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Blocking stem-loop with Morpholino stops asymmetric RNA segregation

Jon Moulton
Gene Tools, LLC
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Blocking stem-loop with Morpholino stops asymmetric RNA segregation
Wed, Nov 03, 2010, 1:51 pm CDT

Rabinowitz JS, Lambert JD. Spiralian quartet developmental potential is regulated by specific localization elements that mediate asymmetric RNA segregation. Development. 2010 Nov 1. [Epub ahead of print]


Invading an RNA stem-loop with a complementary Morpholino prevents asymmetric RNA segregation in the developing Ilyanassa obligata snail. “Our characterization of this structure and a similar one from another first quartet RNA suggests a model for how first quartet specificity is achieved.”


Blocking stem-loop with Morpholino stops asymmetric RNA segregation
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