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Et tu Odysseyus?
Tuesday, January 11, 2011
2010 (37)
December (5)

First most influential paper
Tuesday, December 14, 2010

Twelve (minus one) Months of pondering Blather
Tuesday, December 7, 2010

I'll save Tideliar the trouble
Tuesday, December 7, 2010

Thinking differently
Friday, December 3, 2010

Music Warz! - The Maccabees
Thursday, December 2, 2010
November (6)

Standing out in a crowd: An addendum
Monday, November 8, 2010

Standing out in a crowd
Friday, November 5, 2010

Ripping your arms off
Tuesday, November 2, 2010

The Tea Party explained
Tuesday, November 2, 2010

Words of wisdom for prospective graduate students
Monday, November 1, 2010

Grant advice
Monday, November 1, 2010
October (10)

Planet of the Apes
Wednesday, October 27, 2010

Too many postdocs?
Tuesday, October 26, 2010

Oh! Rats! [UPDATED]
Thursday, October 21, 2010

Rethinking Education
Monday, October 18, 2010

Elephant man, rabies and leprosy
Wednesday, October 13, 2010

Over-priced mochas and syphilis
Sunday, October 10, 2010

DonorsChoose - give early and give often. [UPDATED]
Friday, October 8, 2010

Wednesday, October 6, 2010

What I would be doing if I weren't doing science
Tuesday, October 5, 2010

Time spent reviewing
Monday, October 4, 2010
September (6)

Dear PI's who wrote the NSF proposals I am now reviewing...
Wednesday, September 29, 2010

Funding Illusions
Tuesday, September 28, 2010

FIve years ago today
Wednesday, September 22, 2010

A (temporary) cure for vortices of suckitude
Wednesday, September 15, 2010

Things that make Odyssey grumpy
Tuesday, September 14, 2010

What I wish I knew before starting my faculty position
Tuesday, September 7, 2010
August (10)

Flying 101
Tuesday, August 24, 2010

Don't panic!
Monday, August 23, 2010

One to Rule Them All
Friday, August 20, 2010

The NSF review panel process
Thursday, August 19, 2010

Peer review, schmeer review
Friday, August 13, 2010

Hypotheses: The most disposable of lab supplies
Thursday, August 12, 2010

How much do you need to want it?
Monday, August 9, 2010

Sunday, August 8, 2010

REPOST: How Many Papers for Tenure?
Thursday, August 5, 2010

Checking it out
Thursday, August 5, 2010
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I'm a molecular biophysicist in a biochemistry department. In a college of medicine. And I'm funded by the NSF. Not too sure my dean likes that... I'm here to blather on about things that interest me and to raise the average age of the bloggers here by at least 1.2567 years. And I'm Australian.

My posts are presented as opinion and commentary and do not represent the views of LabSpaces Productions, LLC, my employer, or my educational institution.

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Haha the comment above is funny! Research before hypothesis! . . .Read More
Aug 09, 2012, 1:48pm
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Good article! "Do proponents of this system have any idea just how hard it is to find reviewers under the current system?" I've just stumbled across this artcile, so my comments are. . .Read More
Oct 13, 2011, 5:20pm
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Thursday, August 12, 2010

We put so much effort into crafting our hypotheses. Carefully collecting our data. Collating. Analyzing.

Considering. Pondering. Thinking.

For hours. Days. Weeks. Months.

Even years.

Finally sculpting.

Behold you unwashed masses! We present to you a thing of great beauty and wonder-

A new hypothesis!

Bow down and worship it's awesomeness!!!

Is it any wonder that some scientists have such a hard time discarding their pet hypotheses? Or refuse to discard them at all, even in the face of overwhelming evidence that they are wrong?

I'd be willing to bet we all know someone like that.


But not excusable.

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Blog Comments

Brian Krueger, PhD
Columbia University Medical Center
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Line breaks are put in for you automatically between paragraphs. If you're using HTML, be sure there are no carriage returns in your post, otherwise you'll get double the spacing :)

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I was after the double spacing-like effect. :-)

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Bravo! Hypotheses are meant to be disproven, even if they are pretty.

Dr. O
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I live in the lab by the belief that I should be doing experiments to disprove my hypotheses, not prove them.

Bob O'H
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But remember, a pet hypothesis is for life, not just for Christmas.
Prof-like Substance

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Dude, don't you know that it is sooooo much easier to come up with the hypothesis after you have your data?

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Dude, don't you know that it is sooooo much easier to come up with the hypothesis after you have your data?

Shhhh! You're giving away my secret!

Professor in Training
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Hypothesis? Isn't that something you write to appease grant and manuscript reviewers?

biochem belle
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This post might just be printed and left in a conspicuous place for a particular PI to find after I depart the lab. (Probably not, but I do like to fantasize.)

Of course, if you're doing "discovery-driven" research (e.g. anythingomics), you don't really need this so-called hypothesis.

biochem belle
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Dr. O said:
One of the strongest memories/impressions from a conference I have is Sir Alan Fersht standing before a room of hundreds of scientists saying the way he was trained is that you developed a hypothesis and set out to falsify your hypothesis... and that it didn't mean your hypothesis was true just because you couldn't disprove it. He also made a comment along the lines that this isn't how most science is done today. It was definitely ranty and totally awesome. So awesome that I included his point when I presented my conference report to my lab (not the lab referred to in the above comment, unfortunately).
Cole Parmer

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Haha the comment above is funny! Research before hypothesis!

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