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Gebhart Lab
Lab Information
University of Pittsburgh
Address:Pittsburgh, PA USAKeywords:
visceral, central sensitization, hyperalgesia, inflammatory pain
Lab Description:
Pain: mechanisms, physiology, and pharmacology. mostly visceral (bladder, stomach, colon), but also central senstization, and descending facilitaton and inhibition.
Lab Members (1) See all?
Bielefeldt K, Lamb K, Gebhart GF. 2006. Convergence of sensory pathways in the development of somatic and visceral hypersensitivity.Am J Physiol Gastrointest Liver Physiol. 291:G658-65
Lambk K, Zhong F, Gebhart GF, Bielefeldt K.. 2006. Experimental colitis in mice and sensitization of converging visceral and somatic afferent pathways..Am J Physiol Gastrointest Liver Physiol. 290:G451-457
Lamb K, Gebhart GF, Bielefeldt K. 2006. Luminal Stimuli Acutely Sensitize Visceromotor Responses to Distension of the Rat Stomach.Digestive Disease Science. 0:XXX
Kang YM, Lamb K, Gebhart GF, Bielefeldt K.. 2005. Experimentally induced ulcers and gastric sensory-motor function in rats..Am J Physiol Gastrointest Liver Physiol.. 288:G284-291
Dang K, Bielefeldt K, Lamb K, Gebhart GF.. 2005. Gastric ulcers evoke hyperexcitability and enhance P2X receptor function in rat gastric sensory neurons.J Neurophysiol.. 93:3112-3119
Sugiura T, Dang K, Lamb K, Bielefeldt K, Gebhart GF.. 2005. Acid-sensing properties in rat gastric sensory neurons from normal and ulcerated stomach.J Neurosci. 25:2617-2627
Lamb K, Gebhart GF, Bielefeldt K. 2004. Increased nerve growth factor expression triggers bladder overactivity..Journal of Pain. 5:150-56
Lamb K, Bielefeldt K.. 2003. Rapid effects of neurotrophic factors on calcium homeostasis in rat visceral afferent neurons.Neurosci Lett. 336:9-12
Lamb K, Kang YM, Gebhart GF, Bielefeldt K.. 2003. Nerve growth factor and gastric hyperalgesia in the rat..Neurogastroenterol Motil. 15:355-61
Joshi S, Lambk K, Bielefeldt K, Gebhart GF. 2003. Arylacetamide kappa-opioid receptor agonists produce a tonic- and use-dependent block of tetrodotoxin-sensitive and -resistant sodium currents in colon sensory neurons.J Pharmacol Exp Ther.. 307:367-72
Lamb K, Kang YM, Gebhart GF, Bielefeldt K.. 2003. Gastric inflammation triggers hypersensitivity to acid in awake rats.Gastroenterology. 125:1410-8