Neuroscience Source: University of Oxford
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Tuesday, Feb 12, 2013, 4:30pm Rating: | Views: 1213 | Comments: 0
Researchers find possible genetic clues to organ development, birth defects Using cutting-edge time-lapse photography, University of Southern California (USC) researchers have discovered clues to the development of the head at the cellular level, which could point scientists to a better understanding of how organs and birth defects form in humans.
Development Source: University of Southern California - Health Sciences
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Tuesday, Feb 12, 2013, 4:00pm Rating: | Views: 1159 | Comments: 0
Researchers identify genetic root to early-onset prostate cancer Prostate cancer is often considered an elderly man's disease, and little is known about the approximately 2% of cases that arise in men who are aged 50 years or younger. Research published in the February 11th issue of the Cell Press journal Cancer Cell uncovers the genetic origin of such early-onset prostate cancer. The findings could help in the development of new diagnostic, prognostic,
Genetics Source: Cell Press
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Tuesday, Feb 12, 2013, 12:45pm Rating: | Views: 1240 | Comments: 0
Mouse model improves understanding of clear cell sarcoma Geneticists led by University of Utah Nobel Prize Laureate Mario R. Capecchi, Ph.D., have engineered mice that develop clear cell sarcoma (CCS), a significant step in better understanding how this rare and deadly soft tissue cancer arises. The mouse model also can potentially speed the development of drugs to target genes that must be activated for the cancer to form.
Cancer Source: University of Utah Health Sciences
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Tuesday, Feb 12, 2013, 12:30pm Rating: | Views: 1173 | Comments: 0
New strategy prevents rheumatoid arthritis in mice Farber Cancer Institute scientists have demonstrated a new strategy for treating autoimmune disease that successfully blocked the development of rheumatoid arthritis in a mouse model. They say it holds promise for improved treatment of arthritis and other autoimmune disorders in people.
Immunology Source: Dana-Farber Cancer Institute
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Monday, Feb 11, 2013, 10:15am Rating: | Views: 1388 | Comments: 0
Development Source: Genetics Society of America
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Monday, Feb 11, 2013, 8:15am Rating: | Views: 1142 | Comments: 0
Protein paves the way for correct stem cell differentiation A single embryonic stem cell can develop into more than 200 specialized cell types that make up our body. This maturation process is called differentiation and is tightly regulated. If the regulation is lost, specialized cells cannot develop correctly during development. In adulthood, the specialized cells may forget their identity and develop into cancer cells. Research from BRIC, University of C
Molecular Biology Source: University of Copenhagen
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Friday, Feb 08, 2013, 4:00pm Rating: | Views: 1358 | Comments: 0
Colon cancer exhibits a corresponding epigenetic pattern in mice and humans Tumourigenesis is driven by genetic alterations and by changes in the epigenome, for instance by the addition of methyl groups to cytosine bases in the DNA. A deeper understanding of the interaction between the genetic and epigenetic mechanisms is critical for the selection of tumour biomarkers and for the future development of therapies.
Molecular Biology Source: Max-Planck-Gesellschaft
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Friday, Feb 08, 2013, 2:15pm Rating: | Views: 1317 | Comments: 0
Biologists map rare case of fitness-reducing interaction in nuclear, mitochondrial DNA A team of biologists from Indiana University and Brown University believes it has discovered the mechanism by which interacting mutations in mitochondrial and nuclear DNA produce an incompatible genotype that reduces reproductive fitness and delays development in fruit flies.
Development Source: Indiana University
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Wednesday, Feb 06, 2013, 12:15pm Rating: | Views: 1146 | Comments: 0
The zebrafish revealed a central regulator for the development of the brain histamine system Research has shown that mutations in the psen1 gene are common in the familial forms of Alzheimer's disease, and the Presenilin-1 protein that the gene encodes is known to be involved in the cleavage of the amyloid precursor protein. In Alzheimer's disease the amyloid precursor protein is not cleaved the normal way, and the protein accumulates in the brain damaging neuronal tracts and neurons. It
Neuroscience Source: University of Helsinki
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Wednesday, Feb 06, 2013, 10:00am Rating: | Views: 1134 | Comments: 0
If you are impulsive, take modafinil and count to 10 Poor impulse control contributes to one's inability to control the consumption of rewarding substances, like food, alcohol, and other drugs. This can lead to the development of addiction. FDA-approved medications for alcoholism, like naltrexone (Revia) and disulfiram (Antabuse), are thought to reduce alcohol consumption by curbing cravings and creating unpleasa
Neuroscience Source: Elsevier
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Monday, Feb 04, 2013, 10:15am Rating: | Views: 1117 | Comments: 0
Understanding 'master regulator' genes could lead to better cancer treatments Cell division is serious business. Cells that divide incorrectly can lead to birth defects or set the stage for cancer. A new discovery from the Oklahoma Medical Research Foundation has identified how two genes work together to make sure chromosomes are distributed properly when cells divide, providing new insights that could contribute to the future development of cancer treatments.
Genetics Source: Oklahoma Medical Research Foundation
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Friday, Feb 01, 2013, 2:30pm Rating: | Views: 1221 | Comments: 0
Epigenetic control of cardiogenesis Many different tissues and organs form from pluripotent stem cells during embryonic development. To date it had been known that these processes are controlled by transcription factors for specific tissues.
Genetics Source: Max-Planck-Gesellschaft
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Wednesday, Jan 30, 2013, 11:00am Rating: | Views: 1202 | Comments: 0
Protein family linked to autism suppresses the development of inhibitory synapses Synapse development is promoted by a variety of cell adhesion molecules that connect neurons and organize synaptic proteins. Many of these adhesion molecules are linked to neurodevelopmental disorders; mutations in neuroligin and neurexin proteins, for example, are associated with autism and schizophrenia. According to a study in The Journal of Cell Biology, another family of proteins linked to th
Neuroscience Source: Rockefeller University Press
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Tuesday, Jan 29, 2013, 12:45pm Rating: | Views: 1324 | Comments: 0
Black silicon can take efficiency of solar cells to new levels Scientists at Aalto University, Finland, have demonstrated results that show a huge improvement in the light absorption and the surface passivation on highly absorbing silicon nanostructures. This has been achieved by applying atomic layer coating. The results advance the development of devices that require high sensitivity light response such as high efficiency solar cells.
Energy Source: Aalto University
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Monday, Jan 28, 2013, 8:45am Rating: | Views: 1179 | Comments: 0
Neuroscience Source: University of Wisconsin-Madison
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Friday, Jan 25, 2013, 4:45pm Rating: | Views: 1184 | Comments: 0
Discovery of new class of damage-prone DNA regions could lead to better cancer treatments Cancer is thought to arise from DNA damage at fragile sites in the genome. A study published by Cell Press on January 24th in the journal Cell reveals a new class of fragile sites that contributes to DNA alterations in a type of blood cancer called B cell lymphoma The findings could lead to the development of more effective treatments for B cell lymphoma and potentially other cancers.
Genetics Source: Cell Press
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Friday, Jan 25, 2013, 11:45am Rating: | Views: 1246 | Comments: 0
Children's complex thinking skills begin forming before they go to school New research at the University of Chicago and the University of North Carolina at Chapel Hill shows that children begin to show signs of higher-level thinking skills as young as age 4 ½. Researchers have previously attributed higher-order thinking development to knowledge acquisition and better schooling, but the new longitudinal study shows that other skills, not always connected with knowledge,
Psychology Source: University of Chicago
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Thursday, Jan 24, 2013, 4:00pm Rating: | Views: 1532 | Comments: 0
Oxygen-free energy designed to fuel brain development spurs on growth of cancer The metabolic process which fuels the growth of many cancers has its origins in normal brain growth finds a new study published in BioMed Central's open access journal Cancer & Metabolism. Using knock-out mice the study shows that interfering with Hexokinase-2 (Hk2), an enzyme integral to glucose metabolism, reduces the aggressiveness of medulloblastoma, the most common malignant brain tumo
Cancer Source: BioMed Central
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Thursday, Jan 24, 2013, 11:15am Rating: | Views: 1216 | Comments: 0
BPA substitute could spell trouble A few years ago, manufacturers of water bottles, food containers, and baby products had a big problem. A key ingredient of the plastics they used to make their merchandise, an organic compound called bisphenol A, had been linked by scientists to diabetes, asthma and cancer and altered prostate and neurological development. The FDA and state legislatures were considering action to restrict BPA's us
Health Source: University of Texas Medical Branch at Galveston
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Thursday, Jan 24, 2013, 11:00am Rating: | Views: 1306 | Comments: 0
Molecular Biology Source: University at Buffalo
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Thursday, Jan 24, 2013, 10:30am Rating: | Views: 1184 | Comments: 0
A diffusion trap Over the past several years, Rong Li, Ph.D., at the Stowers Institute for Medical Research has been making crucial discoveries about the development of cell polarity—the process by which one side of a cell becomes different from the other side. Such polarity is critical for the functioning of the vast majority of cells. The outside surface of skin cells is very different from the
Molecular Biology Source: Stowers Institute for Medical Research
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Wednesday, Jan 23, 2013, 1:30pm Rating: | Views: 1172 | Comments: 0
Genetics Source: Johns Hopkins Medicine
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Wednesday, Jan 23, 2013, 8:15am Rating: | Views: 1176 | Comments: 0
Developing microbial cell factories by employing synthetic small regulatory RNAs Biotechnologists have been working hard to address the climate change and limited fossil resource issues through the development of sustainable processes for the production of chemicals, fuels and materials from renewable non-food biomass. One promising sustainable technology is the use of microbial cell factories for the efficient production of desired chemicals and materials. When microorganisms
Molecular Biology Source: The Korea Advanced Institute of Science and Technology (KAIST)
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Tuesday, Jan 22, 2013, 12:30pm Rating: | Views: 1171 | Comments: 0
Novel technique reveals dynamics of telomere DNA structure Biomedical researchers studying aging and cancer are intensely interested in telomeres, the protective caps on the ends of chromosomes. In a new study, scientists at UC Santa Cruz used a novel technique to reveal structural and mechanical properties of telomeres that could help guide the development of new anti-cancer drugs.
Genetics Source: University of California - Santa Cruz
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Friday, Jan 18, 2013, 2:15pm Rating: | Views: 1260 | Comments: 0
Drug targets hard-to-reach leukemia stem cells responsible for relapses Researchers at the University of California, San Diego School of Medicine have discovered that hard-to-reach, drug-resistant leukemia stem cells (LSCs) that overexpress multiple pro-survival protein forms are sensitive – and thus vulnerable – to a novel cancer stem cell-targeting drug currently under development.
Cancer Source: University of California - San Diego
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Friday, Jan 18, 2013, 12:00pm Rating: | Views: 1576 | Comments: 0
New research finds slower growth of preterm infants linked to altered brain development Preterm infants who grow more slowly as they approached what would have been their due dates also have slower development in an area of the brain called the cerebral cortex, report Canadian researchers in a new study published today in Science Translational Medicine.
Neuroscience Source: Child & Family Research Institute
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Thursday, Jan 17, 2013, 2:15pm Rating: | Views: 1187 | Comments: 0
Development Source: Cincinnati Children's Hospital Medical Center
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Thursday, Jan 17, 2013, 12:30pm Rating: | Views: 1201 | Comments: 0
New surfaces repel most known liquids In an advance toward stain-proof, spill-proof clothing, protective garments and other products that shrug off virtually every liquid — from blood and ketchup to concentrated acids — scientists are reporting development of new "superomniphobic" surfaces. Their report on surfaces that display extreme repellency to two families of liquids — Newtonian and non-Newtonian liquids — appears in the Jour
Materials Science Source: American Chemical Society
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Thursday, Jan 17, 2013, 11:45am Rating: | Views: 1418 | Comments: 0
Genetics plays major role in victimization in elementary school Genetics plays a major role in peer rejection and victimization in early elementary school, according to a study recently published on the website of the journal Child Development by a team directed by Dr. Michel Boivin, a research professor at Université Laval's School of Psychology.
Genetics Source: University Laval
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Thursday, Jan 17, 2013, 10:00am Rating: | Views: 1267 | Comments: 0