fishery-independent, year-round data on dispersal patterns and habitat use for the popular game fish. The availability of miniaturized pop-up satellite tags suitable for smaller (two- to five-year-old) fish helped make t

A special feature in this week's issue of the journal Science highlights protein array technology, touching on research conducted by Joshua LaBaer, director of the Biodesign Institute's Virginia G. Piper Center for Personalized Diagnostics.

The uproar that began last year when the U.S. Preventive Services Task Force stated that doctors should no longer offer regular prostate-cancer tests to healthy men continued this week when the task force released their final report. Overall, they stuck to their guns, stating that a blood test commonly used to screen for prostate cancer, the PSA test, causes more harm than good — it le