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Synthetic Life Seeks Work A startup company says it is expanding the language of DNA to create new tools for drug discovery.
Biochemistry Source: Technology Review
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Wednesday, Aug 19, 2015, 12:04pm Rating: | Views: 3345 | Comments: 0
Sushi Science: A 3-D View Of The Body's Wasabi Receptor The same receptor on nerve endings that makes sinuses tingle when we eat wasabi plays an important role in the pain of inflammation. The first 3-D view of the receptor could lead to better pain drugs.
Biochemistry Source: New Scientist
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Wednesday, Jun 11, 2014, 8:35am Rating: | Views: 1295 | Comments: 0
HIV inner shell structure revealed Researchers have for the first time unravelled the complex structure of the inner protein shell of the HIV molecule.
Biochemistry Source: BBC News
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Thursday, May 30, 2013, 7:37am Rating: | Views: 1172 | Comments: 0
Vicious cycle: Obesity sustained by changes in brain biochemistry With obesity reaching epidemic levels in some parts of the world, scientists have only begun to understand why it is such a persistent condition. A study in the Journal of Biological Chemistry adds substantially to the story by reporting the discovery of a molecular chain of events in the brains of obese rats that undermined their ability to suppress ap
Neuroscience Source: Brown University
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Friday, May 17, 2013, 12:00pm Rating: | Views: 1981 | Comments: 0
Unleashing the watchdog protein McGill University researchers have unlocked a new door to developing drugs to slow the progression of Parkinson's disease. Collaborating teams led by Dr. Edward A. Fon at the Montreal Neurological Institute and Hospital -The Neuro, and Dr. Kalle Gehring in the Department of Biochemistry at the Faculty of Medicine, have discovered the three-dimensional structure of the protein Parkin. Mutations i
Biochemistry Source: McGill University
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Monday, May 13, 2013, 12:00pm Rating: | Views: 1511 | Comments: 0
Comparing proteins at a glance A revolutionary X-ray analytical technique that enables researchers at a glance to identify structural similarities and differences between multiple proteins under a variety of conditions has been developed by researchers with the U.S. Department of Energy (DOE)'s Lawrence Berkeley National Laboratory (Berkeley Lab). As a demonstration, the researchers used this technique to gain valuable new insi
Biochemistry Source: DOE/Lawrence Berkeley National Laboratory
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Tuesday, Apr 30, 2013, 1:30pm Rating: | Views: 1840 | Comments: 0
Biochemistry Source: University of Texas at Austin
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Friday, Apr 26, 2013, 2:30pm Rating: | Views: 1477 | Comments: 0
Biofilms help Salmonella survive hostile conditions Virginia Tech scientists have provided new evidence that biofilms — bacteria that adhere to surfaces and build protective coatings — are at work in the survival of the human pathogen Salmonella.
Biochemistry Source: Virginia Tech
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Thursday, Apr 11, 2013, 4:45pm Rating: | Views: 1555 | Comments: 0
Exciting advance in search for neurodegenerative disease treatments A significant breakthrough has been made by scientists at The University of Manchester towards developing an effective treatment for neurodegenerative diseases such as Huntington's, Alzheimer's and Parkinson's.
Biochemistry Source: University of Manchester
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Thursday, Apr 11, 2013, 11:00am Rating: | Views: 1396 | Comments: 0
Researcher offers clues on the origins of life A structural biologist at the Florida State University College of Medicine has made discoveries that could lead scientists a step closer to understanding how life first emerged on Earth billions of years ago.
Biochemistry Source: Florida State University
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Monday, Apr 08, 2013, 10:45am Rating: | Views: 1320 | Comments: 0
Study provides new insight into photosynthesis Pigments found in plants and purple bacteria employed to provide protection from sun damage do more than just that. Researchers from the University of Toronto and University of Glasgow have found that they also help to harvest light energy during photosynthesis.
Biochemistry Source: University of Toronto
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Friday, Apr 05, 2013, 10:45am Rating: | Views: 1556 | Comments: 0
Picking apart photosynthesis Chemists at the California Institute of Technology (Caltech) and the Lawrence Berkeley National Laboratory believe they can now explain one of the remaining mysteries of photosynthesis, the chemical process by which plants convert sunlight into usable energy and generate the oxygen that we breathe. The finding suggests a new way of approaching the design of catalysts that drive th
Biochemistry Source: California Institute of Technology
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Monday, Apr 01, 2013, 11:00am Rating: | Views: 1854 | Comments: 0
Scientists reveal quirky feature of Lyme disease bacteria Scientists have confirmed that the pathogen that causes Lyme Disease—unlike any other known organism—can exist without iron, a metal that all other life needs to make proteins and enzymes. Instead of iron, the bacteria substitute manganese to make an essential enzyme, thus eluding immune system defenses that protect the body by starving pathogens of iron.
Biochemistry Source: Woods Hole Oceanographic Institution
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Friday, Mar 22, 2013, 11:30am Rating: | Views: 1473 | Comments: 0
Mechanical forces play key role in assembly and disassembly of an essential cell protein Researchers have for the first time demonstrated that mechanical forces can control the depolymerization of actin, a critical protein that provides the major force-bearing structure in the cytoskeletons of cells. The research suggests that forces applied both externally and internally may play a much larger role than previously believed in regulating a range of processes inside cells.
Biochemistry Source: Georgia Institute of Technology
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Thursday, Mar 21, 2013, 8:00am Rating: | Views: 6022 | Comments: 0
Normal prion protein regulates iron metabolism An iron imbalance caused by prion proteins collecting in the brain is a likely cause of cell death in Creutzfeldt-Jakob disease (CJD), researchers at Case Western Reserve University School of Medicine have found.
Biochemistry Source: Case Western Reserve University
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Thursday, Mar 14, 2013, 11:15am Rating: | Views: 2168 | Comments: 1
Discovery opens door to new drug options for serious diseases Researchers have discovered how oxidative stress can turn to the dark side a cellular protein that's usually benign, and make it become a powerful, unwanted accomplice in neuronal death.
Biochemistry Source: Oregon State University
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Tuesday, Mar 05, 2013, 12:00pm Rating: | Views: 1439 | Comments: 0
International consortium builds 'Google Map' of human metabolism Building on earlier pioneering work by researchers at the University of California, San Diego, an international consortium of university researchers has produced the most comprehensive virtual reconstruction of human metabolism to date. Scientists could use the model, known as Recon 2, to identify causes of and new treatments for diseases like cancer, diabetes and even psychiatric and neurodegener
Biochemistry Source: University of California - San Diego
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Monday, Mar 04, 2013, 1:15pm Rating: | Views: 2026 | Comments: 0
Mutation altering stability of surface molecule in acid enables H5N1 infection of mammals A single mutation in the H5N1 avian influenza virus that affects the pH at which the hemagglutinin surface protein is activated simultaneously reduces its capacity to infect ducks and enhances its capacity to grow in mice according to research published ahead of print today in the Journal of Virology.
Biochemistry Source: American Society for Microbiology
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Friday, Mar 01, 2013, 12:00pm Rating: | Views: 1834 | Comments: 0
Discoveries suggest icy cosmic start for amino acids and DNA ingredients Using new technology at the telescope and in laboratories, researchers have discovered an important pair of prebiotic molecules in interstellar space. The discoveries indicate that some basic chemicals that are key steps on the way to life may have formed on dusty ice grains floating between the stars.
Biochemistry Source: National Radio Astronomy Observatory
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Friday, Mar 01, 2013, 11:30am Rating: | Views: 1714 | Comments: 0
Study led by NUS researchers proves the existence of 3 overstretched DNA structures A team of researchers led by Associate Professor Yan Jie from the Department of Physics at the National University of Singapore (NUS) Faculty of Science has identified three new distinct overstretched deoxyribonucleic acid (DNA) structures caused by mechanical stretching. This discovery provides a clear answer to a long-running debate among scientists over the nature of DNA overstretching.
Biochemistry Source: National University of Singapore
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Friday, Mar 01, 2013, 11:00am Rating: | Views: 1522 | Comments: 0
Metal ions regulate terpenoid metabolism in insects Max Planck scientists in Jena, Germany, have discovered an unusual regulation of enzymes that catalyze chain elongation in an important secondary metabolism, the terpenoid pathway.
Biochemistry Source: Max Planck Institute for Chemical Ecology
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Friday, Mar 01, 2013, 10:30am Rating: | Views: 1720 | Comments: 0
Video: Changing shape makes chemotherapy drugs better at targeting cancer cells Bioengineering researchers at University of California, Santa Barbara have found that changing the shape of chemotherapy drug nanoparticles from spherical to rod-shaped made them up to 10,000 times more effective at specifically targeting and delivering anti-cancer drugs to breast cancer cells.
Biochemistry Source: University of California - Santa Barbara
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Thursday, Feb 28, 2013, 12:30pm Rating: | Views: 2303 | Comments: 0
Modified protein could become first effective treatment for vitiligo Loyola University Chicago Stritch School of Medicine researchers have developed a genetically modified protein that dramatically reverses the skin disorder vitiligo in mice, and has similar effects on immune responses in human skin tissue samples.
Biochemistry Source: Loyola University Health System
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Thursday, Feb 28, 2013, 12:00pm Rating: | Views: 7238 | Comments: 15
Resurrection of 3-billion-year-old antibiotic-resistance proteins Scientists are reporting "laboratory resurrections" of several 2-3-billion-year-old proteins that are ancient ancestors of the enzymes that enable today's antibiotic-resistant bacteria to shrug off huge doses of penicillins, cephalosporins and other modern drugs. The achievement, reported in the Journal of the American Chemical Society, opens the door to a scientific "replay" of the evoluti
Biochemistry Source: American Chemical Society
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Thursday, Feb 28, 2013, 10:00am Rating: | Views: 3284 | Comments: 0
Researchers find controlling element of Huntington's disease Huntington's disease, also known as Huntington's chorea, is a hereditary brain disease causing movement disorders and dementia. In Germany, there are about 8,000 patients affected by Huntington's disease, with several hundred new cases arising every year. The disease usually manifests between the ages of 35 and 50. To date, it is incurable and inevitably leads to death. It is caused by a specific
Biochemistry Source: Helmholtz Association of German Research Centres
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Wednesday, Feb 27, 2013, 10:30am Rating: | Views: 1469 | Comments: 0
Scientists unveil secrets of important natural antibiotic An international team of scientists has discovered how an important natural antibiotic called dermcidin, produced by our skin when we sweat, is a highly efficient tool to fight tuberculosis germs and other dangerous bugs.
Biochemistry Source: University of Edinburgh
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Friday, Feb 22, 2013, 10:30am Rating: | Views: 1434 | Comments: 0
Not just cars, but living organisms need antifreeze to survive If you thought antifreeze was only something that was necessary to keep your car from freezing up in the winter, think again. Plants and animals living in cold climates have natural antifreeze proteins (AFPs) which prevent ice growth and crystallization of organic fluid matter. Without such antifreeze, living matter would suffer from frost damage and even death.
Biochemistry Source: The Hebrew University of Jerusalem
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Tuesday, Feb 19, 2013, 12:30pm Rating: | Views: 1524 | Comments: 0