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Discarded data may hold the key to a sharper view of molecules 
There's nothing like a new pair of eyeglasses to bring fine details into sharp relief. For scientists who study the large molecules of life from proteins to DNA, the equivalent of new lenses have come in the form of an advanced method for analyzing data from X-ray crystallography experiments.
There's nothing like a new pair of eyeglasses to bring fine details into sharp relief. For scientists who study the large molecules of life from proteins to DNA, the equivalent of new lenses have come in the form of an advanced method for analyzing data from X-ray crystallography experiments.
Biochemistry
Source: Oregon State University
Posted on: Friday, May 25, 2012, 12:45pm
Rating: | Views: 1095 | Comments: 0
Source: Oregon State University
Posted on: Friday, May 25, 2012, 12:45pm
Rating: | Views: 1095 | Comments: 0
Researchers identify protein necessary for behavioral flexibility
Researchers have identified a protein necessary to maintain behavioral flexibility, which allows us to modify our behaviors to adjust to circumstances that are similar, but not identical, to previous experiences. Their findings, which appear in the journal Cell Reports, may offer new insights into addressing autism and schizophrenia—afflictions marked by impaired behavioral flexibility.
Researchers have identified a protein necessary to maintain behavioral flexibility, which allows us to modify our behaviors to adjust to circumstances that are similar, but not identical, to previous experiences. Their findings, which appear in the journal Cell Reports, may offer new insights into addressing autism and schizophrenia—afflictions marked by impaired behavioral flexibility.
Biochemistry
Source: New York University
Posted on: Thursday, May 24, 2012, 5:45pm
Rating: | Views: 1282 | Comments: 0
Source: New York University
Posted on: Thursday, May 24, 2012, 5:45pm
Rating: | Views: 1282 | Comments: 0
A non-invasive intracellular 'thermometer' with fluorescent proteins has been created
A team from the Institute of Photonic Sciences (ICFO) has developed a technique to measure internal cell temperatures without altering their metabolism. This finding could be useful when distinguishing healthy cells from cancerous ones, as well as learning more about cellular processes.
A team from the Institute of Photonic Sciences (ICFO) has developed a technique to measure internal cell temperatures without altering their metabolism. This finding could be useful when distinguishing healthy cells from cancerous ones, as well as learning more about cellular processes.
Biochemistry
Source: FECYT - Spanish Foundation for Science and Technology
Posted on: Wednesday, May 23, 2012, 2:30pm
Rating: | Views: 1360 | Comments: 0
Source: FECYT - Spanish Foundation for Science and Technology
Posted on: Wednesday, May 23, 2012, 2:30pm
Rating: | Views: 1360 | Comments: 0
Biological clock began ticking 2.5 billion years ago
An enzyme found in nearly all forms of life runs on a 24-hour clock and dates back to a pivotal moment in evolution
An enzyme found in nearly all forms of life runs on a 24-hour clock and dates back to a pivotal moment in evolution
Biochemistry
Source: New Scientist
Posted on: Thursday, May 17, 2012, 7:58am
Rating: | Views: 1074 | Comments: 0
Source: New Scientist
Posted on: Thursday, May 17, 2012, 7:58am
Rating: | Views: 1074 | Comments: 0
Cellular secrets of plant fatty acid production understood
A curious twist in a family of plant proteins called chalcone-isomerase recently was discovered by Salk Institute for Biological Studies scientist Joseph Noel and colleagues at Iowa State University led by Eve Wurtele.
A curious twist in a family of plant proteins called chalcone-isomerase recently was discovered by Salk Institute for Biological Studies scientist Joseph Noel and colleagues at Iowa State University led by Eve Wurtele.
Biochemistry
Source: National Science Foundation
Posted on: Monday, May 14, 2012, 1:45pm
Rating: | Views: 1120 | Comments: 0
Source: National Science Foundation
Posted on: Monday, May 14, 2012, 1:45pm
Rating: | Views: 1120 | Comments: 0
The biochemistry of love and empathy
Neuroeconomist Paul Zak tells how his curiosity about morality led him on a biochemical hunt for oxytocin.
Neuroeconomist Paul Zak tells how his curiosity about morality led him on a biochemical hunt for oxytocin.
Neuroscience
Source: New Scientist
Posted on: Thursday, May 10, 2012, 9:07am
Rating: | Views: 1108 | Comments: 0
Source: New Scientist
Posted on: Thursday, May 10, 2012, 9:07am
Rating: | Views: 1108 | Comments: 0
Scientists discover enzyme that could slow part of the aging process in astronauts -- and the elderly
New research published online in the FASEB Journal suggests that a specific enzyme, called 5-lipoxygenase, plays a key role in cell death induced by microgravity environments, and that inhibiting this enzyme will likely help prevent or lessen the severity of immune problems in astronauts caused by spaceflight. Additionally, since space conditions initiate health problems that mimic the agi
New research published online in the FASEB Journal suggests that a specific enzyme, called 5-lipoxygenase, plays a key role in cell death induced by microgravity environments, and that inhibiting this enzyme will likely help prevent or lessen the severity of immune problems in astronauts caused by spaceflight. Additionally, since space conditions initiate health problems that mimic the agi
Biochemistry
Source: Federation of American Societies for Experimental Biology
Posted on: Monday, Apr 30, 2012, 4:15pm
Rating: | Views: 1238 | Comments: 0
Source: Federation of American Societies for Experimental Biology
Posted on: Monday, Apr 30, 2012, 4:15pm
Rating: | Views: 1238 | Comments: 0
Doubling the information from the double helix
Our genes control many aspects of who we are — from the colour of our hair to our vulnerability to certain diseases — but how are the genes, and consequently the proteins they make themselves controlled?
Our genes control many aspects of who we are — from the colour of our hair to our vulnerability to certain diseases — but how are the genes, and consequently the proteins they make themselves controlled?
Biochemistry
Source: University of Bristol
Posted on: Monday, Apr 30, 2012, 10:00am
Rating: | Views: 1110 | Comments: 0
Source: University of Bristol
Posted on: Monday, Apr 30, 2012, 10:00am
Rating: | Views: 1110 | Comments: 0
Scientists find the structure of a key 'gene silencer' protein
Scientists at The Scripps Research Institute have determined the three-dimensional atomic structure of a human protein that is centrally involved in regulating the activities of cells. Knowing the precise structure of this protein paves the way for scientists to understand a process known as RNA-silencing and to harness it to treat diseases.
Scientists at The Scripps Research Institute have determined the three-dimensional atomic structure of a human protein that is centrally involved in regulating the activities of cells. Knowing the precise structure of this protein paves the way for scientists to understand a process known as RNA-silencing and to harness it to treat diseases.
Biochemistry
Source: Scripps Research Institute
Posted on: Friday, Apr 27, 2012, 4:45pm
Rating: | Views: 1276 | Comments: 0
Source: Scripps Research Institute
Posted on: Friday, Apr 27, 2012, 4:45pm
Rating: | Views: 1276 | Comments: 0
Small molecular bodyguards kill HPV-infected cancer cells by protecting tumor-suppressor
Researchers at The Wistar Institute announce the discovery of small molecules that kill cancer cells caused by infection with human papillomavirus (HPV). Their results, in both cell and mouse models, demonstrate that the small molecule inhibitors protect a tumor-suppressing protein targeted by viral proteins, thus killing the infected tumor cells.
Researchers at The Wistar Institute announce the discovery of small molecules that kill cancer cells caused by infection with human papillomavirus (HPV). Their results, in both cell and mouse models, demonstrate that the small molecule inhibitors protect a tumor-suppressing protein targeted by viral proteins, thus killing the infected tumor cells.
Biochemistry
Source: The Wistar Institute
Posted on: Friday, Apr 27, 2012, 2:15pm
Rating: | Views: 1319 | Comments: 0
Source: The Wistar Institute
Posted on: Friday, Apr 27, 2012, 2:15pm
Rating: | Views: 1319 | Comments: 0
Identified 115 proteins that would allow designing new generation anti-cancer drugs
Researchers from the Research Programme in Biomedical Informatics (GRIB) from the IMIM (Hospital del Mar Research Institute) and the Pompeu Fabra University (UPF) have identified 115 proteins in silico (via computer simulation) that could be highly relevant to treat colon-rectal cancer, since they would make it possible to define the strategy to design new generation anti-cancer drugs. During the
Researchers from the Research Programme in Biomedical Informatics (GRIB) from the IMIM (Hospital del Mar Research Institute) and the Pompeu Fabra University (UPF) have identified 115 proteins in silico (via computer simulation) that could be highly relevant to treat colon-rectal cancer, since they would make it possible to define the strategy to design new generation anti-cancer drugs. During the
Biochemistry
Source: IMIM (Hospital del Mar Research Institute)
Posted on: Friday, Apr 27, 2012, 8:15am
Rating: | Views: 1240 | Comments: 0
Source: IMIM (Hospital del Mar Research Institute)
Posted on: Friday, Apr 27, 2012, 8:15am
Rating: | Views: 1240 | Comments: 0
Researchers create first custom designed protein crystal
Protein design is technique that is increasingly valuable to a variety of fields, from biochemistry to therapeutics to materials engineering. University of Pennsylvania chemists have taken this kind of design a step further; using computational methods, they have created the first custom-designed protein crystal.
Protein design is technique that is increasingly valuable to a variety of fields, from biochemistry to therapeutics to materials engineering. University of Pennsylvania chemists have taken this kind of design a step further; using computational methods, they have created the first custom-designed protein crystal.
Chemistry
Source: University of Pennsylvania
Posted on: Thursday, Apr 26, 2012, 10:30am
Rating: | Views: 1146 | Comments: 0
Source: University of Pennsylvania
Posted on: Thursday, Apr 26, 2012, 10:30am
Rating: | Views: 1146 | Comments: 0
In protein folding, internal friction may play a more significant role than previously thought
An international team of researchers has reported a new understanding of a little-known process that happens in virtually every cell of our bodies.
An international team of researchers has reported a new understanding of a little-known process that happens in virtually every cell of our bodies.
Biochemistry
Source: University of California - Santa Barbara
Posted on: Wednesday, Apr 25, 2012, 1:00pm
Rating: | Views: 1312 | Comments: 0
Source: University of California - Santa Barbara
Posted on: Wednesday, Apr 25, 2012, 1:00pm
Rating: | Views: 1312 | Comments: 0
Unusual protein helps regulate key cell communication pathway
Tiny pores, or channels, embedded in cell membranes are critical to the healthy functioning of cells. Charged atoms, or ions, move through these channels to generate the electrical signals that allow cells to communicate with one another.
Tiny pores, or channels, embedded in cell membranes are critical to the healthy functioning of cells. Charged atoms, or ions, move through these channels to generate the electrical signals that allow cells to communicate with one another.
Biochemistry
Source: Washington University School of Medicine
Posted on: Tuesday, Apr 24, 2012, 11:15am
Rating: | Views: 1161 | Comments: 0
Source: Washington University School of Medicine
Posted on: Tuesday, Apr 24, 2012, 11:15am
Rating: | Views: 1161 | Comments: 0
Microscopy yields first proof of ferroelectricity in simplest amino acid
The boundary between electronics and biology is blurring with the first detection by researchers at Department of Energy's Oak Ridge National Laboratory of ferroelectric properties in an amino acid called glycine.
The boundary between electronics and biology is blurring with the first detection by researchers at Department of Energy's Oak Ridge National Laboratory of ferroelectric properties in an amino acid called glycine.
Biochemistry
Source: DOE/Oak Ridge National Laboratory
Posted on: Friday, Apr 20, 2012, 8:15am
Rating: | Views: 1194 | Comments: 0
Source: DOE/Oak Ridge National Laboratory
Posted on: Friday, Apr 20, 2012, 8:15am
Rating: | Views: 1194 | Comments: 0
Process improves catalytic rate of enzymes by 3,000 percent
Light of specific wavelengths can be used to boost an enzyme's function by as much as 30 fold, potentially establishing a path to less expensive biofuels, detergents and a host of other products.
Light of specific wavelengths can be used to boost an enzyme's function by as much as 30 fold, potentially establishing a path to less expensive biofuels, detergents and a host of other products.
Biochemistry
Source: DOE/Oak Ridge National Laboratory
Posted on: Wednesday, Apr 18, 2012, 10:00am
Rating: | Views: 1379 | Comments: 0
Source: DOE/Oak Ridge National Laboratory
Posted on: Wednesday, Apr 18, 2012, 10:00am
Rating: | Views: 1379 | Comments: 0
Researchers solve 70-year-old mystery of how fungi synthesize topolone
In 1942, an 'unidentifiable' aromatic compound known as stipitatic acid was first isolated from fungi. By 1945 the structure was solved but it was so unique that it caused a revolution in the understanding of organic chemistry.
In 1942, an 'unidentifiable' aromatic compound known as stipitatic acid was first isolated from fungi. By 1945 the structure was solved but it was so unique that it caused a revolution in the understanding of organic chemistry.
Biochemistry
Source: University of Bristol
Posted on: Tuesday, Apr 17, 2012, 10:00am
Rating: | Views: 4444 | Comments: 0
Source: University of Bristol
Posted on: Tuesday, Apr 17, 2012, 10:00am
Rating: | Views: 4444 | Comments: 0
Study dusts sugar coating off little-known regulation in cells
In Alzheimer's disease, brain neurons become clogged with tangled proteins. Scientists suspect these tangles arise partly due to malfunctions in a little-known regulatory system within cells. Now, researchers have dramatically increased what they know about this particular regulatory system in mice. Such information will help scientists better understand Alzheimer's and other di
In Alzheimer's disease, brain neurons become clogged with tangled proteins. Scientists suspect these tangles arise partly due to malfunctions in a little-known regulatory system within cells. Now, researchers have dramatically increased what they know about this particular regulatory system in mice. Such information will help scientists better understand Alzheimer's and other di
Biochemistry
Source: DOE/Pacific Northwest National Laboratory
Posted on: Tuesday, Apr 17, 2012, 8:45am
Rating: | Views: 1197 | Comments: 0
Source: DOE/Pacific Northwest National Laboratory
Posted on: Tuesday, Apr 17, 2012, 8:45am
Rating: | Views: 1197 | Comments: 0
Enzyme in saliva helps regulate blood glucose
Scientists from the Monell Center report that blood glucose levels following starch ingestion are influenced by genetically-determined differences in salivary amylase, an enzyme that breaks down dietary starches. Specifically, higher salivary amylase activity is related to lower blood glucose.
Scientists from the Monell Center report that blood glucose levels following starch ingestion are influenced by genetically-determined differences in salivary amylase, an enzyme that breaks down dietary starches. Specifically, higher salivary amylase activity is related to lower blood glucose.
Biochemistry
Source: Monell Chemical Senses Center
Posted on: Thursday, Apr 05, 2012, 12:30pm
Rating: | Views: 4014 | Comments: 0
Source: Monell Chemical Senses Center
Posted on: Thursday, Apr 05, 2012, 12:30pm
Rating: | Views: 4014 | Comments: 0
Red wine, fruit compound could help block fat cell formation
A compound found in red wine, grapes and other fruits, and similar in structure to resveratrol, is able to block cellular processes that allow fat cells to develop, opening a door to a potential method to control obesity, according to a Purdue University study.
A compound found in red wine, grapes and other fruits, and similar in structure to resveratrol, is able to block cellular processes that allow fat cells to develop, opening a door to a potential method to control obesity, according to a Purdue University study.
Biochemistry
Source: Purdue University
Posted on: Thursday, Apr 05, 2012, 10:15am
Rating: | Views: 1346 | Comments: 0
Source: Purdue University
Posted on: Thursday, Apr 05, 2012, 10:15am
Rating: | Views: 1346 | Comments: 0
Scientists study the catalytic reactions used by plants to split oxygen from water
Splitting hydrogen and oxygen from water using conventional electrolysis techniques requires considerable amounts of electrical energy. But green plants produce oxygen from water efficiently using a catalytic technique powered by sunlight – a process that is part of photosynthesis and so effective that it is the Earth's major source of oxygen.
Splitting hydrogen and oxygen from water using conventional electrolysis techniques requires considerable amounts of electrical energy. But green plants produce oxygen from water efficiently using a catalytic technique powered by sunlight – a process that is part of photosynthesis and so effective that it is the Earth's major source of oxygen.
Biochemistry
Source: Georgia Institute of Technology Research News
Posted on: Tuesday, Apr 03, 2012, 12:45pm
Rating: | Views: 1377 | Comments: 0
Source: Georgia Institute of Technology Research News
Posted on: Tuesday, Apr 03, 2012, 12:45pm
Rating: | Views: 1377 | Comments: 0
Study reveals insight into how key protein protects against viral infections
Scientists from the University of Utah School of Medicine have discovered that a mouse protein called IFITM3 contributes to the body's defense against some types of viral infections by binding to an enzyme responsible for regulating the pH of a cell's waste disposal system. This finding, published in the March 30, 2012, issue of Innate Immunity, sheds light on the cellular
Scientists from the University of Utah School of Medicine have discovered that a mouse protein called IFITM3 contributes to the body's defense against some types of viral infections by binding to an enzyme responsible for regulating the pH of a cell's waste disposal system. This finding, published in the March 30, 2012, issue of Innate Immunity, sheds light on the cellular
Biochemistry
Source: University of Utah Health Sciences
Posted on: Monday, Apr 02, 2012, 1:30pm
Rating: | Views: 1130 | Comments: 0
Source: University of Utah Health Sciences
Posted on: Monday, Apr 02, 2012, 1:30pm
Rating: | Views: 1130 | Comments: 0
Map of substrate-kinase interactions may lead to more effective cancer drugs
Later-stage cancers thrive by finding detours around roadblocks that cancer drugs put in their path, but a Purdue University biochemist is creating maps that will help drugmakers close more routes and develop better drugs.
Later-stage cancers thrive by finding detours around roadblocks that cancer drugs put in their path, but a Purdue University biochemist is creating maps that will help drugmakers close more routes and develop better drugs.
Biochemistry
Source: Purdue University
Posted on: Wednesday, Mar 28, 2012, 10:15am
Rating: | Views: 1096 | Comments: 0
Source: Purdue University
Posted on: Wednesday, Mar 28, 2012, 10:15am
Rating: | Views: 1096 | Comments: 0
Vitamins doing gymnastics: Scientists capture first full image of vitamin B12 in action
You see it listed on the side of your cereal box and your multivitamin bottle. It's vitamin B12, part of a nutritious diet like all those other vitamins and minerals.
You see it listed on the side of your cereal box and your multivitamin bottle. It's vitamin B12, part of a nutritious diet like all those other vitamins and minerals.
Biochemistry
Source: University of Michigan Health System
Posted on: Tuesday, Mar 27, 2012, 12:45pm
Rating: | Views: 1391 | Comments: 0
Source: University of Michigan Health System
Posted on: Tuesday, Mar 27, 2012, 12:45pm
Rating: | Views: 1391 | Comments: 0
Discovery offers insight into treating viral stomach flu
Twenty million Americans get sick from norovirus each year according to data released last week by the Centers for Disease Control (CDC). Often called vomiting illness, it can spread rapidly on cruise ships, and in dormitories and hospitals. Recent data from the CDC shows deaths from gastrointestinal infections have more than doubled and have become a particular th
Twenty million Americans get sick from norovirus each year according to data released last week by the Centers for Disease Control (CDC). Often called vomiting illness, it can spread rapidly on cruise ships, and in dormitories and hospitals. Recent data from the CDC shows deaths from gastrointestinal infections have more than doubled and have become a particular th
Biochemistry
Source: Donald Danforth Plant Science Center
Posted on: Thursday, Mar 22, 2012, 1:00pm
Rating: | Views: 1350 | Comments: 0
Source: Donald Danforth Plant Science Center
Posted on: Thursday, Mar 22, 2012, 1:00pm
Rating: | Views: 1350 | Comments: 0
Structure of 'Salvia' receptor solved
At the molecular level, drugs like salvinorin A (the active ingredient of the hallucinogenic plant Salvia divinorum) work by activating specific proteins, known as receptors, in the brain and body.
At the molecular level, drugs like salvinorin A (the active ingredient of the hallucinogenic plant Salvia divinorum) work by activating specific proteins, known as receptors, in the brain and body.
Biochemistry
Source: University of North Carolina School of Medicine
Posted on: Thursday, Mar 22, 2012, 12:00pm
Rating: | Views: 1347 | Comments: 0
Source: University of North Carolina School of Medicine
Posted on: Thursday, Mar 22, 2012, 12:00pm
Rating: | Views: 1347 | Comments: 0
Proteins shine a brighter light on cellular processes
Scientists have designed a molecule which, in living cells, emits turquoise light three times brighter than possible until recently. This improves the sensitivity of cellular imaging, a technique where biological processes inside a living organism are imaged at high resolution. The results have been published in Nature Communications on 20 March 2012.
Scientists have designed a molecule which, in living cells, emits turquoise light three times brighter than possible until recently. This improves the sensitivity of cellular imaging, a technique where biological processes inside a living organism are imaged at high resolution. The results have been published in Nature Communications on 20 March 2012.
Biochemistry
Source: European Synchrotron Radiation Facility
Posted on: Wednesday, Mar 21, 2012, 11:15am
Rating: | Views: 1148 | Comments: 0
Source: European Synchrotron Radiation Facility
Posted on: Wednesday, Mar 21, 2012, 11:15am
Rating: | Views: 1148 | Comments: 0
Study suggests link between H. pylori bacteria and adult Type 2 diabetes
A recent study shows that the presence of H. pylori bacteria is associated with elevated levels of glycosylated hemoglobin (HbA1c), an important biomarker for blood glucose levels and diabetes. This association was stronger in obese individuals with a higher Body Mass Index (BMI). The results, which suggest the bacteria may play a role in the development of di
A recent study shows that the presence of H. pylori bacteria is associated with elevated levels of glycosylated hemoglobin (HbA1c), an important biomarker for blood glucose levels and diabetes. This association was stronger in obese individuals with a higher Body Mass Index (BMI). The results, which suggest the bacteria may play a role in the development of di
Biochemistry
Source: Infectious Diseases Society of America
Posted on: Wednesday, Mar 14, 2012, 12:30pm
Rating: | Views: 1242 | Comments: 0
Source: Infectious Diseases Society of America
Posted on: Wednesday, Mar 14, 2012, 12:30pm
Rating: | Views: 1242 | Comments: 0
Study of ribosome evolution challenges 'RNA World' hypothesis
In the beginning – of the ribosome, the cell's protein-building workbench – there were ribonucleic acids, the molecules we call RNA that today perform a host of vital functions in cells. And according to a new analysis, even before the ribosome's many working parts were recruited for protein synthesis, proteins also were on the scene and interacting with RNA. This finding challen
In the beginning – of the ribosome, the cell's protein-building workbench – there were ribonucleic acids, the molecules we call RNA that today perform a host of vital functions in cells. And according to a new analysis, even before the ribosome's many working parts were recruited for protein synthesis, proteins also were on the scene and interacting with RNA. This finding challen
Biochemistry
Source: University of Illinois at Urbana-Champaign
Posted on: Tuesday, Mar 13, 2012, 10:00am
Rating: | Views: 1255 | Comments: 0
Source: University of Illinois at Urbana-Champaign
Posted on: Tuesday, Mar 13, 2012, 10:00am
Rating: | Views: 1255 | Comments: 0
Correcting human mitochondrial mutations
Researchers at the UCLA stem cell center and the departments of chemistry and biochemistry and pathology and laboratory medicine have identified, for the first time, a generic way to correct mutations in human mitochondrial DNA by targeting corrective RNAs, a finding with implications for treating a host of mitochondrial diseases.
Researchers at the UCLA stem cell center and the departments of chemistry and biochemistry and pathology and laboratory medicine have identified, for the first time, a generic way to correct mutations in human mitochondrial DNA by targeting corrective RNAs, a finding with implications for treating a host of mitochondrial diseases.
Agriculture
Source: University of California - Los Angeles Health Sciences
Posted on: Monday, Mar 12, 2012, 4:15pm
Rating: | Views: 1357 | Comments: 0
Source: University of California - Los Angeles Health Sciences
Posted on: Monday, Mar 12, 2012, 4:15pm
Rating: | Views: 1357 | Comments: 0
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