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Measles vaccine given with a microneedle patch could boost immunization programs
Measles vaccine given with painless and easy-to-administer microneedle patches can immunize against measles at least as well as vaccine given with conventional hypodermic needles, according to research done by the Georgia Institute of Technology and the Centers for Disease Control and Prevention (CDC).
Immunology
Source: Georgia Institute of Technology Research News
Posted on: Wednesday, Nov 28, 2012, 2:30pm
Rating: | Views: 8849 | Comments: 0
Man's best friend: Common canine virus may lead to new vaccines for deadly human diseases
Researchers at the University of Georgia have discovered that a virus commonly found in dogs may serve as the foundation for human vaccine development.
Immunology
Source: University of Georgia
Posted on: Wednesday, Nov 28, 2012, 1:15pm
Rating: | Views: 14079 | Comments: 0
RSV study shows potential for vaccine strategies to protect babies
Research by the University of Warwick indicates that vaccinating families could protect young babies against a common winter virus which can be fatal for infants under six months. Respiratory syncytial virus (RSV) typically leads to mild, cold-like symptoms in adults and older children but can be more serious and even fatal in infants under the age of six months as it can lead to bronchiolitis
Immunology
Source: University of Warwick
Posted on: Monday, Nov 19, 2012, 11:15am
Rating: | Views: 1217 | Comments: 0
Appetite suppressant for scavenger cells
When infected with influenza, the body becomes an easy target for bacteria. The flu virus alters the host's immune system and compromises its capacity to effectively fight off bacterial infections. Now, a team of immunologists at the Helmholtz Centre for Infection Research (HZI) and cooperation partners has discovered that an immune system molecule called TLR7 is partly to blame. The molecule reco
Immunology
Source: Helmholtz Centre for Infection Research
Posted on: Monday, Nov 19, 2012, 10:15am
Rating: | Views: 1416 | Comments: 0
How infection can trigger autoimmune disease
Australian scientists have confirmed a 'weak link' in the immune system – identifying the exact conditions under which an infection can trigger an autoantibody response, a process not clearly understood until now.
Immunology
Source: Research Australia
Posted on: Wednesday, Nov 14, 2012, 8:30am
Rating: | Views: 1293 | Comments: 0
New drug target found for cystic fibrosis lung disease
Vancouver researchers have discovered the cellular pathway that causes lung-damaging inflammation in cystic fibrosis (CF), and that reducing the pathway's activity also decreases inflammation. The finding offers a potential new drug target for treating CF lung disease, which is a major cause of illness and death for people with CF.
Immunology
Source: Child & Family Research Institute
Posted on: Thursday, Nov 08, 2012, 11:00am
Rating: | Views: 1270 | Comments: 0
Team finds a new way to inhibit blood clotting and inflammation
Scientists have identified a group of small molecules that interfere with the activity of a compound that initiates multiple steps in blood clotting, including those that lead to the obstruction of veins or arteries, a condition called thrombosis. Blocking the activity of this compound, polyphosphate, could treat thrombosis with fewer bleeding side effects than the drugs that are
Immunology
Source: University of Illinois at Urbana-Champaign
Posted on: Wednesday, Nov 07, 2012, 11:00am
Rating: | Views: 1284 | Comments: 0
New DNA vaccine technology poised to deliver safe and cost-effective disease protection
New and increasingly sophisticated vaccines are taking aim at a broad range of disease-causing pathogens, targeting them with greater effectiveness at lower cost and with improved measures to ensure safety.
Immunology
Source: Arizona State University
Posted on: Tuesday, Nov 06, 2012, 1:15pm
Rating: | Views: 1846 | Comments: 0
Mice with 'humanized' livers improve early drug testing
Stanford University School of Medicine scientists have used bioengineered mice with livers composed largely of human cells to characterize a drug about to enter early-stage clinical development for combating hepatitis C.
Immunology
Source: Stanford University Medical Center
Posted on: Thursday, Nov 01, 2012, 2:00pm
Rating: | Views: 1410 | Comments: 0
How and why herpes viruses reactivate to cause disease
The mere mention of the word "herpes" usually conjures negative images and stereotypes, but most people have been infected with some form of the virus. For most, a sore appears, heals and is forgotten, although the virus remains latent just waiting for the right circumstances to come back. Now, the mystery behind what triggers the virus to become active again is closer to being solved thanks to ne
Immunology
Source: Federation of American Societies for Experimental Biology
Posted on: Thursday, Nov 01, 2012, 11:15am
Rating: | Views: 1207 | Comments: 0
Recent findings may help to fight melanoma's resistance to chemotherapy
Blocking the action of a particular protein in our skin could improve the treatment of skin cancers, according to a study published in Oncogene yesterday by Philippe Roux, a researcher at the University of Montreal's Institute for Research in Immunology and Cancer (IRIC).
Cancer
Source: University of Montreal
Posted on: Thursday, Nov 01, 2012, 8:15am
Rating: | Views: 1225 | Comments: 0
Mechanism found for destruction of key allergy-inducing complexes
Researchers have learned how a man-made molecule destroys complexes that induce allergic responses — a discovery that could lead to the development of highly potent, rapidly acting interventions for a host of acute allergic reactions.
Immunology
Source: Stanford University Medical Center
Posted on: Monday, Oct 29, 2012, 11:15am
Rating: | Views: 1705 | Comments: 0
An animal model of typhoid fever could lead to better vaccines
The first mouse model of the common bacterial disease typhoid fever is reported in a study published by Cell Press October 25 in the journal Cell. Because the animals show human-like symptoms and respond positively to immunization, they could be used to develop more effective vaccines against the deadly pathogen.
Immunology
Source: Cell Press
Posted on: Friday, Oct 26, 2012, 1:00pm
Rating: | Views: 1493 | Comments: 0
Stem cell bodyguards
Hiding deep inside the bone marrow are special cells. They wait patiently for the hour of need, at which point these blood forming stem cells can proliferate and differentiate into billions of mature blood immune cells to help the body cope with infection, for example, or extra red blood cells for low oxygen levels at high altitudes. Even in emergencies, however, the body keeps to a long-term plan
Immunology
Source: Weizmann Institute of Science
Posted on: Tuesday, Oct 23, 2012, 8:30am
Rating: | Views: 1184 | Comments: 0
Mosquitoes: No antibodies, no problem
Researchers at the Johns Hopkins Bloomberg School of Public Health have determined a new mechanism by which the mosquitoes' immune system can respond with specificity to infections with various pathogens, including the parasite that causes malaria in humans, using one single gene. Unlike humans and other animals, insects do not make antibodies to target specific infections. According to the Johns
Immunology
Source: Johns Hopkins University Bloomberg School of Public Health
Posted on: Friday, Oct 19, 2012, 12:00pm
Rating: | Views: 1291 | Comments: 0
Rare cells regulate immune responses; May offer novel treatment for autoimmune diseases
Reproducing a rare type of B cell in the laboratory and infusing it back into the body may provide an effective treatment for severe autoimmune diseases such as multiple sclerosis or rheumatoid arthritis, according to researchers at Duke University Medical Center.
Immunology
Source: Duke University Medical Center
Posted on: Monday, Oct 15, 2012, 11:45am
Rating: | Views: 1213 | Comments: 0
Researchers uncover molecular basis of infection of tick-transmitted disease
Virginia Commonwealth University School of Medicine researchers have identified the "keys" and "doors" of a bacterium responsible for a series of tick-transmitted diseases. These findings may point researchers toward the development of a single vaccine that protects against members of an entire family of bacteria that cause disease in humans, domestic animals and li
Immunology
Source: Virginia Commonwealth University
Posted on: Monday, Oct 15, 2012, 10:45am
Rating: | Views: 1192 | Comments: 0
Research gives new insight into celiac disease
For the first time, scientists have visualised an interaction between gluten and T-cells of the immune system, providing insight into how coeliac disease, which affects approximately 1 in 133 people, is triggered.
Immunology
Source: Monash University
Posted on: Friday, Oct 12, 2012, 1:15pm
Rating: | Views: 1256 | Comments: 0
Stopping the itch -- new clues into how to treat eczema
More than 15% of children suffer with eczema, or atopic dermatitis, an inflammatory skin disease that in some cases can be debilitating and disfiguring. Researchers reporting in the October issue of Immunity have discovered a potential new target for the condition, demonstrating that by blocking it, they can lessen the disease in mice.
Immunology
Source: Cell Press
Posted on: Friday, Oct 12, 2012, 12:15pm
Rating: | Views: 1690 | Comments: 0
Recovering 'bodyguard' cells in pancreas may restore insulin production in diabetics
The key to restoring production of insulin in type I diabetic patients, previously known as juvenile diabetes, may be in recovering the population of protective cells known T regulatory cells in the lymph nodes at the "gates" of the pancreas, a new preclinical study published online October 8 in Cellular & Molecular Immunology by researchers in the Department of Bioscience Tech
Immunology
Source: Thomas Jefferson University
Posted on: Tuesday, Oct 09, 2012, 1:45pm
Rating: | Views: 1345 | Comments: 0
Study suggests immune system can boost regeneration of peripheral nerves
Modulating immune response to injury could accelerate the regeneration of severed peripheral nerves, a new study in an animal model has found. By altering activity of the macrophage cells that respond to injuries, researchers dramatically increased the rate at which nerve processes regrew.
Immunology
Source: Georgia Institute of Technology Research News
Posted on: Wednesday, Oct 03, 2012, 11:00am
Rating: | Views: 1169 | Comments: 0
Researchers halt autoimmune disease myasthenia gravis in mice
Working with mice, Johns Hopkins researchers say they have developed a gene-based therapy to stop the rodent equivalent of the autoimmune disease myasthenia gravis by specifically targeting the destructive immune response the disorder triggers in the body.
Immunology
Source: Johns Hopkins Medicine
Posted on: Tuesday, Oct 02, 2012, 11:15am
Rating: | Views: 1933 | Comments: 0
Penn immunologists find a molecule that puts the brakes on inflammation
We couldn't live without our immune systems, always tuned to detect and eradicate invading pathogens and particles. But sometimes the immune response goes overboard, triggering autoimmune diseases like lupus, asthma or inflammatory bowel disease.
Immunology
Source: University of Pennsylvania
Posted on: Monday, Oct 01, 2012, 12:00pm
Rating: | Views: 1258 | Comments: 0
Researchers determine how inflammatory cells function, setting stage for future remedies
A research team led by investigators at New York University and NYU School of Medicine has determined how cells that cause inflammatory ailments, such as Crohn's disease, multiple sclerosis, and arthritis, differentiate from stem cells and ultimately affect the clinical outcome of these diseases.
Immunology
Source: New York University
Posted on: Thursday, Sep 27, 2012, 2:00pm
Rating: | Views: 1262 | Comments: 0
Pregnancy generates maternal immune-suppressive cells that protect the fetus
A new study published online in the journal Nature suggests it might be possible to develop vaccines to prevent premature birth and other pregnancy complications. If so, such vaccines would be the first intended to stimulate the subset of regulatory CD4 T cells that suppress the immune response.
Immunology
Source: Cincinnati Children's Hospital Medical Center
Posted on: Thursday, Sep 27, 2012, 12:30pm
Rating: | Views: 1467 | Comments: 0
Discovery may shed light on why some HIV-positive patients have more virus
Biologists at UC San Diego have unraveled the anti-viral mechanism of a human gene that may explain why some people infected with HIV have much higher amounts of virus in their bloodstreams than others.
Immunology
Source: University of California - San Diego
Posted on: Tuesday, Sep 25, 2012, 8:15am
Rating: | Views: 1143 | Comments: 0
In heterosexuals, transmitted HIV strains often resemble original infecting virus
A new study has found that even though HIV diversifies widely within infected individuals over time, the virus strains that ultimately are passed on through heterosexual transmission often resemble the strain of virus that originally infected the transmitting partner. Learning the characteristics of these preferentially transmitted HIV strains may help advance HIV prevention effor
Immunology
Source: NIH/National Institute of Allergy and Infectious Diseases
Posted on: Friday, Sep 21, 2012, 10:30am
Rating: | Views: 1261 | Comments: 0
Study finds that natural killer T-cells in fat tissue guard against obesity
Invariant natural killer T-cells (iNKT) are a unique subset of immune cells that are known to influence inflammatory responses. Now, a scientific team led by researchers at Beth Israel Deaconess Medical Center (BIDMC) has found that iNKT cells play a protective role in guarding against obesity and the metabolic syndrome, a major consequence of obesity.
Immunology
Source: Beth Israel Deaconess Medical Center
Posted on: Friday, Sep 14, 2012, 12:30pm
Rating: | Views: 1570 | Comments: 0
Hayfever vaccine study raises hopes for new allergy treatment as clinical trial is launched
Researchers are developing a new vaccine for hayfever which could be more effective, less invasive for patients and less expensive than vaccines already available to patients within the NHS.
Immunology
Source: King's College London
Posted on: Tuesday, Sep 11, 2012, 11:30am
Rating: | Views: 1918 | Comments: 0
Research helps explain why an AIDS vaccine has been so difficult to develop
For decades, a successful HIV vaccine has been the Holy Grail for researchers around the globe. Yet despite years of research and millions of dollars of investment, that goal has still yet to be achieved. Recent research by Oregon Health & Science University scientists explains a decades-old mystery as to why slightly weakened versions of the monkey AIDS virus were able to prevent
Immunology
Source: Oregon Health & Science University
Posted on: Monday, Sep 10, 2012, 12:00pm
Rating: | Views: 1230 | Comments: 0
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