Aging takes its toll on sex appeal and now an international team of researchers led by Baylor College of Medicine and the University of Michigan find that in fruit flies, at least, it even diminishes the come-hither effect of the chemicals of love – pheromones.
"This is new because we have direct evidence that the pheromones produced at these different ages affect sexual attractiveness differently," said Tsung-Han Kuo, a graduate student in the department of molecular and human genetics and the Huffington Center on Aging at BCM. Kuo is first author of the report that appears online in the Journal of Experimental Biology.
Pheromones are chemicals produced by an organism to communicate or attract another. In this case, Drosophila melanogaster or fruit flies produce chemicals called cuticular hydrocarbons. Special mass spectrometry studies that looked in detail at the composition and level of production of these hydrocarbons showed that they differed between the sexes, but more important, they changed with age.
"In fact, cuticular hydrocarbon production may be an indicator of the insect's health and fertility," said Kuo. Reproduction is one of the major activities of the short-lived insects, and they enhance the possibility of passing on their genes through the production of these pheromones. Unfortunately, the alluring effect of the chemicals wanes with age.
"The results were remarkably consistent across different strains of flies," said Dr. Scott Pletcher, now of the University of Michigan, and Kuo's initial mentor at BCM.
Kuo, Pletcher and Dr. Herman A. Dierick, assistant professor of molecular and human genetics at BCM, then determined how the pheromones produced at different ages affected the attractiveness of the fruit flies.
Using a specially designed holding cell, Kuo introduced a male fly into a chamber that contained two females – a young fly and an old fly. Video of the encounter showed that the male was much more attracted to the young fly.
To eliminate physical appearance from the equation, he then conducted the experiment in the dark. The males still courted the young females more vigorously. When the scientists washed the pheromones off the females' bodies, the males could no longer tell a difference between young and old.
"In the last analysis, we took the pheromone from the young and old flies and put it on flies that do not produce pheromones," said Kuo. "The flies were identical in every way but the males still preferred the flies with the 'younger' pheromone."
"We know that aging is conserved across species," said Pletcher. "We want to examine the exciting possibility that the mechanisms underlying attractiveness are also conserved across species."
Baylor College of Medicine: http://www.bcm.edu/news/mediacenter
This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.
Rising temperatures and a more acidic ocean may spell trouble for the Chesapeake Bay's iconic crabs, oysters and fish
Huge specimen caught in Antarctic waters by New Zealand fishing crew is one of few ever examined
Lonesome George, the worlds most famous tortoise, goes on display at the American Museum of Natural History.
Oxytricha trifallax lives in ponds all over the world. Under an electron microscope it looks like a football adorned with tassels. The tiny fringes are the cilia it uses to move around and gobble up algae. What makes Oxytricha unusual, however, is the crazy things it does with its DNA.
A Japanese woman with macular degeneration is the first person to be treated with induced pluripotent stem cells, made from her own skin
A DNA sequencer the size of a cell phone could change where, and how, gene research occurs.One day in 1989, biophysicist David Deamer pulled his car off California’s Interstate 5 to hurriedly scribble down an idea. In a mental flash, he had pictured a strand of DNA threading its way through a microscopic pore. Grabbing a pen and a yellow pad, he sketched out a radical new way to study the molecule of life.
New research led by the University of Leicester in the U.K. gives a blow-by-blow account of the injuries inflicted on King Richard III at the Battle of Bosworth Field on Aug 22, 1485. Modern forensic analysis of the King’s skeletal remains reveals that three of his injuries had the potential to cause death quickly.
Look into the jaws of a Mosasaurus and you will gaze into a nightmare.
Although it's far from the sort of brain transplant beloved by science fiction enthusiasts, scientists have taken one step in that direction: they have spliced a key human brain gene into mice.
A network in the brain that helps control daydreaming seem to be slower to develop in children with attention deficit hyperactivity disorder.