Gebhart Lab
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Lab Information
University of Pittsburgh Department:
AnesthesiaAddress:Pittsburgh, PA USAKeywords:
visceral, central sensitization, hyperalgesia, inflammatory painLab Description:
Pain: mechanisms, physiology, and pharmacology. mostly visceral (bladder, stomach, colon), but also central senstization, and descending facilitaton and inhibition.
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Lab Members (1) See all?
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Publications
Lambk K, Zhong F, Gebhart GF, Bielefeldt K.. 2006. Experimental colitis in mice and sensitization of converging visceral and somatic afferent pathways..Am J Physiol Gastrointest Liver Physiol. 290:G451-457
Lamb K, Gebhart GF, Bielefeldt K. 2006. Luminal Stimuli Acutely Sensitize Visceromotor Responses to Distension of the Rat Stomach.Digestive Disease Science. 0:XXX
Bielefeldt K, Lamb K, Gebhart GF. 2006. Convergence of sensory pathways in the development of somatic and visceral hypersensitivity.Am J Physiol Gastrointest Liver Physiol. 291:G658-65
Dang K, Bielefeldt K, Lamb K, Gebhart GF.. 2005. Gastric ulcers evoke hyperexcitability and enhance P2X receptor function in rat gastric sensory neurons.J Neurophysiol.. 93:3112-3119
Sugiura T, Dang K, Lamb K, Bielefeldt K, Gebhart GF.. 2005. Acid-sensing properties in rat gastric sensory neurons from normal and ulcerated stomach.J Neurosci. 25:2617-2627
Kang YM, Lamb K, Gebhart GF, Bielefeldt K.. 2005. Experimentally induced ulcers and gastric sensory-motor function in rats..Am J Physiol Gastrointest Liver Physiol.. 288:G284-291
Lamb K, Gebhart GF, Bielefeldt K. 2004. Increased nerve growth factor expression triggers bladder overactivity..Journal of Pain. 5:150-56
Lamb K, Bielefeldt K.. 2003. Rapid effects of neurotrophic factors on calcium homeostasis in rat visceral afferent neurons.Neurosci Lett. 336:9-12
Lamb K, Kang YM, Gebhart GF, Bielefeldt K.. 2003. Nerve growth factor and gastric hyperalgesia in the rat..Neurogastroenterol Motil. 15:355-61
Joshi S, Lambk K, Bielefeldt K, Gebhart GF. 2003. Arylacetamide kappa-opioid receptor agonists produce a tonic- and use-dependent block of tetrodotoxin-sensitive and -resistant sodium currents in colon sensory neurons.J Pharmacol Exp Ther.. 307:367-72
Lamb K, Kang YM, Gebhart GF, Bielefeldt K.. 2003. Gastric inflammation triggers hypersensitivity to acid in awake rats.Gastroenterology. 125:1410-8
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