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Lungs respond to hospital ventilator as if it were an infection 
When hospital patients need assistance breathing and are placed on a mechanical ventilator for days at a time, their lungs react to the pressure generated by the ventilator with an out-of-control immune response that can lead to excessive inflammation, new research suggests.
When hospital patients need assistance breathing and are placed on a mechanical ventilator for days at a time, their lungs react to the pressure generated by the ventilator with an out-of-control immune response that can lead to excessive inflammation, new research suggests.
Immunology
Source: Ohio State University
Posted on: Thursday, Jul 19, 2012, 1:45pm
Rating: | Views: 1346 | Comments: 0
Source: Ohio State University
Posted on: Thursday, Jul 19, 2012, 1:45pm
Rating: | Views: 1346 | Comments: 0
Mouse with human immune system may revolutionize HIV vaccine research
One of the challenges to HIV vaccine development has been the lack of an animal model that accurately reflects the human immune response to the virus and how the virus evolves to evade that response. In the July 18 issue of Science Translational Medicine, researchers from the Ragon Institute of Massachusetts General Hospital (MGH), MIT and Harvard report that a model created by transplantin
One of the challenges to HIV vaccine development has been the lack of an animal model that accurately reflects the human immune response to the virus and how the virus evolves to evade that response. In the July 18 issue of Science Translational Medicine, researchers from the Ragon Institute of Massachusetts General Hospital (MGH), MIT and Harvard report that a model created by transplantin
Immunology
Source: Massachusetts General Hospital
Posted on: Thursday, Jul 19, 2012, 1:15pm
Rating: | Views: 1172 | Comments: 0
Source: Massachusetts General Hospital
Posted on: Thursday, Jul 19, 2012, 1:15pm
Rating: | Views: 1172 | Comments: 0
Widely prescribed MS treatment may not slow progression of disease
Researchers with the UBC Hospital MS Clinic and Brain Research Centre at Vancouver Coastal Health and the University of British Columbia have published important data in the Journal of the American Medical Association (JAMA) about the impact of a common drug therapy on the progression of multiple sclerosis for people with the relapsing‑remitting form of the disease.
Researchers with the UBC Hospital MS Clinic and Brain Research Centre at Vancouver Coastal Health and the University of British Columbia have published important data in the Journal of the American Medical Association (JAMA) about the impact of a common drug therapy on the progression of multiple sclerosis for people with the relapsing‑remitting form of the disease.
Immunology
Source: University of British Columbia
Posted on: Wednesday, Jul 18, 2012, 1:00pm
Rating: | Views: 1193 | Comments: 0
Source: University of British Columbia
Posted on: Wednesday, Jul 18, 2012, 1:00pm
Rating: | Views: 1193 | Comments: 0
Critical cell identified in the fight against E. coli infection
Despite ongoing public health efforts, E. coli outbreaks continue to infiltrate the food supply, annually causing significant sickness and death throughout the world. But the research community is gaining ground. In a major finding, published today in the scientific journal Nature, researchers from the La Jolla Institute for Allergy & Immunology have
Despite ongoing public health efforts, E. coli outbreaks continue to infiltrate the food supply, annually causing significant sickness and death throughout the world. But the research community is gaining ground. In a major finding, published today in the scientific journal Nature, researchers from the La Jolla Institute for Allergy & Immunology have
Microbiology
Source: La Jolla Institute for Allergy and Immunology
Posted on: Monday, Jul 16, 2012, 11:00am
Rating: | Views: 1161 | Comments: 0
Source: La Jolla Institute for Allergy and Immunology
Posted on: Monday, Jul 16, 2012, 11:00am
Rating: | Views: 1161 | Comments: 0
Scientists discover viral protein that prevents the body from fighting HIV
University of Washington researchers have made a discovery that sheds light on why the human body is unable to adequately fight off HIV infection.
University of Washington researchers have made a discovery that sheds light on why the human body is unable to adequately fight off HIV infection.
Immunology
Source: University of Washington
Posted on: Friday, Jul 13, 2012, 8:00am
Rating: | Views: 1199 | Comments: 0
Source: University of Washington
Posted on: Friday, Jul 13, 2012, 8:00am
Rating: | Views: 1199 | Comments: 0
TLR1 protein drives immune response to certain food-borne illness in mice
A naturally occurring protein called TLR1 plays a critical role in protecting the body from illnesses caused by eating undercooked pork or drinking contaminated water, according to new research from the University of Southern California (USC).
A naturally occurring protein called TLR1 plays a critical role in protecting the body from illnesses caused by eating undercooked pork or drinking contaminated water, according to new research from the University of Southern California (USC).
Immunology
Source: University of Southern California - Health Sciences
Posted on: Tuesday, Jul 10, 2012, 11:30am
Rating: | Views: 1180 | Comments: 0
Source: University of Southern California - Health Sciences
Posted on: Tuesday, Jul 10, 2012, 11:30am
Rating: | Views: 1180 | Comments: 0
Keeping the flu away
San Diego State University researchers at the Donald P. Shiley BioScience Center may have found the secret to helping the immune system fight off the flu before it gets you sick.
San Diego State University researchers at the Donald P. Shiley BioScience Center may have found the secret to helping the immune system fight off the flu before it gets you sick.
Immunology
Source: San Diego State University
Posted on: Monday, Jul 09, 2012, 8:30am
Rating: | Views: 1141 | Comments: 0
Source: San Diego State University
Posted on: Monday, Jul 09, 2012, 8:30am
Rating: | Views: 1141 | Comments: 0
Antibodies reverse type 1 diabetes in new immunotherapy study
Scientists at the University of North Carolina School of Medicine have used injections of antibodies to rapidly reverse the onset of Type I diabetes in mice genetically bred to develop the disease. Moreover, just two injections maintained disease remission indefinitely without harming the immune system.
Scientists at the University of North Carolina School of Medicine have used injections of antibodies to rapidly reverse the onset of Type I diabetes in mice genetically bred to develop the disease. Moreover, just two injections maintained disease remission indefinitely without harming the immune system.
Immunology
Source: University of North Carolina Health Care
Posted on: Friday, Jul 06, 2012, 2:00pm
Rating: | Views: 1303 | Comments: 0
Source: University of North Carolina Health Care
Posted on: Friday, Jul 06, 2012, 2:00pm
Rating: | Views: 1303 | Comments: 0
T-cell Vaccines Could Treat Elusive Diseases
A biotech company believes it can create the first effective T-cell vaccines. If it is right, it would redefine infectious medicine.
A biotech company believes it can create the first effective T-cell vaccines. If it is right, it would redefine infectious medicine.
Immunology
Source: Technology Review
Posted on: Tuesday, Jul 03, 2012, 8:24am
Rating: | Views: 1119 | Comments: 0
Source: Technology Review
Posted on: Tuesday, Jul 03, 2012, 8:24am
Rating: | Views: 1119 | Comments: 0
Lymph node roundabout
\An organism's ability to make new antibodies and use them to optimize its own immune defenses is of central importance in the fight against pathogens. In the case of severe infections, the overall relative speed with which an immune response proceeds could mean the difference between life and death.
\An organism's ability to make new antibodies and use them to optimize its own immune defenses is of central importance in the fight against pathogens. In the case of severe infections, the overall relative speed with which an immune response proceeds could mean the difference between life and death.
Immunology
Source: Helmholtz Centre for Infection Research
Posted on: Monday, Jul 02, 2012, 8:00am
Rating: | Views: 1245 | Comments: 0
Source: Helmholtz Centre for Infection Research
Posted on: Monday, Jul 02, 2012, 8:00am
Rating: | Views: 1245 | Comments: 0
Flu immunity is affected by how many viruses actually cause the infection
Not only does the type of flu virus affect a patient's outcome, but a new research report appearing in the Journal of Leukocyte Biology suggests that the number of viruses involved in the initial infection may be important too. Scientists from Canada found that when mice were infected by relatively high concentrations of the flu virus, they not only developed immunity against t
Not only does the type of flu virus affect a patient's outcome, but a new research report appearing in the Journal of Leukocyte Biology suggests that the number of viruses involved in the initial infection may be important too. Scientists from Canada found that when mice were infected by relatively high concentrations of the flu virus, they not only developed immunity against t
Immunology
Source: Federation of American Societies for Experimental Biology
Posted on: Thursday, Jun 28, 2012, 1:45pm
Rating: | Views: 1219 | Comments: 0
Source: Federation of American Societies for Experimental Biology
Posted on: Thursday, Jun 28, 2012, 1:45pm
Rating: | Views: 1219 | Comments: 0
TB treatment paradox: Mouse studies show body's own response helps TB bacteria survive
Inhibiting a key immune response in mice during initial multi-drug treatment for tuberculosis could — paradoxically — shorten treatment time for the highly contagious lung infection according to new research from Johns Hopkins Children's Center and the Center for TB Research.
Inhibiting a key immune response in mice during initial multi-drug treatment for tuberculosis could — paradoxically — shorten treatment time for the highly contagious lung infection according to new research from Johns Hopkins Children's Center and the Center for TB Research.
Immunology
Source: Johns Hopkins Medical Institutions
Posted on: Thursday, Jun 28, 2012, 12:15pm
Rating: | Views: 1201 | Comments: 0
Source: Johns Hopkins Medical Institutions
Posted on: Thursday, Jun 28, 2012, 12:15pm
Rating: | Views: 1201 | Comments: 0
Study reveals flu-fighting role for well-known immune component
University of Georgia scientists have discovered a new flu-fighting role for a well-known component of the immune system. Kimberly Klonowski, assistant professor of cellular biology in the UGA Franklin College of Arts and Sciences, and her colleagues found that administering a cell-signaling protein known as IL-15 to mice infected with influenza reduces their peak viral load by nearl
University of Georgia scientists have discovered a new flu-fighting role for a well-known component of the immune system. Kimberly Klonowski, assistant professor of cellular biology in the UGA Franklin College of Arts and Sciences, and her colleagues found that administering a cell-signaling protein known as IL-15 to mice infected with influenza reduces their peak viral load by nearl
Immunology
Source: University of Georgia
Posted on: Tuesday, Jun 26, 2012, 12:15pm
Rating: | Views: 1103 | Comments: 0
Source: University of Georgia
Posted on: Tuesday, Jun 26, 2012, 12:15pm
Rating: | Views: 1103 | Comments: 0
Researchers reveal crucial immune fighter role of the STING protein
Researchers at Weill Cornell Medical College have unlocked the structure of a key protein that, when sensing certain viruses and bacteria, triggers the body's immediate immune response.
Researchers at Weill Cornell Medical College have unlocked the structure of a key protein that, when sensing certain viruses and bacteria, triggers the body's immediate immune response.
Immunology
Source: New York- Presbyterian Hospital/Weill Cornell Medical Center/Weill Cornell Medical College
Posted on: Tuesday, Jun 19, 2012, 12:00pm
Rating: | Views: 1129 | Comments: 0
Source: New York- Presbyterian Hospital/Weill Cornell Medical Center/Weill Cornell Medical College
Posted on: Tuesday, Jun 19, 2012, 12:00pm
Rating: | Views: 1129 | Comments: 0
Control gene for 'conveyor belt' cells could help improve oral vaccines, treat intestinal disease
Scientists have found a master regulator gene needed for the development of M cells, a mysterious type of intestinal cell involved in initiating immune responses.
Scientists have found a master regulator gene needed for the development of M cells, a mysterious type of intestinal cell involved in initiating immune responses.
Immunology
Source: Emory University
Posted on: Monday, Jun 18, 2012, 11:00am
Rating: | Views: 1153 | Comments: 0
Source: Emory University
Posted on: Monday, Jun 18, 2012, 11:00am
Rating: | Views: 1153 | Comments: 0
Scientists show lack of single protein results in persistent viral infection
Scientists from The Scripps Research Institute have shown a single protein can make the difference between an infection clearing out of the body or persisting for life. The results also show where the defects occur in the immune system without the protein and offer the possibility that targeting this signaling pathway could be beneficial for treatment of persistent
Scientists from The Scripps Research Institute have shown a single protein can make the difference between an infection clearing out of the body or persisting for life. The results also show where the defects occur in the immune system without the protein and offer the possibility that targeting this signaling pathway could be beneficial for treatment of persistent
Immunology
Source: Scripps Research Institute
Posted on: Thursday, Jun 14, 2012, 11:00am
Rating: | Views: 1080 | Comments: 0
Source: Scripps Research Institute
Posted on: Thursday, Jun 14, 2012, 11:00am
Rating: | Views: 1080 | Comments: 0
Timing, duration of biochemical bugle call critical for fighting viruses
Researchers have identified the primary player of the biochemical bugle call that musters the body's defenders against viral infection.
Researchers have identified the primary player of the biochemical bugle call that musters the body's defenders against viral infection.
Immunology
Source: Washington University School of Medicine
Posted on: Thursday, Jun 14, 2012, 10:45am
Rating: | Views: 1288 | Comments: 0
Source: Washington University School of Medicine
Posted on: Thursday, Jun 14, 2012, 10:45am
Rating: | Views: 1288 | Comments: 0
Immune cells in the gut may improve control of HIV growth
The findings of a new study in monkeys may help clarify why some people infected with HIV are better able to control the virus. They also may pinpoint a target for treatment during early HIV infection aimed at increasing the supply of certain immune cells in the gut, which the study shows could be an important factor in limiting HIV growth in cells throughout the body.
The findings of a new study in monkeys may help clarify why some people infected with HIV are better able to control the virus. They also may pinpoint a target for treatment during early HIV infection aimed at increasing the supply of certain immune cells in the gut, which the study shows could be an important factor in limiting HIV growth in cells throughout the body.
Immunology
Source: University of North Carolina Health Care
Posted on: Monday, Jun 11, 2012, 1:00pm
Rating: | Views: 1132 | Comments: 0
Source: University of North Carolina Health Care
Posted on: Monday, Jun 11, 2012, 1:00pm
Rating: | Views: 1132 | Comments: 0
Moffitt Cancer Center researchers develop and test new anti-cancer vaccine
Researchers at Moffitt Cancer Center have developed and tested in mice a synthetic vaccine and found it effective in killing human papillomavirus-derived cancer, a virus linked to cervical cancers among others. The research was published in a recent issue of Cancer Immunology, Immunotherapy.
Researchers at Moffitt Cancer Center have developed and tested in mice a synthetic vaccine and found it effective in killing human papillomavirus-derived cancer, a virus linked to cervical cancers among others. The research was published in a recent issue of Cancer Immunology, Immunotherapy.
Cancer
Source: H. Lee Moffitt Cancer Center & Research Institute
Posted on: Monday, Jun 11, 2012, 8:15am
Rating: | Views: 1184 | Comments: 0
Source: H. Lee Moffitt Cancer Center & Research Institute
Posted on: Monday, Jun 11, 2012, 8:15am
Rating: | Views: 1184 | Comments: 0
Mystery to the origin of long-lived, skin-deep immune cells uncovered
Scientists at A*STAR's Singapore Immunology Network (SIgN) uncovered the origin of a group of skin-deep immune cells that act as the first line of defence against harmful germs and skin infections. SIgN scientists discovered that these sentry cells of the skin, called the Langerhans cells (LCs), originate from two distinct embryonic sites - the early yolk sac and the foetal liver.
Scientists at A*STAR's Singapore Immunology Network (SIgN) uncovered the origin of a group of skin-deep immune cells that act as the first line of defence against harmful germs and skin infections. SIgN scientists discovered that these sentry cells of the skin, called the Langerhans cells (LCs), originate from two distinct embryonic sites - the early yolk sac and the foetal liver.
Immunology
Source: Agency for Science, Technology and Research (A*STAR), Singapore
Posted on: Thursday, Jun 07, 2012, 4:15pm
Rating: | Views: 1120 | Comments: 0
Source: Agency for Science, Technology and Research (A*STAR), Singapore
Posted on: Thursday, Jun 07, 2012, 4:15pm
Rating: | Views: 1120 | Comments: 0
Good bugs gone bad: Gut immune cells keep beneficial microbes in their place
The healthy human intestine is colonized with over 100 trillion beneficial, or commensal, bacteria of many different species. In healthy people, these bacteria are limited to the intestinal tissues and have a number of helpful properties, including aiding in the digestion of food and promoting a healthy immune system.
The healthy human intestine is colonized with over 100 trillion beneficial, or commensal, bacteria of many different species. In healthy people, these bacteria are limited to the intestinal tissues and have a number of helpful properties, including aiding in the digestion of food and promoting a healthy immune system.
Immunology
Source: University of Pennsylvania School of Medicine
Posted on: Thursday, Jun 07, 2012, 10:45am
Rating: | Views: 1175 | Comments: 0
Source: University of Pennsylvania School of Medicine
Posted on: Thursday, Jun 07, 2012, 10:45am
Rating: | Views: 1175 | Comments: 0
'Simple and effective' injection could offer hope for treatment of autoimmune disease
Australian researchers have uncovered a potential new way to regulate the body's natural immune response, offering hope of a simple and effective new treatment for auto-immune diseases.
Australian researchers have uncovered a potential new way to regulate the body's natural immune response, offering hope of a simple and effective new treatment for auto-immune diseases.
Immunology
Source: University of New South Wales
Posted on: Thursday, May 31, 2012, 1:30pm
Rating: | Views: 1148 | Comments: 0
Source: University of New South Wales
Posted on: Thursday, May 31, 2012, 1:30pm
Rating: | Views: 1148 | Comments: 0
Scientists identify new HIV-inhibiting protein
Scientists have identified a new HIV-suppressing protein in the blood of people infected with the virus. In laboratory studies, the protein, called CXCL4 or PF-4, binds to HIV such that it cannot attach to or enter a human cell. The research was led by Paolo Lusso, M.D., Ph.D., chief of the Section of Viral Pathogenesis in the Laboratory of Immunoregulation at the National Institute of Allergy and
Scientists have identified a new HIV-suppressing protein in the blood of people infected with the virus. In laboratory studies, the protein, called CXCL4 or PF-4, binds to HIV such that it cannot attach to or enter a human cell. The research was led by Paolo Lusso, M.D., Ph.D., chief of the Section of Viral Pathogenesis in the Laboratory of Immunoregulation at the National Institute of Allergy and
Immunology
Source: NIH/National Institute of Allergy and Infectious Diseases
Posted on: Tuesday, May 29, 2012, 5:15pm
Rating: | Views: 1126 | Comments: 0
Source: NIH/National Institute of Allergy and Infectious Diseases
Posted on: Tuesday, May 29, 2012, 5:15pm
Rating: | Views: 1126 | Comments: 0
T cells 'hunt' parasites like animal predators seek prey
By pairing an intimate knowledge of immune-system function with a deep understanding of statistical physics, a cross-disciplinary team at the University of Pennsylvania has arrived at a surprising finding: T cells use a movement strategy to track down parasites that is similar to strategies that predators such as monkeys, sharks and blue-fin tuna use to hunt their prey.
By pairing an intimate knowledge of immune-system function with a deep understanding of statistical physics, a cross-disciplinary team at the University of Pennsylvania has arrived at a surprising finding: T cells use a movement strategy to track down parasites that is similar to strategies that predators such as monkeys, sharks and blue-fin tuna use to hunt their prey.
Immunology
Source: University of Pennsylvania
Posted on: Tuesday, May 29, 2012, 11:45am
Rating: | Views: 1145 | Comments: 0
Source: University of Pennsylvania
Posted on: Tuesday, May 29, 2012, 11:45am
Rating: | Views: 1145 | Comments: 0
Anti-inflammatory drugs may improve survival from severe malaria
A novel anti-inflammatory drug could help to improve survival in the most severe cases of malaria by preventing the immune system from causing irrevocable brain and tissue damage.
A novel anti-inflammatory drug could help to improve survival in the most severe cases of malaria by preventing the immune system from causing irrevocable brain and tissue damage.
Immunology
Source: Walter and Eliza Hall Institute
Posted on: Thursday, May 24, 2012, 1:15pm
Rating: | Views: 1251 | Comments: 0
Source: Walter and Eliza Hall Institute
Posted on: Thursday, May 24, 2012, 1:15pm
Rating: | Views: 1251 | Comments: 0
Type of viral infection of eye associated with disease causing blindness in the elderly
A team of researchers, including a scientist from the Viral Immunology Center at Georgia State University, have found that a type of herpesvirus infection of the eye is associated with neovascular age-related macular degeneration (AMD), a disease that causes blindness in the elderly.
A team of researchers, including a scientist from the Viral Immunology Center at Georgia State University, have found that a type of herpesvirus infection of the eye is associated with neovascular age-related macular degeneration (AMD), a disease that causes blindness in the elderly.
Molecular Biology
Source: Georgia State University
Posted on: Tuesday, May 22, 2012, 12:30pm
Rating: | Views: 1188 | Comments: 0
Source: Georgia State University
Posted on: Tuesday, May 22, 2012, 12:30pm
Rating: | Views: 1188 | Comments: 0
Arthritis drug a low cost treatment for amoebic infections, dysentery
A team of researchers from UCSF and UC San Diego has identified an approved arthritis drug that is effective against amoebas in lab and animal studies, suggesting it could offer a low-dose, low cost treatment for the amoebic infections that cause human dysentery throughout the world.
A team of researchers from UCSF and UC San Diego has identified an approved arthritis drug that is effective against amoebas in lab and animal studies, suggesting it could offer a low-dose, low cost treatment for the amoebic infections that cause human dysentery throughout the world.
Immunology
Source: University of California - San Francisco
Posted on: Monday, May 21, 2012, 8:45am
Rating: | Views: 1543 | Comments: 0
Source: University of California - San Francisco
Posted on: Monday, May 21, 2012, 8:45am
Rating: | Views: 1543 | Comments: 0
Delivery system for gene therapy may help treat arthritis
A DNA-covered submicroscopic bead used to deliver genes or drugs directly into cells to treat disease appears to have therapeutic value just by showing up, researchers report.
A DNA-covered submicroscopic bead used to deliver genes or drugs directly into cells to treat disease appears to have therapeutic value just by showing up, researchers report.
Immunology
Source: Georgia Health Sciences University
Posted on: Tuesday, May 15, 2012, 11:30am
Rating: | Views: 1131 | Comments: 0
Source: Georgia Health Sciences University
Posted on: Tuesday, May 15, 2012, 11:30am
Rating: | Views: 1131 | Comments: 0
Living longer: variability in infection-fighting genes can be a boon for male survival
Females of mammals (including humans) tend to outlive males, a circumstance that is usually attributed to males´ more aggressive and hence energy-depleting behaviour, especially when they compete for females. This might also explain why males of many species usually show a higher parasite burden than females. Therefore, high variability of immune genes, supposed to reduce susceptibility to pathoge
Females of mammals (including humans) tend to outlive males, a circumstance that is usually attributed to males´ more aggressive and hence energy-depleting behaviour, especially when they compete for females. This might also explain why males of many species usually show a higher parasite burden than females. Therefore, high variability of immune genes, supposed to reduce susceptibility to pathoge
Immunology
Source: University of Veterinary Medicine -- Vienna
Posted on: Monday, May 14, 2012, 8:15am
Rating: | Views: 1184 | Comments: 0
Source: University of Veterinary Medicine -- Vienna
Posted on: Monday, May 14, 2012, 8:15am
Rating: | Views: 1184 | Comments: 0
Research scientists show how memory B cells stay 'in class' to fight different infections
Scientists at The Scripps Research Institute have made an important discovery about the internal programming of B cells, the immune cells that make antibodies against infections. The finding opens the way for the development of vaccines that can work more efficiently and hints at therapies for conditions in which B cells cause harm—such as the autoimmune disease lupus
Scientists at The Scripps Research Institute have made an important discovery about the internal programming of B cells, the immune cells that make antibodies against infections. The finding opens the way for the development of vaccines that can work more efficiently and hints at therapies for conditions in which B cells cause harm—such as the autoimmune disease lupus
Immunology
Source: Scripps Research Institute
Posted on: Tuesday, May 08, 2012, 2:00pm
Rating: | Views: 1163 | Comments: 0
Source: Scripps Research Institute
Posted on: Tuesday, May 08, 2012, 2:00pm
Rating: | Views: 1163 | Comments: 0
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