Diabetes and cancer: A shared biological basis Contrary to what you might think, cancer and diabetes appear to have some biology in common. According to a report in the September 30th issue of the Cell Press journal, Cell, a pathway that initially drew attention for its role in embryonic stem cells and cancer also influences the odds that mice develop or resist diabetes.
Correcting sickle cell disease with stem cells Using a patient's own stem cells, researchers at Johns Hopkins have corrected the genetic alteration that causes sickle cell disease (SCD), a painful, disabling inherited blood disorder that affects mostly African-Americans. The corrected stem cells were coaxed into immature red blood cells in a test tube that then turned on a normal version of the gene.
Agriculture Source: Johns Hopkins Medical Institutions
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Thursday, Sep 29, 2011, 11:15am Rating: | Views: 1177 | Comments: 0
Scientists identify new stem cell activity in human brain Researchers at Barrow Neurological Institute at St. Joseph's Hospital and Medical Center have identified a new pathway of stem cell activity in the brain that represents potential targets of brain injuries affecting newborns. The recent study, which raises new questions of how the brain evolves, is published in the current issue of Nature, one of the world's most cited scientific journals.
Stem cells Source: St. Joseph's Hospital and Medical Center
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Thursday, Sep 29, 2011, 8:15am Rating: | Views: 1112 | Comments: 0
U.K. Approves Europe's First Embryonic Stem Cell Clinical Trial A U.S.-based company has received permission to start Europe's first clinical trial involving human embryonic stem (hES) cells. Advanced Cell Technology (ACT), based in Marlborough, Massachusetts, received approval today from the U.K. Medicines and Healthcare products Regulatory Agency (MHRA) to begin a trial that will treat 12 patients with Stargardt's macular dystrophy.
Bioengineers reprogram muscles to combat degeneration Researchers at the University of California, Berkeley, have turned back the clock on mature muscle tissue, coaxing it back to an earlier stem cell stage to form new muscle. Moreover, they showed in mice that the newly reprogrammed muscle stem cells could be used to help repair damaged tissue.
Molecular Biology Source: University of California - Berkeley
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Thursday, Sep 22, 2011, 1:30pm Rating: | Views: 1346 | Comments: 0
Stem Cell Lawsuit Back Again As expected, the plaintiffs in a law suit claiming that federally funded research on human embryonic stem cells (hESC) is illegal have appealed a ruling that dealt them a defeat earlier this summer.
New type of spinal cord stem cell discovered A group led by a University of British Columbia and Vancouver Coastal Health scientist has discovered a type of spinal cord cell that could function as a stem cell, with the ability to regenerate portions of the central nervous system in people with spinal cord injuries, multiple sclerosis or amyotrophic lateral sclerosis (Lou Gehrig's disease).
Stem cells Source: University of British Columbia
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Thursday, Sep 15, 2011, 6:22pm Rating: | Views: 1084 | Comments: 0
Stem cells Source: Allen Institute for Brain Science
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Thursday, Sep 15, 2011, 11:45am Rating: | Views: 1334 | Comments: 0
Shaping up: Controlling a stem cell's form can determine its fate "Form follows function!" was the credo of early 20th century architects making design choices based on the intended use of the structure. Cell biologists may be turning that on its head. New research reinforces the idea that stem cells can be induced to develop into specific types of cells solely by controlling their shape.
Stem cells Source: National Institute of Standards and Technology (NIST)
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Wednesday, Sep 14, 2011, 8:38am Rating: | Views: 1091 | Comments: 0
Neurosurgeons use adult stem cells to grow neck vertebrae Neurosurgery researchers at UC Davis Health System have used a new, leading-edge stem cell therapy to promote the growth of bone tissue following the removal of cervical discs -- the cushions between the bones in the neck -- to relieve chronic, debilitating pain.
Stem cells Source: University of California - Davis Health System
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Wednesday, Sep 07, 2011, 12:45pm Rating: | Views: 1181 | Comments: 0
Scientists find stem cells that tell hair it's time to grow Yale researchers have discovered the source of signals that trigger hair growth, an insight that may lead to new treatments for baldness.
The researchers identified stem cells within the skin's fatty layer and showed that molecular signals from these cells were necessary to spur hair growth in mice, according to research published in the Sept. 2 issue of the journal Cell.
"If we ca
Stem cells Source: Yale University
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Thursday, Sep 01, 2011, 4:45pm Rating: | Views: 1310 | Comments: 0
New research validates clinical importance of leukemia stem cells Scientists have long debated if all cells within a tumour are equal or whether some cancer cells are more potent - a question that has been highly investigated in experimental models in the last decade. New research shows that acute myeloid leukemia (AML) contains rare cells with stem cell properties, called leukemia stem cells (LSC), that are better at predicting clinical outcome
Cancer Source: University Health Network
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Monday, Aug 29, 2011, 11:15am Rating: | Views: 1180 | Comments: 0
An RNA Switch for Stem Cells A new study reveals the influence of large RNA molecules in controlling stem cells.
RNA molecules have long been known for their role in translating genes to proteins inside a cell, but more recently, scientists have found large numbers of RNA molecules that don't code for proteins but seem to have other cellular roles. Most research in mammals has focused on tiny RNA molecules called microRNAs, but a new study, published this week in Nature, describes the far-reaching effects of much larger and relatively unstudied RNA molecules called lincRNAs (short for large intergenic noncoding RNAs). The study identifies lincRNAs that play a role in the function of embryonic stem cells, and suggests trying to use lincRNAs to manipulate these cells to spawn other cell types.
Molecular Biology Source: Technology Review
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Monday, Aug 29, 2011, 7:53am Rating: | Views: 1088 | Comments: 0
Molecular chaperones traffic signaling proteins between cells in plant stem-cell maintenance pathway Like all living things, plants depend for their growth and sustenance on elaborate signaling networks to maintain stem cells, cells that have an almost magical regenerative capacity. The signals sent through these networks convey an incredible diversity of instructions, which make it possible for plants to follow genetic and cellular programs regulating growth, shape, and
Molecular Biology Source: Cold Spring Harbor Laboratory
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Friday, Aug 26, 2011, 8:15am Rating: | Views: 1436 | Comments: 0
'Open wide' for new stem cell potential While highly potent embryonic stem cells are often the subject of ethical and safety controversy, adult-derived stem cells have other problems. As we age, our stem cells are less pliant and less able to transform into the stem cells that science needs to find breakthrough treatments for disease.
Stem cells Source: American Friends of Tel Aviv University
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Tuesday, Aug 23, 2011, 12:30pm Rating: | Views: 1109 | Comments: 0
Cancer stem cells made, not born In cancer, tumors aren't uniform: they are more like complex societies, each with a unique balance of cancer cell types playing different roles. Understanding this "social structure" of tumors is critical for treatment decisions in the clinic because different cell types may be sensitive to different drugs.
Cancer Source: Broad Institute of MIT and Harvard
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Friday, Aug 19, 2011, 5:45pm Rating: | Views: 1333 | Comments: 0
Cells derived from pluripotent stem cells are developmentally immature Stem cell researchers at UCLA have discovered that three types of cells derived from human embryonic stem cells and induced pluripotent stem cells are similar to each other, but are much more developmentally immature than previously thought when compared to those same cell types taken directly from human tissue.
Stem cells Source: University of California - Los Angeles Health Sciences
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Thursday, Aug 18, 2011, 4:30pm Rating: | Views: 1088 | Comments: 0
Stem cells central to pathogenesis of mature lymphoid tumors New research suggests that blood stem cells can be involved in the generation of leukemia, even when the leukemia is caused by the abnormal proliferation of mature cells. The study, published by Cell Press in the August 16th issue of the journal Cancer Cell, may guide future strategies aimed at identifying therapeutic targets for chronic lymphocytic leukemia (CLL).
Cancer Source: Cell Press
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Wednesday, Aug 17, 2011, 12:30pm Rating: | Views: 1122 | Comments: 0
Discovery may eliminate potentially lethal side effect of stem cell therapy Like fine chefs, scientists are seemingly approaching a day when they will be able to make nearly any type of tissue from human embryonic stem cells. You need nerves or pancreas, bone or skin? With the right combination of growth factors, skill and patience, a laboratory tissue culture dish promises to yield therapeutic wonders.
Stem cells Source: Stanford University Medical Center
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Monday, Aug 15, 2011, 10:30am Rating: | Views: 1173 | Comments: 0
Stem cells Source: University of California - Los Angeles Health Sciences
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Tuesday, Aug 09, 2011, 1:15pm Rating: | Views: 1302 | Comments: 0
A patient's own skin cells may one day treat multiple diseases The possibility of developing stem cells from a patient's own skin and using them to treat conditions as diverse as Parkinson's disease, Alzheimer's disease and cancer has generated tremendous excitement in the stem cell research community in recent years.
Stem cells Source: University of California - Davis Health System
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Friday, Aug 05, 2011, 8:15am Rating: | Views: 1286 | Comments: 0
Stem cells Source: UT Southwestern Medical Center
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Thursday, Aug 04, 2011, 2:15pm Rating: | Views: 1115 | Comments: 0
Making sperm from stem cells in a dish Researchers have found a way to turn mouse embryonic stem cells into sperm. This finding, reported in the journal Cell in a special online release on August 4th, opens up new avenues for infertility research and treatment. A Kyoto University team has coaxed mouse embryonic stem cells into sperm precursors, called primordial germ cells (PGCs), and shown that these cells can give rise to he
Stem cells Source: Cell Press
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Thursday, Aug 04, 2011, 1:30pm Rating: | Views: 1130 | Comments: 0
Mitochondrial genome mutates when reprogrammed Induced pluripotent stem cells (iPS cells) are truly talented multi-taskers. They can reproduce almost all cell types and thus offer great hope in the fight against diseases like Alzheimer's and Parkinson's. However, it would appear that their use is not entirely without risk: during the reprogramming of body cells into iPS cells, disease-causing mutations can creep into the genetic material.
Cancer Source: University of Michigan Health System
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Monday, Jul 18, 2011, 4:00pm Rating: | Views: 1232 | Comments: 0
Precision gene targeting in stem cells corrects disease-causing mutations Using two distinct methods, Whitehead Institute researchers have successfully and consistently manipulated targeted genes in both human embryonic stem (ES) cells and induced pluripotent stem (iPS) cells (adult cells that have been reprogrammed to an embryonic stem cell-like state).
Molecular Biology Source: Whitehead Institute for Biomedical Research
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Friday, Jul 15, 2011, 2:45pm Rating: | Views: 1281 | Comments: 1
New technique boosts efficiency of blood cell production from human stem cells Scientists at the Salk Institute for Biological Studies have developed an improved technique for generating large numbers of blood cells from a patient's own cells. The new technique will be immediately useful in further stem cell studies, and when perfected, could be used in stem cell therapies for a wide variety of conditions including cancers and immune ailments.
Stem cells Source: Salk Institute
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Friday, Jul 15, 2011, 2:30pm Rating: | Views: 1108 | Comments: 0
Efficient process using microrna converts human skin cells into neurons The addition of two particular gene snippets to a skin cell's usual genetic material is enough to turn that cell into a fully functional neuron, report researchers from the Stanford University School of Medicine. The finding, to be published online July 13 in Nature, is one of just a few recent reports of ways to create human neurons in a lab dish.
Stem cells Source: Stanford University Medical Center
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Thursday, Jul 14, 2011, 10:45am Rating: | Views: 1114 | Comments: 0