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Synthetic Life Seeks Work
A startup company says it is expanding the language of DNA to create new tools for drug discovery.
A startup company says it is expanding the language of DNA to create new tools for drug discovery.
Biochemistry
Source: Technology Review
Posted on: Wednesday, Aug 19, 2015, 12:04pm
Rating: | Views: 3197 | Comments: 0
Source: Technology Review
Posted on: Wednesday, Aug 19, 2015, 12:04pm
Rating: | Views: 3197 | Comments: 0
Sushi Science: A 3-D View Of The Body's Wasabi Receptor
The same receptor on nerve endings that makes sinuses tingle when we eat wasabi plays an important role in the pain of inflammation. The first 3-D view of the receptor could lead to better pain drugs.
The same receptor on nerve endings that makes sinuses tingle when we eat wasabi plays an important role in the pain of inflammation. The first 3-D view of the receptor could lead to better pain drugs.
Biochemistry
Source: NPR
Posted on: Thursday, Apr 09, 2015, 8:08am
Rating: | Views: 1274 | Comments: 0
Source: NPR
Posted on: Thursday, Apr 09, 2015, 8:08am
Rating: | Views: 1274 | Comments: 0
Aspiring Craft Brewers Hit The Books To Pick Up Science Chops
As the craft beer industry grows, so are options for learning to brew. More colleges are now introducing degree programs to teach the art and science of beer-making.
As the craft beer industry grows, so are options for learning to brew. More colleges are now introducing degree programs to teach the art and science of beer-making.
Biochemistry
Source: NPR
Posted on: Wednesday, Apr 08, 2015, 10:52am
Rating: | Views: 1133 | Comments: 0
Source: NPR
Posted on: Wednesday, Apr 08, 2015, 10:52am
Rating: | Views: 1133 | Comments: 0
How mapping the human proteome reveals new insights into our bodies
Professor Kathryn Lilley explains the science behind recent progress in working out when and where our proteins are made
Professor Kathryn Lilley explains the science behind recent progress in working out when and where our proteins are made
Biochemistry
Source: TheGuardian
Posted on: Thursday, Jun 19, 2014, 9:11am
Rating: | Views: 1292 | Comments: 0
Source: TheGuardian
Posted on: Thursday, Jun 19, 2014, 9:11am
Rating: | Views: 1292 | Comments: 0
Chimera enzyme may make better biofuels from waste
Bacterial enzymes that would never have met in nature have been fused to create a chemical that can efficiently break down plant cellulose
Bacterial enzymes that would never have met in nature have been fused to create a chemical that can efficiently break down plant cellulose
Biochemistry
Source: New Scientist
Posted on: Wednesday, Jun 11, 2014, 8:35am
Rating: | Views: 1284 | Comments: 0
Source: New Scientist
Posted on: Wednesday, Jun 11, 2014, 8:35am
Rating: | Views: 1284 | Comments: 0
HIV inner shell structure revealed
Researchers have for the first time unravelled the complex structure of the inner protein shell of the HIV molecule.
Researchers have for the first time unravelled the complex structure of the inner protein shell of the HIV molecule.
Biochemistry
Source: BBC News
Posted on: Thursday, May 30, 2013, 7:37am
Rating: | Views: 1160 | Comments: 0
Source: BBC News
Posted on: Thursday, May 30, 2013, 7:37am
Rating: | Views: 1160 | Comments: 0
Vicious cycle: Obesity sustained by changes in brain biochemistry 
With obesity reaching epidemic levels in some parts of the world, scientists have only begun to understand why it is such a persistent condition. A study in the Journal of Biological Chemistry adds substantially to the story by reporting the discovery of a molecular chain of events in the brains of obese rats that undermined their ability to suppress ap
With obesity reaching epidemic levels in some parts of the world, scientists have only begun to understand why it is such a persistent condition. A study in the Journal of Biological Chemistry adds substantially to the story by reporting the discovery of a molecular chain of events in the brains of obese rats that undermined their ability to suppress ap
Neuroscience
Source: Brown University
Posted on: Friday, May 17, 2013, 12:00pm
Rating: | Views: 1971 | Comments: 0
Source: Brown University
Posted on: Friday, May 17, 2013, 12:00pm
Rating: | Views: 1971 | Comments: 0
Unleashing the watchdog protein
McGill University researchers have unlocked a new door to developing drugs to slow the progression of Parkinson's disease. Collaborating teams led by Dr. Edward A. Fon at the Montreal Neurological Institute and Hospital -The Neuro, and Dr. Kalle Gehring in the Department of Biochemistry at the Faculty of Medicine, have discovered the three-dimensional structure of the protein Parkin. Mutations i
McGill University researchers have unlocked a new door to developing drugs to slow the progression of Parkinson's disease. Collaborating teams led by Dr. Edward A. Fon at the Montreal Neurological Institute and Hospital -The Neuro, and Dr. Kalle Gehring in the Department of Biochemistry at the Faculty of Medicine, have discovered the three-dimensional structure of the protein Parkin. Mutations i
Biochemistry
Source: McGill University
Posted on: Monday, May 13, 2013, 12:00pm
Rating: | Views: 1501 | Comments: 0
Source: McGill University
Posted on: Monday, May 13, 2013, 12:00pm
Rating: | Views: 1501 | Comments: 0
Comparing proteins at a glance
A revolutionary X-ray analytical technique that enables researchers at a glance to identify structural similarities and differences between multiple proteins under a variety of conditions has been developed by researchers with the U.S. Department of Energy (DOE)'s Lawrence Berkeley National Laboratory (Berkeley Lab). As a demonstration, the researchers used this technique to gain valuable new insi
A revolutionary X-ray analytical technique that enables researchers at a glance to identify structural similarities and differences between multiple proteins under a variety of conditions has been developed by researchers with the U.S. Department of Energy (DOE)'s Lawrence Berkeley National Laboratory (Berkeley Lab). As a demonstration, the researchers used this technique to gain valuable new insi
Biochemistry
Source: DOE/Lawrence Berkeley National Laboratory
Posted on: Tuesday, Apr 30, 2013, 1:30pm
Rating: | Views: 1827 | Comments: 0
Source: DOE/Lawrence Berkeley National Laboratory
Posted on: Tuesday, Apr 30, 2013, 1:30pm
Rating: | Views: 1827 | Comments: 0
Thanks to rare alpine bacteria, researchers identify one of alcohol's key gateways to the brain
Thanks to a rare bacteria that grows only on rocks in the Swiss Alps, researchers at The University of Texas at Austin and the Pasteur Institute in France have been the first to identify how alcohol might affect key brain proteins.
Thanks to a rare bacteria that grows only on rocks in the Swiss Alps, researchers at The University of Texas at Austin and the Pasteur Institute in France have been the first to identify how alcohol might affect key brain proteins.
Biochemistry
Source: University of Texas at Austin
Posted on: Friday, Apr 26, 2013, 2:30pm
Rating: | Views: 1467 | Comments: 0
Source: University of Texas at Austin
Posted on: Friday, Apr 26, 2013, 2:30pm
Rating: | Views: 1467 | Comments: 0
Biofilms help Salmonella survive hostile conditions
Virginia Tech scientists have provided new evidence that biofilms — bacteria that adhere to surfaces and build protective coatings — are at work in the survival of the human pathogen Salmonella.
Virginia Tech scientists have provided new evidence that biofilms — bacteria that adhere to surfaces and build protective coatings — are at work in the survival of the human pathogen Salmonella.
Biochemistry
Source: Virginia Tech
Posted on: Thursday, Apr 11, 2013, 4:45pm
Rating: | Views: 1544 | Comments: 0
Source: Virginia Tech
Posted on: Thursday, Apr 11, 2013, 4:45pm
Rating: | Views: 1544 | Comments: 0
Exciting advance in search for neurodegenerative disease treatments
A significant breakthrough has been made by scientists at The University of Manchester towards developing an effective treatment for neurodegenerative diseases such as Huntington's, Alzheimer's and Parkinson's.
A significant breakthrough has been made by scientists at The University of Manchester towards developing an effective treatment for neurodegenerative diseases such as Huntington's, Alzheimer's and Parkinson's.
Biochemistry
Source: University of Manchester
Posted on: Thursday, Apr 11, 2013, 11:00am
Rating: | Views: 1386 | Comments: 0
Source: University of Manchester
Posted on: Thursday, Apr 11, 2013, 11:00am
Rating: | Views: 1386 | Comments: 0
Researcher offers clues on the origins of life
A structural biologist at the Florida State University College of Medicine has made discoveries that could lead scientists a step closer to understanding how life first emerged on Earth billions of years ago.
A structural biologist at the Florida State University College of Medicine has made discoveries that could lead scientists a step closer to understanding how life first emerged on Earth billions of years ago.
Biochemistry
Source: Florida State University
Posted on: Monday, Apr 08, 2013, 10:45am
Rating: | Views: 1307 | Comments: 0
Source: Florida State University
Posted on: Monday, Apr 08, 2013, 10:45am
Rating: | Views: 1307 | Comments: 0
Study provides new insight into photosynthesis
Pigments found in plants and purple bacteria employed to provide protection from sun damage do more than just that. Researchers from the University of Toronto and University of Glasgow have found that they also help to harvest light energy during photosynthesis.
Pigments found in plants and purple bacteria employed to provide protection from sun damage do more than just that. Researchers from the University of Toronto and University of Glasgow have found that they also help to harvest light energy during photosynthesis.
Biochemistry
Source: University of Toronto
Posted on: Friday, Apr 05, 2013, 10:45am
Rating: | Views: 1546 | Comments: 0
Source: University of Toronto
Posted on: Friday, Apr 05, 2013, 10:45am
Rating: | Views: 1546 | Comments: 0
Picking apart photosynthesis
Chemists at the California Institute of Technology (Caltech) and the Lawrence Berkeley National Laboratory believe they can now explain one of the remaining mysteries of photosynthesis, the chemical process by which plants convert sunlight into usable energy and generate the oxygen that we breathe. The finding suggests a new way of approaching the design of catalysts that drive th
Chemists at the California Institute of Technology (Caltech) and the Lawrence Berkeley National Laboratory believe they can now explain one of the remaining mysteries of photosynthesis, the chemical process by which plants convert sunlight into usable energy and generate the oxygen that we breathe. The finding suggests a new way of approaching the design of catalysts that drive th
Biochemistry
Source: California Institute of Technology
Posted on: Monday, Apr 01, 2013, 11:00am
Rating: | Views: 1844 | Comments: 0
Source: California Institute of Technology
Posted on: Monday, Apr 01, 2013, 11:00am
Rating: | Views: 1844 | Comments: 0
Scientists reveal quirky feature of Lyme disease bacteria
Scientists have confirmed that the pathogen that causes Lyme Disease—unlike any other known organism—can exist without iron, a metal that all other life needs to make proteins and enzymes. Instead of iron, the bacteria substitute manganese to make an essential enzyme, thus eluding immune system defenses that protect the body by starving pathogens of iron.
Scientists have confirmed that the pathogen that causes Lyme Disease—unlike any other known organism—can exist without iron, a metal that all other life needs to make proteins and enzymes. Instead of iron, the bacteria substitute manganese to make an essential enzyme, thus eluding immune system defenses that protect the body by starving pathogens of iron.
Biochemistry
Source: Woods Hole Oceanographic Institution
Posted on: Friday, Mar 22, 2013, 11:30am
Rating: | Views: 1463 | Comments: 0
Source: Woods Hole Oceanographic Institution
Posted on: Friday, Mar 22, 2013, 11:30am
Rating: | Views: 1463 | Comments: 0
Mechanical forces play key role in assembly and disassembly of an essential cell protein
Researchers have for the first time demonstrated that mechanical forces can control the depolymerization of actin, a critical protein that provides the major force-bearing structure in the cytoskeletons of cells. The research suggests that forces applied both externally and internally may play a much larger role than previously believed in regulating a range of processes inside cells.
Researchers have for the first time demonstrated that mechanical forces can control the depolymerization of actin, a critical protein that provides the major force-bearing structure in the cytoskeletons of cells. The research suggests that forces applied both externally and internally may play a much larger role than previously believed in regulating a range of processes inside cells.
Biochemistry
Source: Georgia Institute of Technology
Posted on: Thursday, Mar 21, 2013, 8:00am
Rating: | Views: 6012 | Comments: 0
Source: Georgia Institute of Technology
Posted on: Thursday, Mar 21, 2013, 8:00am
Rating: | Views: 6012 | Comments: 0
Normal prion protein regulates iron metabolism
An iron imbalance caused by prion proteins collecting in the brain is a likely cause of cell death in Creutzfeldt-Jakob disease (CJD), researchers at Case Western Reserve University School of Medicine have found.
An iron imbalance caused by prion proteins collecting in the brain is a likely cause of cell death in Creutzfeldt-Jakob disease (CJD), researchers at Case Western Reserve University School of Medicine have found.
Biochemistry
Source: Case Western Reserve University
Posted on: Thursday, Mar 14, 2013, 11:15am
Rating: | Views: 2156 | Comments: 1
Source: Case Western Reserve University
Posted on: Thursday, Mar 14, 2013, 11:15am
Rating: | Views: 2156 | Comments: 1
Discovery opens door to new drug options for serious diseases
Researchers have discovered how oxidative stress can turn to the dark side a cellular protein that's usually benign, and make it become a powerful, unwanted accomplice in neuronal death.
Researchers have discovered how oxidative stress can turn to the dark side a cellular protein that's usually benign, and make it become a powerful, unwanted accomplice in neuronal death.
Biochemistry
Source: Oregon State University
Posted on: Tuesday, Mar 05, 2013, 12:00pm
Rating: | Views: 1429 | Comments: 0
Source: Oregon State University
Posted on: Tuesday, Mar 05, 2013, 12:00pm
Rating: | Views: 1429 | Comments: 0
International consortium builds 'Google Map' of human metabolism
Building on earlier pioneering work by researchers at the University of California, San Diego, an international consortium of university researchers has produced the most comprehensive virtual reconstruction of human metabolism to date. Scientists could use the model, known as Recon 2, to identify causes of and new treatments for diseases like cancer, diabetes and even psychiatric and neurodegener
Building on earlier pioneering work by researchers at the University of California, San Diego, an international consortium of university researchers has produced the most comprehensive virtual reconstruction of human metabolism to date. Scientists could use the model, known as Recon 2, to identify causes of and new treatments for diseases like cancer, diabetes and even psychiatric and neurodegener
Biochemistry
Source: University of California - San Diego
Posted on: Monday, Mar 04, 2013, 1:15pm
Rating: | Views: 2009 | Comments: 0
Source: University of California - San Diego
Posted on: Monday, Mar 04, 2013, 1:15pm
Rating: | Views: 2009 | Comments: 0
Mutation altering stability of surface molecule in acid enables H5N1 infection of mammals
A single mutation in the H5N1 avian influenza virus that affects the pH at which the hemagglutinin surface protein is activated simultaneously reduces its capacity to infect ducks and enhances its capacity to grow in mice according to research published ahead of print today in the Journal of Virology.
A single mutation in the H5N1 avian influenza virus that affects the pH at which the hemagglutinin surface protein is activated simultaneously reduces its capacity to infect ducks and enhances its capacity to grow in mice according to research published ahead of print today in the Journal of Virology.
Biochemistry
Source: American Society for Microbiology
Posted on: Friday, Mar 01, 2013, 12:00pm
Rating: | Views: 1824 | Comments: 0
Source: American Society for Microbiology
Posted on: Friday, Mar 01, 2013, 12:00pm
Rating: | Views: 1824 | Comments: 0
Discoveries suggest icy cosmic start for amino acids and DNA ingredients
Using new technology at the telescope and in laboratories, researchers have discovered an important pair of prebiotic molecules in interstellar space. The discoveries indicate that some basic chemicals that are key steps on the way to life may have formed on dusty ice grains floating between the stars.
Using new technology at the telescope and in laboratories, researchers have discovered an important pair of prebiotic molecules in interstellar space. The discoveries indicate that some basic chemicals that are key steps on the way to life may have formed on dusty ice grains floating between the stars.
Biochemistry
Source: National Radio Astronomy Observatory
Posted on: Friday, Mar 01, 2013, 11:30am
Rating: | Views: 1703 | Comments: 0
Source: National Radio Astronomy Observatory
Posted on: Friday, Mar 01, 2013, 11:30am
Rating: | Views: 1703 | Comments: 0
Study led by NUS researchers proves the existence of 3 overstretched DNA structures
A team of researchers led by Associate Professor Yan Jie from the Department of Physics at the National University of Singapore (NUS) Faculty of Science has identified three new distinct overstretched deoxyribonucleic acid (DNA) structures caused by mechanical stretching. This discovery provides a clear answer to a long-running debate among scientists over the nature of DNA overstretching.
A team of researchers led by Associate Professor Yan Jie from the Department of Physics at the National University of Singapore (NUS) Faculty of Science has identified three new distinct overstretched deoxyribonucleic acid (DNA) structures caused by mechanical stretching. This discovery provides a clear answer to a long-running debate among scientists over the nature of DNA overstretching.
Biochemistry
Source: National University of Singapore
Posted on: Friday, Mar 01, 2013, 11:00am
Rating: | Views: 1511 | Comments: 0
Source: National University of Singapore
Posted on: Friday, Mar 01, 2013, 11:00am
Rating: | Views: 1511 | Comments: 0
Metal ions regulate terpenoid metabolism in insects
Max Planck scientists in Jena, Germany, have discovered an unusual regulation of enzymes that catalyze chain elongation in an important secondary metabolism, the terpenoid pathway.
Max Planck scientists in Jena, Germany, have discovered an unusual regulation of enzymes that catalyze chain elongation in an important secondary metabolism, the terpenoid pathway.
Biochemistry
Source: Max Planck Institute for Chemical Ecology
Posted on: Friday, Mar 01, 2013, 10:30am
Rating: | Views: 1710 | Comments: 0
Source: Max Planck Institute for Chemical Ecology
Posted on: Friday, Mar 01, 2013, 10:30am
Rating: | Views: 1710 | Comments: 0
Video: Changing shape makes chemotherapy drugs better at targeting cancer cells
Bioengineering researchers at University of California, Santa Barbara have found that changing the shape of chemotherapy drug nanoparticles from spherical to rod-shaped made them up to 10,000 times more effective at specifically targeting and delivering anti-cancer drugs to breast cancer cells.
Bioengineering researchers at University of California, Santa Barbara have found that changing the shape of chemotherapy drug nanoparticles from spherical to rod-shaped made them up to 10,000 times more effective at specifically targeting and delivering anti-cancer drugs to breast cancer cells.
Biochemistry
Source: University of California - Santa Barbara
Posted on: Thursday, Feb 28, 2013, 12:30pm
Rating: | Views: 2292 | Comments: 0
Source: University of California - Santa Barbara
Posted on: Thursday, Feb 28, 2013, 12:30pm
Rating: | Views: 2292 | Comments: 0
Modified protein could become first effective treatment for vitiligo
Loyola University Chicago Stritch School of Medicine researchers have developed a genetically modified protein that dramatically reverses the skin disorder vitiligo in mice, and has similar effects on immune responses in human skin tissue samples.
Loyola University Chicago Stritch School of Medicine researchers have developed a genetically modified protein that dramatically reverses the skin disorder vitiligo in mice, and has similar effects on immune responses in human skin tissue samples.
Biochemistry
Source: Loyola University Health System
Posted on: Thursday, Feb 28, 2013, 12:00pm
Rating: | Views: 7194 | Comments: 15
Source: Loyola University Health System
Posted on: Thursday, Feb 28, 2013, 12:00pm
Rating: | Views: 7194 | Comments: 15
Resurrection of 3-billion-year-old antibiotic-resistance proteins
Scientists are reporting "laboratory resurrections" of several 2-3-billion-year-old proteins that are ancient ancestors of the enzymes that enable today's antibiotic-resistant bacteria to shrug off huge doses of penicillins, cephalosporins and other modern drugs. The achievement, reported in the Journal of the American Chemical Society, opens the door to a scientific "replay" of the evoluti
Scientists are reporting "laboratory resurrections" of several 2-3-billion-year-old proteins that are ancient ancestors of the enzymes that enable today's antibiotic-resistant bacteria to shrug off huge doses of penicillins, cephalosporins and other modern drugs. The achievement, reported in the Journal of the American Chemical Society, opens the door to a scientific "replay" of the evoluti
Biochemistry
Source: American Chemical Society
Posted on: Thursday, Feb 28, 2013, 10:00am
Rating: | Views: 3272 | Comments: 0
Source: American Chemical Society
Posted on: Thursday, Feb 28, 2013, 10:00am
Rating: | Views: 3272 | Comments: 0
Researchers find controlling element of Huntington's disease
Huntington's disease, also known as Huntington's chorea, is a hereditary brain disease causing movement disorders and dementia. In Germany, there are about 8,000 patients affected by Huntington's disease, with several hundred new cases arising every year. The disease usually manifests between the ages of 35 and 50. To date, it is incurable and inevitably leads to death. It is caused by a specific
Huntington's disease, also known as Huntington's chorea, is a hereditary brain disease causing movement disorders and dementia. In Germany, there are about 8,000 patients affected by Huntington's disease, with several hundred new cases arising every year. The disease usually manifests between the ages of 35 and 50. To date, it is incurable and inevitably leads to death. It is caused by a specific
Biochemistry
Source: Helmholtz Association of German Research Centres
Posted on: Wednesday, Feb 27, 2013, 10:30am
Rating: | Views: 1458 | Comments: 0
Source: Helmholtz Association of German Research Centres
Posted on: Wednesday, Feb 27, 2013, 10:30am
Rating: | Views: 1458 | Comments: 0
Scientists unveil secrets of important natural antibiotic
An international team of scientists has discovered how an important natural antibiotic called dermcidin, produced by our skin when we sweat, is a highly efficient tool to fight tuberculosis germs and other dangerous bugs.
An international team of scientists has discovered how an important natural antibiotic called dermcidin, produced by our skin when we sweat, is a highly efficient tool to fight tuberculosis germs and other dangerous bugs.
Biochemistry
Source: University of Edinburgh
Posted on: Friday, Feb 22, 2013, 10:30am
Rating: | Views: 1423 | Comments: 0
Source: University of Edinburgh
Posted on: Friday, Feb 22, 2013, 10:30am
Rating: | Views: 1423 | Comments: 0
Not just cars, but living organisms need antifreeze to survive
If you thought antifreeze was only something that was necessary to keep your car from freezing up in the winter, think again. Plants and animals living in cold climates have natural antifreeze proteins (AFPs) which prevent ice growth and crystallization of organic fluid matter. Without such antifreeze, living matter would suffer from frost damage and even death.
If you thought antifreeze was only something that was necessary to keep your car from freezing up in the winter, think again. Plants and animals living in cold climates have natural antifreeze proteins (AFPs) which prevent ice growth and crystallization of organic fluid matter. Without such antifreeze, living matter would suffer from frost damage and even death.
Biochemistry
Source: The Hebrew University of Jerusalem
Posted on: Tuesday, Feb 19, 2013, 12:30pm
Rating: | Views: 1513 | Comments: 0
Source: The Hebrew University of Jerusalem
Posted on: Tuesday, Feb 19, 2013, 12:30pm
Rating: | Views: 1513 | Comments: 0
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