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Cell scaffolding protein fascin-1 is hijacked by cancer 
A protein involved in the internal cell scaffold is associated with increased risk of metastasis and mortality in a range of common cancers finds a meta-analysis published in Biomed Central's open access journal BMC Medicine.
A protein involved in the internal cell scaffold is associated with increased risk of metastasis and mortality in a range of common cancers finds a meta-analysis published in Biomed Central's open access journal BMC Medicine.
Cancer
Source: BioMed Central
Posted on: Tuesday, Feb 26, 2013, 1:45pm
Rating: | Views: 1207 | Comments: 0
Source: BioMed Central
Posted on: Tuesday, Feb 26, 2013, 1:45pm
Rating: | Views: 1207 | Comments: 0
BPA may affect the developing brain by disrupting gene regulation
Environmental exposure to bisphenol A (BPA), a widespread chemical found in plastics and resins, may suppress a gene vital to nerve cell function and to the development of the central nervous system, according to a study led by researchers at Duke Medicine.
Environmental exposure to bisphenol A (BPA), a widespread chemical found in plastics and resins, may suppress a gene vital to nerve cell function and to the development of the central nervous system, according to a study led by researchers at Duke Medicine.
Neuroscience
Source: Duke University Medical Center
Posted on: Tuesday, Feb 26, 2013, 11:45am
Rating: | Views: 1206 | Comments: 0
Source: Duke University Medical Center
Posted on: Tuesday, Feb 26, 2013, 11:45am
Rating: | Views: 1206 | Comments: 0
Life's tiniest architects pinpointed by researchers
If a genome is the blueprint for life, then the chief architects are tiny slices of genetic material that orchestrate how we are assembled and function, Yale School of Medicine researchers report Feb. 21 in the journal Developmental Cell.
If a genome is the blueprint for life, then the chief architects are tiny slices of genetic material that orchestrate how we are assembled and function, Yale School of Medicine researchers report Feb. 21 in the journal Developmental Cell.
Molecular Biology
Source: Yale University
Posted on: Friday, Feb 22, 2013, 12:30pm
Rating: | Views: 1241 | Comments: 0
Source: Yale University
Posted on: Friday, Feb 22, 2013, 12:30pm
Rating: | Views: 1241 | Comments: 0
Mosquitoes exposed to DEET once are less repelled by it a few hours later
Mosquitoes are able to ignore the smell of the insect repellent DEET within a few hours of being exposed to it, according to research published February 20 in the open access journal PLOS ONE by James Logan, Nina Stanczyk and colleagues from the London School of Hygiene & Tropical Medicine, UK.
Mosquitoes are able to ignore the smell of the insect repellent DEET within a few hours of being exposed to it, according to research published February 20 in the open access journal PLOS ONE by James Logan, Nina Stanczyk and colleagues from the London School of Hygiene & Tropical Medicine, UK.
Chemistry
Source: Public Library of Science
Posted on: Thursday, Feb 21, 2013, 2:15pm
Rating: | Views: 1478 | Comments: 0
Source: Public Library of Science
Posted on: Thursday, Feb 21, 2013, 2:15pm
Rating: | Views: 1478 | Comments: 0
Bullied children can suffer lasting psychological harm as adults
Bullied children grow into adults who are at increased risk of developing anxiety disorders, depression and suicidal thoughts, according to a study led by researchers at Duke Medicine.
Bullied children grow into adults who are at increased risk of developing anxiety disorders, depression and suicidal thoughts, according to a study led by researchers at Duke Medicine.
Psychology
Source: Duke University Medical Center
Posted on: Thursday, Feb 21, 2013, 1:15pm
Rating: | Views: 1865 | Comments: 0
Source: Duke University Medical Center
Posted on: Thursday, Feb 21, 2013, 1:15pm
Rating: | Views: 1865 | Comments: 0
Human cognition depends upon slow-firing neurons
Good mental health and clear thinking depend upon our ability to store and manipulate thoughts on a sort of "mental sketch pad." In a new study, Yale School of Medicine researchers describe the molecular basis of this ability — the hallmark of human cognition — and describe how a breakdown of the system contributes to diseases such as schizophrenia and Alzheimer's disease.
Good mental health and clear thinking depend upon our ability to store and manipulate thoughts on a sort of "mental sketch pad." In a new study, Yale School of Medicine researchers describe the molecular basis of this ability — the hallmark of human cognition — and describe how a breakdown of the system contributes to diseases such as schizophrenia and Alzheimer's disease.
Neuroscience
Source: Yale University
Posted on: Thursday, Feb 21, 2013, 12:00pm
Rating: | Views: 1350 | Comments: 0
Source: Yale University
Posted on: Thursday, Feb 21, 2013, 12:00pm
Rating: | Views: 1350 | Comments: 0
Rewriting a receptor's role
In a pair of new papers, researchers at the University of California, San Diego School of Medicine and the Royal Netherlands Academy of Arts and Sciences upend a long-held view about the basic functioning of a key receptor molecule involved in signaling between neurons, and describe how a compound linked to Alzheimer's disease impacts that receptor and weakens synaptic connections between brain ce
In a pair of new papers, researchers at the University of California, San Diego School of Medicine and the Royal Netherlands Academy of Arts and Sciences upend a long-held view about the basic functioning of a key receptor molecule involved in signaling between neurons, and describe how a compound linked to Alzheimer's disease impacts that receptor and weakens synaptic connections between brain ce
Neuroscience
Source: University of California - San Diego
Posted on: Wednesday, Feb 20, 2013, 2:45pm
Rating: | Views: 1157 | Comments: 0
Source: University of California - San Diego
Posted on: Wednesday, Feb 20, 2013, 2:45pm
Rating: | Views: 1157 | Comments: 0
Young malaria parasites refuse to take their medicine, may explain emerging drug resistance
New research has revealed that immature malaria parasites are more resistant to treatment with key antimalarial drugs than older parasites, a finding that could lead to more effective treatments for a disease that kills one person every minute and is developing resistance to drugs at an alarming rate.
New research has revealed that immature malaria parasites are more resistant to treatment with key antimalarial drugs than older parasites, a finding that could lead to more effective treatments for a disease that kills one person every minute and is developing resistance to drugs at an alarming rate.
Molecular Biology
Source: University of Melbourne
Posted on: Tuesday, Feb 19, 2013, 12:45pm
Rating: | Views: 1429 | Comments: 0
Source: University of Melbourne
Posted on: Tuesday, Feb 19, 2013, 12:45pm
Rating: | Views: 1429 | Comments: 0
Discovery in HIV may solve efficiency problems for gene therapy
A research team from Case Western Reserve University School of Medicine has discovered an approach that could make gene therapy dramatically more effective for patients.
A research team from Case Western Reserve University School of Medicine has discovered an approach that could make gene therapy dramatically more effective for patients.
Genetics
Source: Case Western Reserve University
Posted on: Friday, Feb 15, 2013, 12:00pm
Rating: | Views: 1192 | Comments: 0
Source: Case Western Reserve University
Posted on: Friday, Feb 15, 2013, 12:00pm
Rating: | Views: 1192 | Comments: 0
Sustainable new catalysts fueled by a single proton
Chemists at Boston College have designed a new class of catalysts triggered by the charge of a single proton, the team reports in the most recent edition of the journal Nature. The simple organic molecules offer a sustainable and highly efficient platform for chemical reactions that produce sets of molecules crucial to advances in medicine and the life sc
Chemists at Boston College have designed a new class of catalysts triggered by the charge of a single proton, the team reports in the most recent edition of the journal Nature. The simple organic molecules offer a sustainable and highly efficient platform for chemical reactions that produce sets of molecules crucial to advances in medicine and the life sc
Chemistry
Source: Boston College
Posted on: Thursday, Feb 14, 2013, 2:15pm
Rating: | Views: 1307 | Comments: 0
Source: Boston College
Posted on: Thursday, Feb 14, 2013, 2:15pm
Rating: | Views: 1307 | Comments: 0
Epigenetics shapes fate of brain vs. brawn castes in carpenter ants
The recently published genome sequences of seven well-studied ant species are opening up new vistas for biology and medicine. A detailed look at molecular mechanisms that underlie the complex behavioral differences in two worker castes in the Florida carpenter ant, Camponotus floridanus, has revealed a link to epigenetics. This is the study of how the expression or suppression of pa
The recently published genome sequences of seven well-studied ant species are opening up new vistas for biology and medicine. A detailed look at molecular mechanisms that underlie the complex behavioral differences in two worker castes in the Florida carpenter ant, Camponotus floridanus, has revealed a link to epigenetics. This is the study of how the expression or suppression of pa
Genetics
Source: University of Pennsylvania School of Medicine
Posted on: Thursday, Feb 14, 2013, 1:30pm
Rating: | Views: 1287 | Comments: 0
Source: University of Pennsylvania School of Medicine
Posted on: Thursday, Feb 14, 2013, 1:30pm
Rating: | Views: 1287 | Comments: 0
Emerging cancer drugs may drive bone tumors
Cancer drugs should kill tumors, not encourage their spread. But new evidence suggests that an otherwise promising class of drugs may actually increase the risk of tumors spreading to bone, according to researchers at Washington University School of Medicine in St. Louis.
Cancer drugs should kill tumors, not encourage their spread. But new evidence suggests that an otherwise promising class of drugs may actually increase the risk of tumors spreading to bone, according to researchers at Washington University School of Medicine in St. Louis.
Cancer
Source: Washington University School of Medicine
Posted on: Thursday, Feb 14, 2013, 10:15am
Rating: | Views: 1228 | Comments: 0
Source: Washington University School of Medicine
Posted on: Thursday, Feb 14, 2013, 10:15am
Rating: | Views: 1228 | Comments: 0
Whole genome sequencing better at tracing TB outbreaks than standard test
A new form of genetic testing of the bacteria that causes tuberculosis can provide better information on TB transmission and also trace TB outbreaks more accurately than the current standard test, according to a study from Germany published in this week's PLOS Medicine.
A new form of genetic testing of the bacteria that causes tuberculosis can provide better information on TB transmission and also trace TB outbreaks more accurately than the current standard test, according to a study from Germany published in this week's PLOS Medicine.
Epidemiology
Source: Public Library of Science
Posted on: Wednesday, Feb 13, 2013, 1:30pm
Rating: | Views: 1809 | Comments: 0
Source: Public Library of Science
Posted on: Wednesday, Feb 13, 2013, 1:30pm
Rating: | Views: 1809 | Comments: 0
Molecular master switch for pancreatic cancer identified, potential predictor of treatment outcome
A recently described master regulator protein may explain the development of aberrant cell growth in the pancreas spurred by inflammation A team from the Perelman School of Medicine at the University of Pennsylvania profiled gene expression of mouse pancreatic ductal and duct-like cells from different states - embryonic development, acute pancreatitis and K-ras mutation-driven
A recently described master regulator protein may explain the development of aberrant cell growth in the pancreas spurred by inflammation A team from the Perelman School of Medicine at the University of Pennsylvania profiled gene expression of mouse pancreatic ductal and duct-like cells from different states - embryonic development, acute pancreatitis and K-ras mutation-driven
Molecular Biology
Source: University of Pennsylvania School of Medicine
Posted on: Wednesday, Feb 13, 2013, 12:15pm
Rating: | Views: 9310 | Comments: 1
Source: University of Pennsylvania School of Medicine
Posted on: Wednesday, Feb 13, 2013, 12:15pm
Rating: | Views: 9310 | Comments: 1
Tumor blood vessels prevent the spread of cancer cells
A lack of the protein endoglin in the blood vessels of tumour-bearing mice enables the spread of daughter tumours, according to researchers at Karolinska Institutet and Lund University in Sweden in a study published in the scientific periodical The Journal of Experimental Medicine. Given that the tumour vasculature constitutes an important barrier to the spread of cancer cells, the team sug
A lack of the protein endoglin in the blood vessels of tumour-bearing mice enables the spread of daughter tumours, according to researchers at Karolinska Institutet and Lund University in Sweden in a study published in the scientific periodical The Journal of Experimental Medicine. Given that the tumour vasculature constitutes an important barrier to the spread of cancer cells, the team sug
Cancer
Source: Karolinska Institutet
Posted on: Tuesday, Feb 12, 2013, 10:15am
Rating: | Views: 1112 | Comments: 0
Source: Karolinska Institutet
Posted on: Tuesday, Feb 12, 2013, 10:15am
Rating: | Views: 1112 | Comments: 0
Evaluating evolutionary rates could shed light into functions of uncharacterized genes
Genes that have roles in the same biological pathways change their rate of evolution in parallel, a finding that could be used to discover their functions, said a researcher at the University of Pittsburgh School of Medicine in the February issue of GENETICS.
Genes that have roles in the same biological pathways change their rate of evolution in parallel, a finding that could be used to discover their functions, said a researcher at the University of Pittsburgh School of Medicine in the February issue of GENETICS.
Evolution
Source: University of Pittsburgh Schools of the Health Sciences
Posted on: Monday, Feb 11, 2013, 10:00am
Rating: | Views: 1248 | Comments: 0
Source: University of Pittsburgh Schools of the Health Sciences
Posted on: Monday, Feb 11, 2013, 10:00am
Rating: | Views: 1248 | Comments: 0
Immune systems of healthy adults 'remember' germs to which they've never been exposed
It's established dogma that the immune system develops a "memory" of a microbial pathogen, with a correspondingly enhanced readiness to combat that microbe, only upon exposure to it — or to its components though a vaccine. But a discovery by Stanford University School of Medicine researchers casts doubt on that dogma.
It's established dogma that the immune system develops a "memory" of a microbial pathogen, with a correspondingly enhanced readiness to combat that microbe, only upon exposure to it — or to its components though a vaccine. But a discovery by Stanford University School of Medicine researchers casts doubt on that dogma.
Immunology
Source: Stanford University Medical Center
Posted on: Friday, Feb 08, 2013, 11:45am
Rating: | Views: 1493 | Comments: 0
Source: Stanford University Medical Center
Posted on: Friday, Feb 08, 2013, 11:45am
Rating: | Views: 1493 | Comments: 0
Obesity in dads may be associated with offspring's increased risk of disease
A father's obesity is one factor that may influence his children's health and potentially raise their risk for diseases like cancer, according to new research from Duke Medicine.
A father's obesity is one factor that may influence his children's health and potentially raise their risk for diseases like cancer, according to new research from Duke Medicine.
Genetics
Source: Duke University Medical Center
Posted on: Wednesday, Feb 06, 2013, 4:15pm
Rating: | Views: 2476 | Comments: 0
Source: Duke University Medical Center
Posted on: Wednesday, Feb 06, 2013, 4:15pm
Rating: | Views: 2476 | Comments: 0
Study finds potential to match tumors with known cancer drugs
When it comes to gene sequencing and personalized medicine for cancer, spotting an aberrant kinase is a home run. The proteins are relatively easy to target with drugs and plenty of kinase inhibitors already exist.
When it comes to gene sequencing and personalized medicine for cancer, spotting an aberrant kinase is a home run. The proteins are relatively easy to target with drugs and plenty of kinase inhibitors already exist.
Cancer
Source: University of Michigan Health System
Posted on: Wednesday, Feb 06, 2013, 2:30pm
Rating: | Views: 1134 | Comments: 0
Source: University of Michigan Health System
Posted on: Wednesday, Feb 06, 2013, 2:30pm
Rating: | Views: 1134 | Comments: 0
Researchers spot attention deficits in babies who later develop autism
Researchers at Yale School of Medicine are able to detect deficits in social attention in infants as young as six months of age who later develop Autism Spectrum Disorders (ASD). Published in the current issue of Biological Psychiatry, the results showed that these infants paid less attention to people and their activities than typically developing babies.
Researchers at Yale School of Medicine are able to detect deficits in social attention in infants as young as six months of age who later develop Autism Spectrum Disorders (ASD). Published in the current issue of Biological Psychiatry, the results showed that these infants paid less attention to people and their activities than typically developing babies.
Psychology
Source: Yale University
Posted on: Wednesday, Feb 06, 2013, 10:45am
Rating: | Views: 1465 | Comments: 0
Source: Yale University
Posted on: Wednesday, Feb 06, 2013, 10:45am
Rating: | Views: 1465 | Comments: 0
Wearable cameras provide new insight into lifestyle behaviors and health
Understanding the relationships between lifestyle behaviors and health outcomes can be enhanced by the use of wearable cameras, concludes a collection of studies in a special theme issue of the American Journal of Preventive Medicine. Three studies report on the latest preventive medicine research using Microsoft's wearable camera, the SenseCam.
Understanding the relationships between lifestyle behaviors and health outcomes can be enhanced by the use of wearable cameras, concludes a collection of studies in a special theme issue of the American Journal of Preventive Medicine. Three studies report on the latest preventive medicine research using Microsoft's wearable camera, the SenseCam.
Health
Source: Elsevier Health Sciences
Posted on: Wednesday, Feb 06, 2013, 8:15am
Rating: | Views: 1143 | Comments: 0
Source: Elsevier Health Sciences
Posted on: Wednesday, Feb 06, 2013, 8:15am
Rating: | Views: 1143 | Comments: 0
Growth factor aids stem cell regeneration after radiation damage
Epidermal growth factor has been found to speed the recovery of blood-making stem cells after exposure to radiation, according to Duke Medicine researchers. The finding could open new options for treating cancer patients and victims of dirty bombs or nuclear disasters.
Epidermal growth factor has been found to speed the recovery of blood-making stem cells after exposure to radiation, according to Duke Medicine researchers. The finding could open new options for treating cancer patients and victims of dirty bombs or nuclear disasters.
Molecular Biology
Source: Duke University Medical Center
Posted on: Monday, Feb 04, 2013, 11:45am
Rating: | Views: 1365 | Comments: 0
Source: Duke University Medical Center
Posted on: Monday, Feb 04, 2013, 11:45am
Rating: | Views: 1365 | Comments: 0
Personalized medicine eliminates need for drug in 2 children
Using genome-wide analysis, investigators at the Sainte-Justine University Hospital Research Center and the University of Montreal have potentially eliminated a lifetime drug prescription that two children with a previously unknown type of adrenal insufficiency had been receiving for 14 years.
Using genome-wide analysis, investigators at the Sainte-Justine University Hospital Research Center and the University of Montreal have potentially eliminated a lifetime drug prescription that two children with a previously unknown type of adrenal insufficiency had been receiving for 14 years.
Genetics
Source: University of Montreal
Posted on: Friday, Feb 01, 2013, 12:45pm
Rating: | Views: 1286 | Comments: 0
Source: University of Montreal
Posted on: Friday, Feb 01, 2013, 12:45pm
Rating: | Views: 1286 | Comments: 0
Antibiotics cut death rate for malnourished children
Severely malnourished children are far more likely to recover and survive when given antibiotics along with a therapeutic peanut-based food than children who are simply treated with the therapeutic food alone, researchers at Washington University School of Medicine in St. Louis have found.
Severely malnourished children are far more likely to recover and survive when given antibiotics along with a therapeutic peanut-based food than children who are simply treated with the therapeutic food alone, researchers at Washington University School of Medicine in St. Louis have found.
Health
Source: Washington University School of Medicine
Posted on: Thursday, Jan 31, 2013, 2:00pm
Rating: | Views: 1172 | Comments: 0
Source: Washington University School of Medicine
Posted on: Thursday, Jan 31, 2013, 2:00pm
Rating: | Views: 1172 | Comments: 0
Study highlights attitudes toward HPV vaccination for boys
A new Boston University School of Medicine (BUSM) study has found that low-income and minority parents/guardians were receptive toward vaccinating boys against Human Papilloma Virus (HPV). However, racial/ethnic differences emerged in attitudes regarding school-entry mandates. The findings appear online in the journal Clinical Pediatrics.
A new Boston University School of Medicine (BUSM) study has found that low-income and minority parents/guardians were receptive toward vaccinating boys against Human Papilloma Virus (HPV). However, racial/ethnic differences emerged in attitudes regarding school-entry mandates. The findings appear online in the journal Clinical Pediatrics.
Cancer
Source: Boston University Medical Center
Posted on: Wednesday, Jan 30, 2013, 12:15pm
Rating: | Views: 1136 | Comments: 0
Source: Boston University Medical Center
Posted on: Wednesday, Jan 30, 2013, 12:15pm
Rating: | Views: 1136 | Comments: 0
Altering eye cells may 1 day restore vision
Doctors may one day treat some forms of blindness by altering the genetic program of the light-sensing cells of the eye, according to scientists at Washington University School of Medicine in St. Louis.
Doctors may one day treat some forms of blindness by altering the genetic program of the light-sensing cells of the eye, according to scientists at Washington University School of Medicine in St. Louis.
Neuroscience
Source: Washington University School of Medicine
Posted on: Tuesday, Jan 29, 2013, 10:15am
Rating: | Views: 1147 | Comments: 0
Source: Washington University School of Medicine
Posted on: Tuesday, Jan 29, 2013, 10:15am
Rating: | Views: 1147 | Comments: 0
Misconceptions about a popular pet treat
A popular dog treat could be adding more calories than pet owners realize, and possibly be contaminated by bacteria, according to a study published this month by researchers at the Cummings School of Veterinary Medicine at Tufts University and the University of Guelph.
A popular dog treat could be adding more calories than pet owners realize, and possibly be contaminated by bacteria, according to a study published this month by researchers at the Cummings School of Veterinary Medicine at Tufts University and the University of Guelph.
Health
Source: Tufts University
Posted on: Tuesday, Jan 29, 2013, 8:45am
Rating: | Views: 1168 | Comments: 0
Source: Tufts University
Posted on: Tuesday, Jan 29, 2013, 8:45am
Rating: | Views: 1168 | Comments: 0
Less invasive treatment is associated with improved survival in early stage breast cancer
Patients with early stage breast cancer who were treated with lumpectomy plus radiation may have a better chance of survival compared with those who underwent mastectomy, according to Duke Medicine research.
Patients with early stage breast cancer who were treated with lumpectomy plus radiation may have a better chance of survival compared with those who underwent mastectomy, according to Duke Medicine research.
Cancer
Source: Duke University Medical Center
Posted on: Tuesday, Jan 29, 2013, 8:00am
Rating: | Views: 1090 | Comments: 0
Source: Duke University Medical Center
Posted on: Tuesday, Jan 29, 2013, 8:00am
Rating: | Views: 1090 | Comments: 0
Study shows potential of differentiated iPS cells in cell therapy without immune rejection
A new study from Boston University School of Medicine (BUSM) shows that tissues derived from induced pluripotent stem (iPS) cells in an experimental model were not rejected when transplanted back into genetically identical recipients. The study, published online in Cell Stem Cell, demonstrates the potential of utilizing iPS cells to develop cell types that could offer treatment f
A new study from Boston University School of Medicine (BUSM) shows that tissues derived from induced pluripotent stem (iPS) cells in an experimental model were not rejected when transplanted back into genetically identical recipients. The study, published online in Cell Stem Cell, demonstrates the potential of utilizing iPS cells to develop cell types that could offer treatment f
Stem cells
Source: Boston University Medical Center
Posted on: Monday, Jan 28, 2013, 11:15am
Rating: | Views: 1299 | Comments: 0
Source: Boston University Medical Center
Posted on: Monday, Jan 28, 2013, 11:15am
Rating: | Views: 1299 | Comments: 0
Tumor cells engineer acidity to drive cell invasion
Researchers at Moffitt Cancer Center and colleagues at Wayne State University School of Medicine investigated the acidity in solid tumors to determine if pH levels play a role in cancer cell invasion in surrounding tissues. They found that an acidic microenvironment can drive cancer cells to spread and propose that neutralizing pH would inhibit further invasion, providing a therapeutic opportunity
Researchers at Moffitt Cancer Center and colleagues at Wayne State University School of Medicine investigated the acidity in solid tumors to determine if pH levels play a role in cancer cell invasion in surrounding tissues. They found that an acidic microenvironment can drive cancer cells to spread and propose that neutralizing pH would inhibit further invasion, providing a therapeutic opportunity
Cancer
Source: H. Lee Moffitt Cancer Center & Research Institute
Posted on: Monday, Jan 28, 2013, 8:15am
Rating: | Views: 1203 | Comments: 0
Source: H. Lee Moffitt Cancer Center & Research Institute
Posted on: Monday, Jan 28, 2013, 8:15am
Rating: | Views: 1203 | Comments: 0
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