New genetic test detects early breast cancer and identifies future risk Physicians may now be better at detecting breast cancer than ever before, but much more work remains to ensure accurate diagnosis is possible and especially to assess future risk. That's why researchers from Germany have been working to develop a new test of gene action to predict cancer risk both at first diagnosis and into the future. In a new research report appearing in the Decemb
Genetics Source: Federation of American Societies for Experimental Biology
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Friday, Nov 30, 2012, 11:45am Rating: | Views: 1802 | Comments: 0
Researchers create a fly to study how a normal cell turns cancerous The wing of a fruit fly may hold the key to unraveling the genetic and molecular events that transform a normal cell into a cancerous one. The study, conducted on Drosophila melanogaster by scientists at the Institute for Research in Biomedicine (IRB Barcelona) and led by ICREA researcher Marco Milán, has reproduced each of the steps known to take place when a healthy cell turns cancerous.
Cancer Source: Institute for Research in Biomedicine (IRB Barcelona)
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Friday, Nov 30, 2012, 10:30am Rating: | Views: 9861 | Comments: 0
Scientists uncover a novel cooperative effort to stop cancer spread Scientists from the Florida campus of The Scripps Research Institute (TSRI) have uncovered a group of what have been considered relatively minor regulators in the body that band together to suppress the spread of cancer from its primary site.
Cancer Source: Scripps Research Institute
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Thursday, Nov 29, 2012, 12:30pm Rating: | Views: 1225 | Comments: 0
Study points to potential new therapies for cancer and other diseases Researchers at The Scripps Research Institute (TRSI) are fueling the future of cancer treatment by improving a powerful tool in disease defense: the body's immune system. By revealing a novel but widespread cell signaling process, the scientists may have found a way to manipulate an important component of the immune system into more effectively fighting disease.
Molecular Biology Source: Scripps Research Institute
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Wednesday, Nov 28, 2012, 4:45pm Rating: | Views: 2323 | Comments: 0
Gene that causes tumor disorder linked to increased breast cancer risk New Johns Hopkins research showing a more than four-fold increase in the incidence of breast cancer in women with neurofibromatosis-1 (NF1) adds to growing evidence that women with this rare genetic disorder may benefit from early breast cancer screening with mammograms beginning at age 40, and manual breast exams as early as adolescence.
Genetics Source: Johns Hopkins Medicine
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Wednesday, Nov 28, 2012, 10:45am Rating: | Views: 2187 | Comments: 0
Novel mechanism through which normal stromal cells become cancer-promoting cells identified New understanding of molecular changes that convert harmless cells surrounding ovarian cancer cells into cells that promote tumor growth and metastasis provides potential new therapeutic targets for this deadly disease, according to data published in Cancer Discovery, a journal of the American Association for Cancer Research.
Biochemistry Source: American Association for Cancer Research
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Thursday, Nov 22, 2012, 11:00am Rating: | Views: 1233 | Comments: 0
Some cells don't know when to stop Certain mutated cells keep trying to replicate their DNA — with disastrous results — even after medications rob them of the raw materials to do so, according to new research from USC.
Cancer Source: University of Southern California
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Wednesday, Nov 21, 2012, 11:15am Rating: | Views: 1184 | Comments: 0
Research could halt melanoma metastasis In laboratory experiments, scientists have eliminated metastasis, the spread of cancer from the original tumor to other parts of the body, in melanoma by inhibiting a protein known as melanoma differentiation associated gene-9 (mda-9)/syntenin. More than 1 million cases of skin cancer are diagnosed each year in the U.S., and melanoma is the deadliest form. With
Cancer Source: Virginia Commonwealth University
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Friday, Nov 16, 2012, 2:45pm Rating: | Views: 1243 | Comments: 0
Cancer Source: St. Jude Children's Research Hospital
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Thursday, Nov 15, 2012, 8:30am Rating: | Views: 1174 | Comments: 0
Study shows how chronic inflammation can cause cancer A hormone-like substance produced by the body to promote inflammation can cause an aggressive form of leukemia when present at high levels, according to a new study by researchers at the Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James).
Cancer Source: Ohio State University Medical Center
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Wednesday, Nov 14, 2012, 5:45pm Rating: | Views: 1550 | Comments: 0
Researchers discover 2 genetic flaws behind common form of inherited muscular dystrophy An international research team co-led by a scientist at Fred Hutchinson Cancer Research Center has identified two genetic factors behind the third most common form of muscular dystrophy. The findings, published online in Nature Genetics, represent the latest in the team's series of groundbreaking discoveries begun in 2010 regarding the genetic causes of facioscapulohumeral muscular dystrophy, or F
Genetics Source: Fred Hutchinson Cancer Research Center
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Wednesday, Nov 14, 2012, 12:30pm Rating: | Views: 1189 | Comments: 0
Cancer Source: UT Southwestern Medical Center
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Thursday, Nov 08, 2012, 12:00pm Rating: | Views: 1293 | Comments: 0
Scientists find Achilles' heel of cancer cells Several substances inhibiting so-called HDAC enzymes have been studied in trials searching for new anti-cancer drugs in recent years. "Trials have shown that HDAC inhibitors are very effective in arresting growth of cultured cancer cells. But apart from a very rare type of lymphoma, these drugs unfortunately do not clinically affect malignant tumors," says Prof. Dr. Olaf Witt, who heads a research
Cancer Source: Helmholtz Association of German Research Centres
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Tuesday, Nov 06, 2012, 8:30am Rating: | Views: 1684 | Comments: 0
Unexpected factor contributes to melanoma risk in red-haired, fair-skinned individuals The well-established elevated risk of melanoma among people with red hair and fair skin may be caused by more than just a lack of natural protection against ultraviolet (UV) radiation. In an article receiving Advance Online Publication in Nature, Massachusetts General Hospital (MGH) Cutaneous Biology Research Center (CBRC)and Cancer Center researchers report finding that the type of skin pi
Cancer Source: Massachusetts General Hospital
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Thursday, Nov 01, 2012, 2:30pm Rating: | Views: 1234 | Comments: 0
Cancer, Heart Research Threatened By Power Outage At NYU Hospital Specially bred mice and rats perished in the flooding from Superstorm Sandy. Now cell lines and DNA stored in refrigerators and freezers might be dying as the temperature rises. The loss could set researchers back years.
Recent findings may help to fight melanoma's resistance to chemotherapy Blocking the action of a particular protein in our skin could improve the treatment of skin cancers, according to a study published in Oncogene yesterday by Philippe Roux, a researcher at the University of Montreal's Institute for Research in Immunology and Cancer (IRIC).
Cancer Source: University of Montreal
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Thursday, Nov 01, 2012, 8:15am Rating: | Views: 1225 | Comments: 0
Lactation protein suppresses tumors and metastasis in breast cancer A protein that is necessary for lactation in mammals inhibits the critical cellular transition that is an early indicator of breast cancer and metastasis, according to research conducted at the University at Buffalo and Princeton University and highlighted as the cover paper in November issue of Nature Cell Biology.
Cancer Source: University at Buffalo
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Thursday, Oct 25, 2012, 11:30am Rating: | Views: 1230 | Comments: 0
Moffitt researchers study how patterns, timing of sunlight exposure contribute to skin cancers Researchers at Moffitt Cancer Center, the University of South Florida and the International Agency for Research on Cancer in France have studied the patterns and timing of sunlight exposure and how each is related to two nonmelanoma skin cancers – basal cell carcinoma and squamous cell carcinoma.
Cancer Source: H. Lee Moffitt Cancer Center & Research Institute
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Wednesday, Oct 24, 2012, 10:00am Rating: | Views: 1265 | Comments: 0
Novel discovery links anti-cancer drugs to muscle repair Few drugs are available to treat muscle injury, muscle wasting and genetic disorders causing muscle degeneration, such as Duchenne muscular dystrophy. A compelling discovery that may change this was made recently by a research group led by Dr. Robert Korneluk, distinguished professor at University of Ottawa's Faculty of Medicine and founder of the CHEO Research Institute
Molecular Biology Source: Children's Hospital of Eastern Ontario Research Institute
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Wednesday, Oct 17, 2012, 11:30am Rating: | Views: 1160 | Comments: 0
Cancer Source: University of California - Los Angeles
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Tuesday, Oct 16, 2012, 4:45pm Rating: | Views: 1169 | Comments: 0
Study suggests how expanding waistlines may contribute to cancer Fat progenitor cells may contribute to cancer growth by fortifying the vessels that provide needed blood to tumors, according to preclinical research findings by investigators at The University of Texas Health Science Center at Houston (UTHealth).
Cancer Source: University of Texas Health Science Center at Houston
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Tuesday, Oct 16, 2012, 1:45pm Rating: | Views: 1220 | Comments: 0
Cells control energy metabolism via hedgehog signalling pathway Cancer, diabetes, and excess body weight have one thing in common: they alter cellular metabolism. Scientists from the Max Planck Institute of Immunobiology and Epigenetics in Freiburg and the Medical University of Vienna together with an international research team have jointly resolved a new molecular circuit controlling cellular metabolism.
Molecular Biology Source: Max-Planck-Gesellschaft
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Monday, Oct 15, 2012, 10:00am Rating: | Views: 1267 | Comments: 0
Melanoma - The wolf in sheep's clothing Melanoma is so dangerous because it tends to metastasize early on. New treatment approaches utilize, among other things, the ability of the immune defense to search out and destroy malignant cells. Yet this strategy is often only temporarily effective. A research team under the direction of Bonn University has discovered why this is the case: In the inflammatory reaction caused by the treatment, t
Cancer Source: University of Bonn
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Thursday, Oct 11, 2012, 1:15pm Rating: | Views: 1335 | Comments: 0
Squeezing ovarian cancer cells to predict metastatic potential New Georgia Tech research shows that cell stiffness could be a valuable clue for doctors as they search for and treat cancerous cells before they're able to spread. The findings, which are published in the journal PLoS One, found that highly metastatic ovarian cancer cells are several times softer than less metastatic ovarian cancer cells.
Cancer Source: Georgia Institute of Technology
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Thursday, Oct 11, 2012, 12:15pm Rating: | Views: 27774 | Comments: 0
A novel oncogenic network specific to liver cancer initiation Researchers headed by Erwin Wagner, the Director of the BBVA Foundation-CNIO Cancer Cell Biology Programme at the Spanish National Cancer Research Centre (CNIO), have deciphered how a stress-inducible gene regulator, AP-1, controls the survival of liver tumor-initiating cells. These results, published in the online edition of Nature Cell Biology, could provide new preventive strategies and
Cancer Source: Centro Nacional de Investigaciones Oncologicas (CNIO)
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Monday, Oct 08, 2012, 2:30pm Rating: | Views: 1175 | Comments: 0
Neuroscience Source: University of Guelph
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Monday, Oct 08, 2012, 10:45am Rating: | Views: 1160 | Comments: 0
Adult stem cells change their epigenome to generate new organs The team led by Manel Esteller, director of the Cancer Epigenetics and Biology Program in the Bellvitge Biomedical Research Institute (IDIBELL), Professor of Genetics at the University of Barcelona and ICREA researcher, has identified epigenetic changes that occur in adult stem cells to generate different body tissues. The finding is published this week in The American Journal of Pathology.
Stem cells Source: IDIBELL-Bellvitge Biomedical Research Institute
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Wednesday, Oct 03, 2012, 12:45pm Rating: | Views: 1159 | Comments: 0
Cancer Source: University of Sheffield
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Tuesday, Oct 02, 2012, 4:45pm Rating: | Views: 1116 | Comments: 0
Clonal evolution in Maxillary Sinus Carcinoma Knowing how tumors evolve can lead to new treatments that could help prevent cancer from recurring, according to a study published today by the Translational Genomics Research Institute (TGen) and Scottsdale Healthcare.
Cancer Source: The Translational Genomics Research Institute
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Monday, Oct 01, 2012, 1:45pm Rating: | Views: 1425 | Comments: 0
Team discovers the first real indicator of longevity in mammals A team of researchers from the Spanish National Cancer Research Centre (CNIO), headed by CNIO Director María Blasco, has demonstrated in a pioneering study on mammals that longevity is defined at a molecular level by the length of telomeres. The work—which is published today in the online edition of the journal Cell Reports—opens the door to further study of these cellular components in ord
Genetics Source: Centro Nacional de Investigaciones Oncologicas (CNIO)
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Friday, Sep 28, 2012, 11:45am Rating: | Views: 1356 | Comments: 0