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Mayo researchers discover how measles virus spreads in its host 
Measles, one of the most common contagious diseases, has been thought to enter the body through the surface of airways and lungs, like many other major viruses. Now, Mayo Clinic researchers and their collaborators say that's not the case, and some medical texts will have to be revised.
Measles, one of the most common contagious diseases, has been thought to enter the body through the surface of airways and lungs, like many other major viruses. Now, Mayo Clinic researchers and their collaborators say that's not the case, and some medical texts will have to be revised.
Immunology
Source: Mayo Clinic
Posted on: Friday, Jun 20, 2008, 5:01pm
Rating: | Views: 1416 | Comments: 0
Source: Mayo Clinic
Posted on: Friday, Jun 20, 2008, 5:01pm
Rating: | Views: 1416 | Comments: 0
Researchers discover Legionnaire microbe's tricks
Yale University researchers have shed new light how bacteria like the ones that cause Legionnaires' disease and Q-fever raise such havoc in human patients.
Yale University researchers have shed new light how bacteria like the ones that cause Legionnaires' disease and Q-fever raise such havoc in human patients.
Immunology
Source: Yale University
Posted on: Friday, Jun 20, 2008, 9:05am
Rating: | Views: 1589 | Comments: 0
Source: Yale University
Posted on: Friday, Jun 20, 2008, 9:05am
Rating: | Views: 1589 | Comments: 0
Scientists find potential new way to block inflammation in autoimmune disease
Scientists have identified a promising new target for autoimmune disease treatment – a cell-surface receptor called DR3. Their research in mice suggests that blocking this receptor could slow or stop the damaging inflammation characteristic of autoimmune diseases, potentially without leaving the body vulnerable to serious infections, as many current therapies do.
Scientists have identified a promising new target for autoimmune disease treatment – a cell-surface receptor called DR3. Their research in mice suggests that blocking this receptor could slow or stop the damaging inflammation characteristic of autoimmune diseases, potentially without leaving the body vulnerable to serious infections, as many current therapies do.
Immunology
Source: NIH/National Institute of Arthritis and Musculoskeletal and Skin Diseases
Posted on: Thursday, Jun 19, 2008, 11:32am
Rating: | Views: 1232 | Comments: 0
Source: NIH/National Institute of Arthritis and Musculoskeletal and Skin Diseases
Posted on: Thursday, Jun 19, 2008, 11:32am
Rating: | Views: 1232 | Comments: 0
New findings on immune system in amphibians
Unlike mammals, not much has been known until now about the immune defence of amphibians. Globally, amphibian populations are in an unprecedented decline, to a considerable extent caused by rapidly spreading infectious diseases, such as the fungal infection Chytridiomycosis. Therefore future conservation strategies for amphibians could benefit from knowledge about species-specific adaptations
Unlike mammals, not much has been known until now about the immune defence of amphibians. Globally, amphibian populations are in an unprecedented decline, to a considerable extent caused by rapidly spreading infectious diseases, such as the fungal infection Chytridiomycosis. Therefore future conservation strategies for amphibians could benefit from knowledge about species-specific adaptations
Immunology
Source: Helmholtz Association of German Research Centres
Posted on: Thursday, Jun 19, 2008, 10:33am
Rating: | Views: 1235 | Comments: 0
Source: Helmholtz Association of German Research Centres
Posted on: Thursday, Jun 19, 2008, 10:33am
Rating: | Views: 1235 | Comments: 0
Cloned T cells kill melanoma tumors
Researchers describe the first successful use of a human patient's cloned infection-fighting T cells as the sole therapy to put an advanced solid-tumor cancer into long-term remission. A team led by Cassian Yee, M.D., an associate member of the Clinical Research Division at Fred Hutchinson Cancer Research Center, reports these findings in the June 19 issue of the New England Journal of Medicine.
Researchers describe the first successful use of a human patient's cloned infection-fighting T cells as the sole therapy to put an advanced solid-tumor cancer into long-term remission. A team led by Cassian Yee, M.D., an associate member of the Clinical Research Division at Fred Hutchinson Cancer Research Center, reports these findings in the June 19 issue of the New England Journal of Medicine.
Immunology
Source: Fred Hutchinson Cancer Research Center
Posted on: Wednesday, Jun 18, 2008, 5:12pm
Rating: | Views: 3989 | Comments: 0
Source: Fred Hutchinson Cancer Research Center
Posted on: Wednesday, Jun 18, 2008, 5:12pm
Rating: | Views: 3989 | Comments: 0
Immune molecule that plays a powerful role in avoiding organ rejection identified
When a mouse's immune system is deciding whether to reject a skin graft, one powerful member of a molecular family designed to provoke such a response can effectively reduce the visibility of the mouse's own cells and help the graft survive, researchers say.
When a mouse's immune system is deciding whether to reject a skin graft, one powerful member of a molecular family designed to provoke such a response can effectively reduce the visibility of the mouse's own cells and help the graft survive, researchers say.
Immunology
Source: Medical College of Georgia
Posted on: Monday, Jun 16, 2008, 2:49pm
Rating: | Views: 1236 | Comments: 0
Source: Medical College of Georgia
Posted on: Monday, Jun 16, 2008, 2:49pm
Rating: | Views: 1236 | Comments: 0
Anti-inflammatory effects of pomegranate
Oral ingestion of pomegranate extract reduces the production of chemicals that cause inflammation suggests a study published in BioMed Central's open access Journal of Inflammation. The findings indicate that pomegranate extract may provide humans with relief of chronic inflammatory conditions.
Oral ingestion of pomegranate extract reduces the production of chemicals that cause inflammation suggests a study published in BioMed Central's open access Journal of Inflammation. The findings indicate that pomegranate extract may provide humans with relief of chronic inflammatory conditions.
Immunology
Source: BioMed Central
Posted on: Friday, Jun 13, 2008, 10:04am
Rating: | Views: 1581 | Comments: 0
Source: BioMed Central
Posted on: Friday, Jun 13, 2008, 10:04am
Rating: | Views: 1581 | Comments: 0
Ancient antibody molecule offers clues to how humans evolved allergies
Scientists have discovered how evolution may have lumbered humans with allergy problems. They have discovered that chicken antibodies behaves quite differently from its human counterpart, which throws light on the origin and cause of allergic reactions in humans and gives hope for new strategies for treatment.
Scientists have discovered how evolution may have lumbered humans with allergy problems. They have discovered that chicken antibodies behaves quite differently from its human counterpart, which throws light on the origin and cause of allergic reactions in humans and gives hope for new strategies for treatment.
Immunology
Source: Biotechnology and Biological Sciences Research Council
Posted on: Friday, Jun 13, 2008, 9:50am
Rating: | Views: 1248 | Comments: 0
Source: Biotechnology and Biological Sciences Research Council
Posted on: Friday, Jun 13, 2008, 9:50am
Rating: | Views: 1248 | Comments: 0
Cell surface receptors are all 'talk' in T cell stimulation
nderstanding the mechanisms that drive healthy immune responses is important when it comes to combating autoimmune diseases, which occur when cells that should attack invading organisms turn on the body instead.
nderstanding the mechanisms that drive healthy immune responses is important when it comes to combating autoimmune diseases, which occur when cells that should attack invading organisms turn on the body instead.
Immunology
Source: Tufts University, Health Sciences
Posted on: Thursday, Jun 12, 2008, 11:41am
Rating: | Views: 1201 | Comments: 0
Source: Tufts University, Health Sciences
Posted on: Thursday, Jun 12, 2008, 11:41am
Rating: | Views: 1201 | Comments: 0
Cancer-killing viruses influence tumor blood-vessel growth
Viruses genetically designed to kill cancer cells offer a promising strategy for treating incurable brain tumors such as glioblastoma, but the body's natural defenses often eliminate the viruses before they can eliminate the tumor.
Viruses genetically designed to kill cancer cells offer a promising strategy for treating incurable brain tumors such as glioblastoma, but the body's natural defenses often eliminate the viruses before they can eliminate the tumor.
Immunology
Source: Ohio State University Medical Center
Posted on: Tuesday, Jun 10, 2008, 4:46pm
Rating: | Views: 1211 | Comments: 0
Source: Ohio State University Medical Center
Posted on: Tuesday, Jun 10, 2008, 4:46pm
Rating: | Views: 1211 | Comments: 0
'HiCy' drug regimen reverses ms symptoms in selected patients
A short-term, very-high dose regimen of the immune-suppressing drug cyclophosphamide seems to slow progression of multiple sclerosis (MS) in most of a small group of patients studied and may even restore neurological function lost to the disease, Johns Hopkins researchers report.
A short-term, very-high dose regimen of the immune-suppressing drug cyclophosphamide seems to slow progression of multiple sclerosis (MS) in most of a small group of patients studied and may even restore neurological function lost to the disease, Johns Hopkins researchers report.
Immunology
Source: Johns Hopkins Medical Institutions
Posted on: Tuesday, Jun 10, 2008, 11:24am
Rating: | Views: 1334 | Comments: 0
Source: Johns Hopkins Medical Institutions
Posted on: Tuesday, Jun 10, 2008, 11:24am
Rating: | Views: 1334 | Comments: 0
researchers develop new PET scanning probe that will allow monitoring of the immune system
Researchers at UCLA's Jonsson Comprehensive Cancer Center have modified a common chemotherapy drug to create a new probe for Positron Emission Tomography (PET), an advance that will allow them to model and measure the immune system in action and monitor response to new therapies.
Researchers at UCLA's Jonsson Comprehensive Cancer Center have modified a common chemotherapy drug to create a new probe for Positron Emission Tomography (PET), an advance that will allow them to model and measure the immune system in action and monitor response to new therapies.
Immunology
Source: University of California - Los Angeles
Posted on: Monday, Jun 09, 2008, 8:50am
Rating: | Views: 1155 | Comments: 0
Source: University of California - Los Angeles
Posted on: Monday, Jun 09, 2008, 8:50am
Rating: | Views: 1155 | Comments: 0
Researchers clear up Alzheimer's plaques in mice
Blocking a common immune system response cleared up plaques associated with Alzheimer’s Disease and enabled treated mice to recover some lost memory, Yale University researchers report Friday in the journal Nature Medicine.
Blocking a common immune system response cleared up plaques associated with Alzheimer’s Disease and enabled treated mice to recover some lost memory, Yale University researchers report Friday in the journal Nature Medicine.
Immunology
Source: EurekAlert
Posted on: Friday, May 30, 2008, 12:49pm
Rating: | Views: 1348 | Comments: 0
Source: EurekAlert
Posted on: Friday, May 30, 2008, 12:49pm
Rating: | Views: 1348 | Comments: 0
New West Nile and Japanese encephalitis vaccines produced
University of Texas Medical Branch at Galveston researchers have developed new vaccines to protect against West Nile and Japanese encephalitis viruses. The investigators created the vaccines using an innovative technique that they believe could also enable the development of new vaccines against other diseases, such as yellow fever and dengue fever, which are caused by similar viruses.
University of Texas Medical Branch at Galveston researchers have developed new vaccines to protect against West Nile and Japanese encephalitis viruses. The investigators created the vaccines using an innovative technique that they believe could also enable the development of new vaccines against other diseases, such as yellow fever and dengue fever, which are caused by similar viruses.
Immunology
Source: EurekAlert
Posted on: Friday, May 30, 2008, 10:02am
Rating: | Views: 1178 | Comments: 0
Source: EurekAlert
Posted on: Friday, May 30, 2008, 10:02am
Rating: | Views: 1178 | Comments: 0
Regulatory B cells exist -- and pack a punch
Researchers at Duke University Medical Center have uncovered definitive evidence that a small but potent subset of immune system B cells is able to regulate inflammation.
Researchers at Duke University Medical Center have uncovered definitive evidence that a small but potent subset of immune system B cells is able to regulate inflammation.
Immunology
Source: EurekAlert
Posted on: Tuesday, May 27, 2008, 3:46pm
Rating: | Views: 1142 | Comments: 0
Source: EurekAlert
Posted on: Tuesday, May 27, 2008, 3:46pm
Rating: | Views: 1142 | Comments: 0
'Intrabody' can mop up mutant protein in Huntington's disease model
Scientists have created a tool for mopping up the clumps of mutant protein that drive neurodegeneration in Huntington's disease. Emory University researchers engineered a virus to make an intracellular antibody or "intrabody" against huntingtin, the protein whose mutant forms poison the brain cells of people with Huntington's.
Scientists have created a tool for mopping up the clumps of mutant protein that drive neurodegeneration in Huntington's disease. Emory University researchers engineered a virus to make an intracellular antibody or "intrabody" against huntingtin, the protein whose mutant forms poison the brain cells of people with Huntington's.
Immunology
Source: EurekAlert
Posted on: Tuesday, May 27, 2008, 8:30am
Rating: | Views: 1135 | Comments: 0
Source: EurekAlert
Posted on: Tuesday, May 27, 2008, 8:30am
Rating: | Views: 1135 | Comments: 0
Scientists discover how common vaccine booster works
n an online paper in the journal Nature, Yale University researchers explain how a common ingredient in many vaccines stimulates and interacts with the immune system to help provide protection against infectious diseases.
n an online paper in the journal Nature, Yale University researchers explain how a common ingredient in many vaccines stimulates and interacts with the immune system to help provide protection against infectious diseases.
Immunology
Source: EurekAlert
Posted on: Wednesday, May 21, 2008, 5:02pm
Rating: | Views: 1190 | Comments: 0
Source: EurekAlert
Posted on: Wednesday, May 21, 2008, 5:02pm
Rating: | Views: 1190 | Comments: 0
Family history may be associated with susceptibility to shingles
Individuals with herpes zoster, or shingles, are more likely to report a family history of the condition, according to a report in the May issue of Archives of Dermatology, one of the JAMA/Archives journals.
Individuals with herpes zoster, or shingles, are more likely to report a family history of the condition, according to a report in the May issue of Archives of Dermatology, one of the JAMA/Archives journals.
Immunology
Source: EurekAlert
Posted on: Monday, May 19, 2008, 3:28pm
Rating: | Views: 1214 | Comments: 0
Source: EurekAlert
Posted on: Monday, May 19, 2008, 3:28pm
Rating: | Views: 1214 | Comments: 0
Vaccine triggers immune response, prevents Alzheimer's
A vaccine created by University of Rochester Medical Center scientists prevents the development of Alzheimer’s disease-like pathology in mice without causing inflammation or significant side effects.
A vaccine created by University of Rochester Medical Center scientists prevents the development of Alzheimer’s disease-like pathology in mice without causing inflammation or significant side effects.
Immunology
Source: EurekAlert
Posted on: Monday, May 19, 2008, 10:53am
Rating: | Views: 1639 | Comments: 0
Source: EurekAlert
Posted on: Monday, May 19, 2008, 10:53am
Rating: | Views: 1639 | Comments: 0
New vaccine for meningitis B shows promise
Oxford researchers are part of a team reporting encouraging results in a clinical trial of a new meningitis vaccine at a conference in Austria this week.
Oxford researchers are part of a team reporting encouraging results in a clinical trial of a new meningitis vaccine at a conference in Austria this week.
Immunology
Source: University of Oxford
Posted on: Friday, May 16, 2008, 9:43am
Rating: | Views: 1212 | Comments: 0
Source: University of Oxford
Posted on: Friday, May 16, 2008, 9:43am
Rating: | Views: 1212 | Comments: 0
HIV infection stems from few viruses
A new study reveals the genetic identity of human immunodeficiency virus (HIV), the version responsible for sexual transmission, in unprecedented detail.
A new study reveals the genetic identity of human immunodeficiency virus (HIV), the version responsible for sexual transmission, in unprecedented detail.
Immunology
Source: EurekAlert
Posted on: Friday, May 16, 2008, 9:06am
Rating: | Views: 1194 | Comments: 0
Source: EurekAlert
Posted on: Friday, May 16, 2008, 9:06am
Rating: | Views: 1194 | Comments: 0
Immune cells kill foes by disrupting mitochondria 2 ways
When killer T cells of the immune system encounter virus-infected or cancer cells, they unload a lethal mix of toxic proteins that trigger the target cells to self-destruct. A new study shows T cells can initiate cellular suicide, also known as programmed cell death or apoptosis, by a previously unrecognized pathway that starts with the destruction of a key enzyme in mitochondria
When killer T cells of the immune system encounter virus-infected or cancer cells, they unload a lethal mix of toxic proteins that trigger the target cells to self-destruct. A new study shows T cells can initiate cellular suicide, also known as programmed cell death or apoptosis, by a previously unrecognized pathway that starts with the destruction of a key enzyme in mitochondria
Immunology
Source: EurekAlert
Posted on: Thursday, May 15, 2008, 11:50am
Rating: | Views: 1159 | Comments: 0
Source: EurekAlert
Posted on: Thursday, May 15, 2008, 11:50am
Rating: | Views: 1159 | Comments: 0
Dr. Anthony Fauci reflects on 25 years of HIV
On the 25th anniversary of the first scientific article linking a retrovirus to AIDS, Anthony S. Fauci, M.D., director of the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, reflects in an essay in Nature on his experience treating and studying HIV/AIDS for the past quarter century.
On the 25th anniversary of the first scientific article linking a retrovirus to AIDS, Anthony S. Fauci, M.D., director of the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, reflects in an essay in Nature on his experience treating and studying HIV/AIDS for the past quarter century.
Immunology
Source: EurekAlert
Posted on: Thursday, May 15, 2008, 11:07am
Rating: | Views: 1184 | Comments: 0
Source: EurekAlert
Posted on: Thursday, May 15, 2008, 11:07am
Rating: | Views: 1184 | Comments: 0
Learning from death
Vishva Dixit's study of cellular demise led to the discovery of a new molecular-signalling mechanism — one with implications for inflammation and perhaps much more, reports Melinda Wenner.
Vishva Dixit's study of cellular demise led to the discovery of a new molecular-signalling mechanism — one with implications for inflammation and perhaps much more, reports Melinda Wenner.
Immunology
Source: Nature
Posted on: Thursday, May 15, 2008, 10:16am
Rating: | Views: 1532 | Comments: 0
Source: Nature
Posted on: Thursday, May 15, 2008, 10:16am
Rating: | Views: 1532 | Comments: 0
Researchers Get Inside a Long-suspected HIV Hideout in Humans
A new study shows infectious HIV hides out during drug treatments in a third type of reservoir cell. Called FDCs, these cells act as bank vaults storing material necessary to maintain the immune system’s armies of antibodies. This advance will help the medical community figure out how to attack virus hidden by the reservoir cells.
A new study shows infectious HIV hides out during drug treatments in a third type of reservoir cell. Called FDCs, these cells act as bank vaults storing material necessary to maintain the immune system’s armies of antibodies. This advance will help the medical community figure out how to attack virus hidden by the reservoir cells.
Immunology
Source: Newswise
Posted on: Tuesday, May 13, 2008, 4:45pm
Rating: | Views: 1184 | Comments: 0
Source: Newswise
Posted on: Tuesday, May 13, 2008, 4:45pm
Rating: | Views: 1184 | Comments: 0
Air pollution, smoking affect latent tuberculosis
A toxic gas present in air pollution and tobacco smoke plays a significant role in triggering tuberculosis infection, according to a new study from researchers at the University of Alabama at Birmingham (UAB).
A toxic gas present in air pollution and tobacco smoke plays a significant role in triggering tuberculosis infection, according to a new study from researchers at the University of Alabama at Birmingham (UAB).
Immunology
Source: EurekAlert
Posted on: Tuesday, May 13, 2008, 9:09am
Rating: | Views: 1150 | Comments: 0
Source: EurekAlert
Posted on: Tuesday, May 13, 2008, 9:09am
Rating: | Views: 1150 | Comments: 0
Study shows how T cell's machinery dials down autoimmunity
A St. Jude Children’s Research Hospital study shows that T cells, the body’s master immune regulators, do not use simple on/off switches to govern the cellular machinery that regulates their development and function. Rather, they possess sophisticated molecular controls that enable them to adjust their function with exquisite precision.
A St. Jude Children’s Research Hospital study shows that T cells, the body’s master immune regulators, do not use simple on/off switches to govern the cellular machinery that regulates their development and function. Rather, they possess sophisticated molecular controls that enable them to adjust their function with exquisite precision.
Immunology
Source: EurekAlert
Posted on: Monday, May 12, 2008, 12:29pm
Rating: | Views: 1190 | Comments: 0
Source: EurekAlert
Posted on: Monday, May 12, 2008, 12:29pm
Rating: | Views: 1190 | Comments: 0
Suspected cause of type 1 diabetes caught 'red-handed' for the first time
Scientists at Washington University School of Medicine in St. Louis working with diabetic mice have examined in unprecedented detail the immune cells long thought to be responsible for type 1 diabetes.
Scientists at Washington University School of Medicine in St. Louis working with diabetic mice have examined in unprecedented detail the immune cells long thought to be responsible for type 1 diabetes.
Immunology
Source: EurekAlert
Posted on: Friday, May 09, 2008, 10:46am
Rating: | Views: 2181 | Comments: 0
Source: EurekAlert
Posted on: Friday, May 09, 2008, 10:46am
Rating: | Views: 2181 | Comments: 0
Immune system pathway identified to fight allergens
For the first time, researchers from the University of Pittsburgh School of Medicine have identified genetic components of dendritic cells that are key to asthma and allergy-related immune response malfunction. Targeting these elements could result in more effective drugs to treat allergic disorders and asthma, according to a study reported in the May edition of the journal Nature Medicine.
For the first time, researchers from the University of Pittsburgh School of Medicine have identified genetic components of dendritic cells that are key to asthma and allergy-related immune response malfunction. Targeting these elements could result in more effective drugs to treat allergic disorders and asthma, according to a study reported in the May edition of the journal Nature Medicine.
Immunology
Source: EurekAlert
Posted on: Wednesday, May 07, 2008, 11:52am
Rating: | Views: 1223 | Comments: 0
Source: EurekAlert
Posted on: Wednesday, May 07, 2008, 11:52am
Rating: | Views: 1223 | Comments: 0
Exhaustion of HIV-specific T cells may be caused by chronic exposure to virus
The “exhaustion” of immune cells that target HIV appears to result from chronic exposure to the virus, specifically exposure to the particular protein segments targeted by the pathogen-killing HIV-specific CD8 T cells.
The “exhaustion” of immune cells that target HIV appears to result from chronic exposure to the virus, specifically exposure to the particular protein segments targeted by the pathogen-killing HIV-specific CD8 T cells.
Immunology
Source: EurekAlert
Posted on: Tuesday, May 06, 2008, 8:52am
Rating: | Views: 1235 | Comments: 0
Source: EurekAlert
Posted on: Tuesday, May 06, 2008, 8:52am
Rating: | Views: 1235 | Comments: 0
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