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Spring cleaning in your brain: New stem cell research shows how important it is 
Deep inside your brain, a legion of stem cells lies ready to turn into new brain and nerve cells whenever and wherever you need them most. While they wait, they keep themselves in a state of perpetual readiness – poised to become any type of nerve cell you might need as your cells age or get damaged.
Deep inside your brain, a legion of stem cells lies ready to turn into new brain and nerve cells whenever and wherever you need them most. While they wait, they keep themselves in a state of perpetual readiness – poised to become any type of nerve cell you might need as your cells age or get damaged.
Neuroscience
Source: University of Michigan Health System
Posted on: Thursday, Apr 11, 2013, 2:45pm
Rating: | Views: 1756 | Comments: 0
Source: University of Michigan Health System
Posted on: Thursday, Apr 11, 2013, 2:45pm
Rating: | Views: 1756 | Comments: 0
Cardiopoietic 'smart' stem cells show promise in heart failure patients
Translating a Mayo Clinic stem-cell discovery, an international team has demonstrated that therapy with cardiopoietic (cardiogenically-instructed) or "smart" stem cells can improve heart health for people suffering from heart failure. This is the first application in patients of lineage-guided stem cells for targeted regeneration of a failing organ, paving the way to developmen
Translating a Mayo Clinic stem-cell discovery, an international team has demonstrated that therapy with cardiopoietic (cardiogenically-instructed) or "smart" stem cells can improve heart health for people suffering from heart failure. This is the first application in patients of lineage-guided stem cells for targeted regeneration of a failing organ, paving the way to developmen
Stem cells
Source: Mayo Clinic
Posted on: Thursday, Apr 11, 2013, 2:30pm
Rating: | Views: 1385 | Comments: 0
Source: Mayo Clinic
Posted on: Thursday, Apr 11, 2013, 2:30pm
Rating: | Views: 1385 | Comments: 0
Researchers show stem cell fate depends on 'grip'
The field of regenerative medicine holds great promise, propelled by greater understanding of how stem cells differentiate themselves into many of the body's different cell types. But clinical applications in the field have been slow to materialize, partially owing to difficulties in replicating the conditions these cells naturally experience.
The field of regenerative medicine holds great promise, propelled by greater understanding of how stem cells differentiate themselves into many of the body's different cell types. But clinical applications in the field have been slow to materialize, partially owing to difficulties in replicating the conditions these cells naturally experience.
Molecular Biology
Source: University of Pennsylvania
Posted on: Friday, Mar 29, 2013, 1:15pm
Rating: | Views: 1591 | Comments: 0
Source: University of Pennsylvania
Posted on: Friday, Mar 29, 2013, 1:15pm
Rating: | Views: 1591 | Comments: 0
Stem cells use signal orientation to guide division
Cells in the body need to be acutely aware of their surroundings. A signal from one direction may cause a cell to react in a very different way than if it had come from another direction. Unfortunately for researchers, such vital directional cues are lost when cells are removed from their natural environment to grow in an artificial broth of nutrients and growth factors.
Cells in the body need to be acutely aware of their surroundings. A signal from one direction may cause a cell to react in a very different way than if it had come from another direction. Unfortunately for researchers, such vital directional cues are lost when cells are removed from their natural environment to grow in an artificial broth of nutrients and growth factors.
Stem cells
Source: Stanford University Medical Center
Posted on: Friday, Mar 22, 2013, 8:45am
Rating: | Views: 1390 | Comments: 0
Source: Stanford University Medical Center
Posted on: Friday, Mar 22, 2013, 8:45am
Rating: | Views: 1390 | Comments: 0
Sweet news for stem cell
Scientists have used sugar-coated scaffolding to move a step closer to the routine use of stem cells in the clinic and unlock their huge potential to cure diseases from Alzheimer's to diabetes.
Scientists have used sugar-coated scaffolding to move a step closer to the routine use of stem cells in the clinic and unlock their huge potential to cure diseases from Alzheimer's to diabetes.
Stem cells
Source: University of Manchester
Posted on: Wednesday, Feb 27, 2013, 8:15am
Rating: | Views: 1244 | Comments: 0
Source: University of Manchester
Posted on: Wednesday, Feb 27, 2013, 8:15am
Rating: | Views: 1244 | Comments: 0
Distinct niches in bone marrow nurture blood stem cells
In research that could one day improve the success of stem cell transplants and chemotherapy, scientists have found that distinct niches exist in bone marrow to nurture different types of blood stem cells.
In research that could one day improve the success of stem cell transplants and chemotherapy, scientists have found that distinct niches exist in bone marrow to nurture different types of blood stem cells.
Development
Source: Washington University School of Medicine
Posted on: Monday, Feb 25, 2013, 2:30pm
Rating: | Views: 1289 | Comments: 0
Source: Washington University School of Medicine
Posted on: Monday, Feb 25, 2013, 2:30pm
Rating: | Views: 1289 | Comments: 0
Protein central to cancer stem cell formation provides new potential target
Researchers have identified a pivotal protein in a cellular transformation that makes a cancer cell more resistant to treatment and more capable of growing and spreading, making it an inviting new target for drug development.
Researchers have identified a pivotal protein in a cellular transformation that makes a cancer cell more resistant to treatment and more capable of growing and spreading, making it an inviting new target for drug development.
Cancer
Source: University of Texas M. D. Anderson Cancer Center
Posted on: Thursday, Feb 14, 2013, 12:45pm
Rating: | Views: 1193 | Comments: 0
Source: University of Texas M. D. Anderson Cancer Center
Posted on: Thursday, Feb 14, 2013, 12:45pm
Rating: | Views: 1193 | Comments: 0
Stem cell discovery gives insight into motor neurone disease
A discovery using stem cells from a patient with motor neurone disease could help research into treatments for the condition. The study used a patient's skin cells to create motor neurons - nerve cells that control muscle activity - and the cells that support them called astrocytes.
A discovery using stem cells from a patient with motor neurone disease could help research into treatments for the condition. The study used a patient's skin cells to create motor neurons - nerve cells that control muscle activity - and the cells that support them called astrocytes.
Neuroscience
Source: University of Edinburgh
Posted on: Tuesday, Feb 12, 2013, 5:30pm
Rating: | Views: 1323 | Comments: 0
Source: University of Edinburgh
Posted on: Tuesday, Feb 12, 2013, 5:30pm
Rating: | Views: 1323 | Comments: 0
Protein paves the way for correct stem cell differentiation
A single embryonic stem cell can develop into more than 200 specialized cell types that make up our body. This maturation process is called differentiation and is tightly regulated. If the regulation is lost, specialized cells cannot develop correctly during development. In adulthood, the specialized cells may forget their identity and develop into cancer cells. Research from BRIC, University of C
A single embryonic stem cell can develop into more than 200 specialized cell types that make up our body. This maturation process is called differentiation and is tightly regulated. If the regulation is lost, specialized cells cannot develop correctly during development. In adulthood, the specialized cells may forget their identity and develop into cancer cells. Research from BRIC, University of C
Molecular Biology
Source: University of Copenhagen
Posted on: Friday, Feb 08, 2013, 4:00pm
Rating: | Views: 1358 | Comments: 0
Source: University of Copenhagen
Posted on: Friday, Feb 08, 2013, 4:00pm
Rating: | Views: 1358 | Comments: 0
Learning from the linker
Mature cells can be reprogrammed to pluripotency and thus regain the ability to divide and differentiate into specialized cell types. Although these so-called induced pluripotent stem cells (iPS cells) represent a milestone in stem cell research, many of the biochemical processes that underlie reprogramming are still not understood. Scientists from the EMBL Hamburg and from the Max Planck Institut
Mature cells can be reprogrammed to pluripotency and thus regain the ability to divide and differentiate into specialized cell types. Although these so-called induced pluripotent stem cells (iPS cells) represent a milestone in stem cell research, many of the biochemical processes that underlie reprogramming are still not understood. Scientists from the EMBL Hamburg and from the Max Planck Institut
Molecular Biology
Source: European Molecular Biology Laboratory
Posted on: Thursday, Feb 07, 2013, 10:45am
Rating: | Views: 1259 | Comments: 0
Source: European Molecular Biology Laboratory
Posted on: Thursday, Feb 07, 2013, 10:45am
Rating: | Views: 1259 | Comments: 0
Fighting fat with fat: Stem cell discovery identifies potential obesity treatment
Ottawa scientists have discovered a trigger that turns muscle stem cells into brown fat, a form of good fat that could play a critical role in the fight against obesity. The findings from Dr. Michael Rudnicki's lab, based at the Ottawa Hospital Research Institute, were published today in the prestigious journal Cell Metabolism.
Ottawa scientists have discovered a trigger that turns muscle stem cells into brown fat, a form of good fat that could play a critical role in the fight against obesity. The findings from Dr. Michael Rudnicki's lab, based at the Ottawa Hospital Research Institute, were published today in the prestigious journal Cell Metabolism.
Health
Source: Ottawa Hospital Research Institute
Posted on: Wednesday, Feb 06, 2013, 1:30pm
Rating: | Views: 1478 | Comments: 0
Source: Ottawa Hospital Research Institute
Posted on: Wednesday, Feb 06, 2013, 1:30pm
Rating: | Views: 1478 | Comments: 0
Growth factor aids stem cell regeneration after radiation damage
Epidermal growth factor has been found to speed the recovery of blood-making stem cells after exposure to radiation, according to Duke Medicine researchers. The finding could open new options for treating cancer patients and victims of dirty bombs or nuclear disasters.
Epidermal growth factor has been found to speed the recovery of blood-making stem cells after exposure to radiation, according to Duke Medicine researchers. The finding could open new options for treating cancer patients and victims of dirty bombs or nuclear disasters.
Molecular Biology
Source: Duke University Medical Center
Posted on: Monday, Feb 04, 2013, 11:45am
Rating: | Views: 1365 | Comments: 0
Source: Duke University Medical Center
Posted on: Monday, Feb 04, 2013, 11:45am
Rating: | Views: 1365 | Comments: 0
Patients' own skin cells are transformed into heart cells to create 'disease in a dish'
Most patients with an inherited heart condition known as arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) don't know they have a problem until they're in their early 20s. The lack of symptoms at younger ages makes it very difficult for researchers to study how ARVD/C evolves or to develop treatments. A new stem cell-based technology created by
Most patients with an inherited heart condition known as arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) don't know they have a problem until they're in their early 20s. The lack of symptoms at younger ages makes it very difficult for researchers to study how ARVD/C evolves or to develop treatments. A new stem cell-based technology created by
Molecular Biology
Source: Sanford-Burnham Medical Research Institute
Posted on: Monday, Jan 28, 2013, 11:45am
Rating: | Views: 1339 | Comments: 0
Source: Sanford-Burnham Medical Research Institute
Posted on: Monday, Jan 28, 2013, 11:45am
Rating: | Views: 1339 | Comments: 0
Study shows potential of differentiated iPS cells in cell therapy without immune rejection
A new study from Boston University School of Medicine (BUSM) shows that tissues derived from induced pluripotent stem (iPS) cells in an experimental model were not rejected when transplanted back into genetically identical recipients. The study, published online in Cell Stem Cell, demonstrates the potential of utilizing iPS cells to develop cell types that could offer treatment f
A new study from Boston University School of Medicine (BUSM) shows that tissues derived from induced pluripotent stem (iPS) cells in an experimental model were not rejected when transplanted back into genetically identical recipients. The study, published online in Cell Stem Cell, demonstrates the potential of utilizing iPS cells to develop cell types that could offer treatment f
Stem cells
Source: Boston University Medical Center
Posted on: Monday, Jan 28, 2013, 11:15am
Rating: | Views: 1298 | Comments: 0
Source: Boston University Medical Center
Posted on: Monday, Jan 28, 2013, 11:15am
Rating: | Views: 1298 | Comments: 0
Stem cell research helps to identify origins of schizophrenia
New University at Buffalo research demonstrates how defects in an important neurological pathway in early development may be responsible for the onset of schizophrenia later in life.
New University at Buffalo research demonstrates how defects in an important neurological pathway in early development may be responsible for the onset of schizophrenia later in life.
Molecular Biology
Source: University at Buffalo
Posted on: Thursday, Jan 24, 2013, 10:30am
Rating: | Views: 1184 | Comments: 0
Source: University at Buffalo
Posted on: Thursday, Jan 24, 2013, 10:30am
Rating: | Views: 1184 | Comments: 0
Researchers turn one form of neuron into another in the brain
A new finding by Harvard stem cell biologists turns one of the basics of neurobiology on its head – demonstrating that it is possible to turn one type of already differentiated neuron into another within the brain.
A new finding by Harvard stem cell biologists turns one of the basics of neurobiology on its head – demonstrating that it is possible to turn one type of already differentiated neuron into another within the brain.
Neuroscience
Source: Harvard University
Posted on: Tuesday, Jan 22, 2013, 11:45am
Rating: | Views: 1128 | Comments: 0
Source: Harvard University
Posted on: Tuesday, Jan 22, 2013, 11:45am
Rating: | Views: 1128 | Comments: 0
Bacteria's hidden skill could pave way for stem cell treatments
A discovery about the way in which bugs spread throughout the body could help to develop stem cell treatments.
A discovery about the way in which bugs spread throughout the body could help to develop stem cell treatments.
Microbiology
Source: University of Edinburgh
Posted on: Friday, Jan 18, 2013, 1:00pm
Rating: | Views: 1341 | Comments: 0
Source: University of Edinburgh
Posted on: Friday, Jan 18, 2013, 1:00pm
Rating: | Views: 1341 | Comments: 0
Drug targets hard-to-reach leukemia stem cells responsible for relapses
Researchers at the University of California, San Diego School of Medicine have discovered that hard-to-reach, drug-resistant leukemia stem cells (LSCs) that overexpress multiple pro-survival protein forms are sensitive – and thus vulnerable – to a novel cancer stem cell-targeting drug currently under development.
Researchers at the University of California, San Diego School of Medicine have discovered that hard-to-reach, drug-resistant leukemia stem cells (LSCs) that overexpress multiple pro-survival protein forms are sensitive – and thus vulnerable – to a novel cancer stem cell-targeting drug currently under development.
Cancer
Source: University of California - San Diego
Posted on: Friday, Jan 18, 2013, 12:00pm
Rating: | Views: 1574 | Comments: 0
Source: University of California - San Diego
Posted on: Friday, Jan 18, 2013, 12:00pm
Rating: | Views: 1574 | Comments: 0
New insights into how leprosy infection spreads could pave the way for early intervention
Leprosy is a bacterial disease that spreads to muscles and other tissues in the body, causing neurodegeneration and muscle weakness. A new study, published by Cell Press January 17th in the journal Cell, reveals that the bacteria responsible for leprosy spread infection by hijacking specialized cells in the adult nervous system, reprogramming them into a stem cell-like state, and converting
Leprosy is a bacterial disease that spreads to muscles and other tissues in the body, causing neurodegeneration and muscle weakness. A new study, published by Cell Press January 17th in the journal Cell, reveals that the bacteria responsible for leprosy spread infection by hijacking specialized cells in the adult nervous system, reprogramming them into a stem cell-like state, and converting
Molecular Biology
Source: Cell Press
Posted on: Friday, Jan 18, 2013, 11:15am
Rating: | Views: 1700 | Comments: 0
Source: Cell Press
Posted on: Friday, Jan 18, 2013, 11:15am
Rating: | Views: 1700 | Comments: 0
Stem-cell approach shows promise for Duchenne muscular dystrophy
Researchers have shown that transplanting stem cells derived from normal mouse blood vessels into the hearts of mice that model the pathology associated with Duchenne muscular dystrophy (DMD) prevents the decrease in heart function associated with DMD.
Researchers have shown that transplanting stem cells derived from normal mouse blood vessels into the hearts of mice that model the pathology associated with Duchenne muscular dystrophy (DMD) prevents the decrease in heart function associated with DMD.
Molecular Biology
Source: University of Illinois at Urbana-Champaign
Posted on: Tuesday, Jan 15, 2013, 11:30am
Rating: | Views: 1283 | Comments: 0
Source: University of Illinois at Urbana-Champaign
Posted on: Tuesday, Jan 15, 2013, 11:30am
Rating: | Views: 1283 | Comments: 0
Ovarian cancer stem cell study puts targeted therapies within reach
Researchers at Yale School of Medicine have identified a key link between stem cell factors that fuel ovarian cancer's growth and patient prognosis. The study, which paves the way for developing novel targeted ovarian cancer therapies, is published online in the current issue of Cell Cycle.
Researchers at Yale School of Medicine have identified a key link between stem cell factors that fuel ovarian cancer's growth and patient prognosis. The study, which paves the way for developing novel targeted ovarian cancer therapies, is published online in the current issue of Cell Cycle.
Cancer
Source: Yale University
Posted on: Tuesday, Jan 08, 2013, 8:30am
Rating: | Views: 1154 | Comments: 0
Source: Yale University
Posted on: Tuesday, Jan 08, 2013, 8:30am
Rating: | Views: 1154 | Comments: 0
Research uncovers new insight into cell development and cancer
Long-standing research efforts have been focused on understanding how stem cells, cells capable of transforming into any type of cell in the body, are capable of being programmed down a defined path to contribute to the development of a specific organ like a heart, lung, or kidney. Research from the University of North Carolina at Chapel Hill School of Medicine has shed new light on
Long-standing research efforts have been focused on understanding how stem cells, cells capable of transforming into any type of cell in the body, are capable of being programmed down a defined path to contribute to the development of a specific organ like a heart, lung, or kidney. Research from the University of North Carolina at Chapel Hill School of Medicine has shed new light on
Molecular Biology
Source: University of North Carolina Health Care
Posted on: Wednesday, Jan 02, 2013, 5:00pm
Rating: | Views: 1211 | Comments: 0
Source: University of North Carolina Health Care
Posted on: Wednesday, Jan 02, 2013, 5:00pm
Rating: | Views: 1211 | Comments: 0
Enzyme accelerates malignant stem cell cloning in chronic myeloid leukemia
An international team, headed by researchers at the University of California, San Diego School of Medicine, has identified a key enzyme in the reprogramming process that promotes malignant stem cell cloning and the growth of chronic myeloid leukemia (CML), a cancer of the blood and marrow that experts say is increasing in prevalence.
An international team, headed by researchers at the University of California, San Diego School of Medicine, has identified a key enzyme in the reprogramming process that promotes malignant stem cell cloning and the growth of chronic myeloid leukemia (CML), a cancer of the blood and marrow that experts say is increasing in prevalence.
Cancer
Source: University of California - San Diego
Posted on: Wednesday, Jan 02, 2013, 1:30pm
Rating: | Views: 1540 | Comments: 0
Source: University of California - San Diego
Posted on: Wednesday, Jan 02, 2013, 1:30pm
Rating: | Views: 1540 | Comments: 0
Protein kinase Akt identified as arbiter of cancer stem cell fate
The protein kinase Akt is a key regulator of cell growth, proliferation, metabolism, survival, and death. New work on Akt's role in cancer stem cell biology from the lab of senior author Honglin Zhou, MD, PhD and Weihua Li, co-first author, both from the Center for Resuscitation Sciences, Department of Emergency Medicine, Perelman School of Medicine, University of Pennsylvania, and
The protein kinase Akt is a key regulator of cell growth, proliferation, metabolism, survival, and death. New work on Akt's role in cancer stem cell biology from the lab of senior author Honglin Zhou, MD, PhD and Weihua Li, co-first author, both from the Center for Resuscitation Sciences, Department of Emergency Medicine, Perelman School of Medicine, University of Pennsylvania, and
Molecular Biology
Source: University of Pennsylvania School of Medicine
Posted on: Friday, Dec 21, 2012, 2:00pm
Rating: | Views: 1622 | Comments: 0
Source: University of Pennsylvania School of Medicine
Posted on: Friday, Dec 21, 2012, 2:00pm
Rating: | Views: 1622 | Comments: 0
Scientists develop technique to help prevent inherited disorders in humans
A joint team of scientists from The New York Stem Cell Foundation (NYSCF) Laboratory and Columbia University Medical Center (CUMC) has developed a technique that may prevent the inheritance of mitochondrial diseases in children. The study is published online today in Nature.
A joint team of scientists from The New York Stem Cell Foundation (NYSCF) Laboratory and Columbia University Medical Center (CUMC) has developed a technique that may prevent the inheritance of mitochondrial diseases in children. The study is published online today in Nature.
Molecular Biology
Source: Columbia University Medical Center
Posted on: Thursday, Dec 20, 2012, 2:00pm
Rating: | Views: 1211 | Comments: 0
Source: Columbia University Medical Center
Posted on: Thursday, Dec 20, 2012, 2:00pm
Rating: | Views: 1211 | Comments: 0
Stem cell research provides hope for infertile cancer survivors
Radiation and chemotherapy can pack a powerful punch against all kinds of cancers. Those who survive, however, are often left with bad news: Their treatments have rendered them infertile.
Radiation and chemotherapy can pack a powerful punch against all kinds of cancers. Those who survive, however, are often left with bad news: Their treatments have rendered them infertile.
Stem cells
Source: University of Texas at San Antonio
Posted on: Tuesday, Dec 11, 2012, 10:45am
Rating: | Views: 1141 | Comments: 0
Source: University of Texas at San Antonio
Posted on: Tuesday, Dec 11, 2012, 10:45am
Rating: | Views: 1141 | Comments: 0
Scientists develop faster, safer method for producing stem cells
A new method for generating stem cells from mature cells promises to boost stem cell production in the laboratory, helping to remove a barrier to regenerative medicine therapies that would replace damaged or unhealthy body tissues.
A new method for generating stem cells from mature cells promises to boost stem cell production in the laboratory, helping to remove a barrier to regenerative medicine therapies that would replace damaged or unhealthy body tissues.
Molecular Biology
Source: Salk Institute
Posted on: Wednesday, Dec 05, 2012, 8:45am
Rating: | Views: 1215 | Comments: 0
Source: Salk Institute
Posted on: Wednesday, Dec 05, 2012, 8:45am
Rating: | Views: 1215 | Comments: 0
Transposable elements reveal a stem cell specific class of long noncoding RNAs
Over a decade after sequencing the human genome, it has now become clear that the genome is not mostly 'junk' as previously thought. In fact, the ENCODE project consortium of dozens of labs and petabytes of data have determined that these 'noncoding' regions house everything from disease trait loci to important regulatory signals, all the way through to new types of RNA-based genes.
Over a decade after sequencing the human genome, it has now become clear that the genome is not mostly 'junk' as previously thought. In fact, the ENCODE project consortium of dozens of labs and petabytes of data have determined that these 'noncoding' regions house everything from disease trait loci to important regulatory signals, all the way through to new types of RNA-based genes.
Molecular Biology
Source: BioMed Central
Posted on: Tuesday, Nov 27, 2012, 1:00pm
Rating: | Views: 1182 | Comments: 0
Source: BioMed Central
Posted on: Tuesday, Nov 27, 2012, 1:00pm
Rating: | Views: 1182 | Comments: 0
A novel therapeutic advancement in the search for heart muscle progenitor cells
CPCs, which are typically only found in fetal development, can become all of the different cell types of the heart and can integrate into heart muscle tissue after injection.
CPCs, which are typically only found in fetal development, can become all of the different cell types of the heart and can integrate into heart muscle tissue after injection.
Stem cells
Source: Fraunhofer-Gesellschaft
Posted on: Tuesday, Nov 27, 2012, 12:00pm
Rating: | Views: 5693 | Comments: 0
Source: Fraunhofer-Gesellschaft
Posted on: Tuesday, Nov 27, 2012, 12:00pm
Rating: | Views: 5693 | Comments: 0
Body may be able to 'coach' transplanted stem cells to differentiate appropriately
Pluripotent stem cells are nature's double-edged sword. Because they can develop into a dizzying variety of cell types and tissues, they are a potentially invaluable therapeutic resource. However, that same developmental flexibility can lead to dangerous tumors called teratomas if the stem cells begin to differentiate out of control in the body.
Pluripotent stem cells are nature's double-edged sword. Because they can develop into a dizzying variety of cell types and tissues, they are a potentially invaluable therapeutic resource. However, that same developmental flexibility can lead to dangerous tumors called teratomas if the stem cells begin to differentiate out of control in the body.
Stem cells
Source: Stanford University Medical Center
Posted on: Wednesday, Nov 21, 2012, 8:15am
Rating: | Views: 1193 | Comments: 0
Source: Stanford University Medical Center
Posted on: Wednesday, Nov 21, 2012, 8:15am
Rating: | Views: 1193 | Comments: 0
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