Binding sites for LIN28 protein found in thousands of human genes A study led by researchers at the UC San Diego Stem Cell Research program and funded by the California Institute for Regenerative Medicine (CIRM) looks at an important RNA binding protein called LIN28, which is implicated in pluripotency and reprogramming as well as in cancer and other diseases. According to the researchers, their study – published in the September 6 online issue of Molecular
Biochemistry Source: University of California - San Diego
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Wednesday, Sep 05, 2012, 10:30am Rating: | Views: 1204 | Comments: 0
Researchers discover missing link between stem cells and immune system UCLA researchers have discovered a type of cell that is the "missing link" between bone marrow stem cells and all the cells of the human immune system, a finding that will lead to a greater understanding of how a healthy immune system is produced and how disease can lead to poor immune function.
Immunology Source: University of California - Los Angeles Health Sciences
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Tuesday, Sep 04, 2012, 10:45am Rating: | Views: 1324 | Comments: 0
Stem cells Source: University of Michigan Health System
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Wednesday, Aug 22, 2012, 8:30am Rating: | Views: 1208 | Comments: 0
Stem cell therapy shows promise in repairing stress urinary incontinence Stress urinary incontinence (SUI) can occur due to sneezing, coughing, exercising or even laughing and happens because the pelvic floor muscles are too weak causing leakage when the bladder is put under pressure. New research published in BioMed Central's open access journal BMC Medicine shows that a new technique, using stem cells isolated from amniotic fluid, can regenerate damaged urethr
Health Source: BioMed Central
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Tuesday, Aug 21, 2012, 12:00pm Rating: | Views: 1277 | Comments: 0
B cell survival holds key to chronic graft vs. host disease Leukemia and lymphoma patients who receive life-saving stem cell or bone marrow transplants often experience chronic side effects that significantly decrease quality of life, can last a lifetime, and ultimately affect their long-term survival.
Immunology Source: University of North Carolina Health Care
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Friday, Aug 17, 2012, 10:30am Rating: | Views: 1223 | Comments: 0
Stem cells Source: Duke University Medical Center
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Monday, Aug 13, 2012, 11:15am Rating: | Views: 1200 | Comments: 0
Research shows how protein component that enables cell replication gets ferried to chromosome tips Stem cells are special. Nestled in muscle and skin, organ and bone, they bide their time over years or decades until called to replace damaged or lost tissue. One secret to their longevity is an enzyme called telomerase, which stills the relentless ticking of the molecular clock that limits the life span of other cells.
Molecular Biology Source: Stanford University Medical Center
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Friday, Aug 03, 2012, 11:30am Rating: | Views: 1141 | Comments: 0
A drug-screening platform for ALS A research group at the Center for iPS Cell Research and Application (CiRA) at Japan's Kyoto University has successfully recapitulated amyotrophic lateral sclerosis (ALS)-associated abnormalities in motor neurons differentiated from induced pluripotent stem cells (iPSCs) obtained from patients with familial ALS, a late-onset, fatal disorder which is also known for Lou
Neuroscience Source: Center for iPS Cell Research and Application - Kyoto University
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Friday, Aug 03, 2012, 8:15am Rating: | Views: 1214 | Comments: 0
Researchers find driver of breast cancer stem cell metastasis Researchers at the University of Michigan Comprehensive Cancer Center have found that a cancer gene linked to aggressive spread of the disease promotes breast cancer stem cells. The finding implies a new way to target the behavior of these lethal cells.
Cancer Source: University of Michigan Health System
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Wednesday, Jul 25, 2012, 11:00am Rating: | Views: 1140 | Comments: 0
The Yin and Yang of stem cell quiescence and proliferation Not all adult stem cells are created equal. Some are busy regenerating worn out or damaged tissues, while their quieter brethren serve as a strategic back-up crew that only steps in when demand shoots up. Now, researchers at the Stowers Institute for Medical Research have identified an important molecular cue that keeps quiescent mouse hematopoietic (or blood-forming) stem cells fr
Molecular Biology Source: Stowers Institute for Medical Research
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Friday, Jul 20, 2012, 11:45am Rating: | Views: 1253 | Comments: 0
Researchers identify mechanisms that allow embryonic stem cells to become any cell in the human body New research at the Hebrew University of Jerusalem sheds light on pluripotency—the ability of embryonic stem cells to renew themselves indefinitely and to differentiate into all types of mature cells. Solving this problem, which is a major challenge in modern biology, could expedite the use of embryonic stem cells in cell therapy and regenerative medicine. If scientists can replicate the mechanism
Stem cells Source: The Hebrew University of Jerusalem
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Thursday, Jul 19, 2012, 10:15am Rating: | Views: 1143 | Comments: 0
Stem cells Source: University of California - Los Angeles
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Monday, Jul 09, 2012, 12:00pm Rating: | Views: 1216 | Comments: 0
The key (proteins) to self-renewing skin In the July 6 issue of Cell Stem Cell, researchers at the University of California, San Diego School of Medicine describe how human epidermal progenitor cells and stem cells control transcription factors to avoid premature differentiation, preserving their ability to produce new skin cells throughout life.
Stem cells Source: University of California - San Diego
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Friday, Jul 06, 2012, 11:30am Rating: | Views: 1147 | Comments: 0
Magnet helps target transplanted iron-loaded cells to key areas of heart Optimal stem cell therapy delivery to damaged areas of the heart after myocardial infarction has been hampered by inefficient homing of cells to the damaged site. However, using rat models, researchers in France have used a magnet to guide cells loaded with iron oxide nanoparticles to key sites, enhancing the myocardial retention of intravascularly delivered endothelial progenitor cells.
Health Source: Cell Transplantation Center of Excellence for Aging and Brain Repair
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Wednesday, Jun 27, 2012, 10:30am Rating: | Views: 1142 | Comments: 0
'Master molecule' may improve stem cell treatment of heart attacks Johns Hopkins researchers have discovered that a single protein molecule may hold the key to turning cardiac stem cells into blood vessels or muscle tissue, a finding that may lead to better ways to treat heart attack patients.
Stem cells Source: Johns Hopkins University
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Thursday, Jun 21, 2012, 1:00pm Rating: | Views: 1075 | Comments: 0
Scientists see new hope for restoring vision with stem cell help Human-derived stem cells can spontaneously form the tissue that develops into the part of the eye that allows us to see, according to a study published by Cell Press in the 5th anniversary issue of the journal Cell Stem Cell. Transplantation of this 3D tissue in the future could help patients with visual impairments see clearly.
Stem cells Source: Cell Press
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Thursday, Jun 14, 2012, 10:15am Rating: | Views: 1108 | Comments: 0
A better way to grow bone: Fresh, purified fat stem cells grow bone faster and better UCLA stem cell scientists purified a subset of stem cells found in fat tissue and made from them bone that was formed faster and was of higher quality than bone grown using traditional methods, a finding that may one day eliminate the need for painful bone grafts that use material taken from the patient during invasive procedures.
Stem cells Source: University of California - Los Angeles Health Sciences
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Monday, Jun 11, 2012, 11:45am Rating: | Views: 1231 | Comments: 0
Researcher identifies unusual 'altruistic' stem cell behavior with possible link to cancer When most groups of mammalian cells are faced with a shortage of nutrients or oxygen, the phrase "every man for himself" is more apt than "all for one, one for all." Unlike colonies of bacteria, which often cooperate to thrive as a group, mammalian cells have never been observed to help one another out. But a new study led by a researcher at the Stanford University School of Med
Stem cells Source: Stanford University Medical Center
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Monday, Jun 11, 2012, 11:30am Rating: | Views: 1136 | Comments: 0
Drug bans hamper brain research, says neuroscientist Bans on drugs like ecstasy, magic mushrooms and LSD have hampered scientific research on the brain and stalled the progress of medicine as much as George Bush's ban on stem cell research did, a leading British drug expert said on Thursday.
Neuroscience Source: Reuters
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Thursday, May 31, 2012, 9:05am Rating: | Views: 1094 | Comments: 0
Health Source: University of Wisconsin-Madison
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Tuesday, May 29, 2012, 2:00pm Rating: | Views: 1400 | Comments: 0
Stem-cell-growing surface enables bone repair University of Michigan researchers have proven that a special surface, free of biological contaminants, allows adult-derived stem cells to thrive and transform into multiple cell types. Their success brings stem cell therapies another step closer.
Stem cells Source: University of Michigan
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Thursday, May 24, 2012, 12:15pm Rating: | Views: 1125 | Comments: 0
Treating pain with transplants A new study finds that transplanting embryonic cells into adult mouse spinal cord can alleviate persistent pain. The research, published by Cell Press in the May 24th issue of the journal Neuron, suggests that reduced pain results from successful integration of the embryonic cells into the host spinal cord. The findings open avenues for clinical strategies aimed not just at treating the sym
Stem cells Source: Cell Press
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Thursday, May 24, 2012, 10:15am Rating: | Views: 1070 | Comments: 0
Gene-modified stem cell transplant protects patients from toxic side effects of chemotherapy For the first time, scientists at Fred Hutchinson Cancer Research Center have transplanted brain cancer patients' own gene-modified blood stem cells in order to protect their bone marrow against the toxic side effects of chemotherapy. Initial results of the ongoing, small clinical trial of three patients with glioblastoma showed that two patients survived longer than predicted if they
Cancer Source: Fred Hutchinson Cancer Research Center
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Thursday, May 10, 2012, 12:30pm Rating: | Views: 1234 | Comments: 0
Scientists measure communication between stem cell-derived motor neurons and muscle cells In an effort to identify the underlying causes of neurological disorders that impair motor functions such as walking and breathing, UCLA researchers have developed a novel system to measure the communication between stem cell-derived motor neurons and muscle cells in a Petri dish.
Neuroscience Source: University of California - Los Angeles Health Sciences
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Monday, May 07, 2012, 10:30am Rating: | Views: 1307 | Comments: 0
A single stem cell mutation triggers fibroid tumors Fibroid uterine tumors affect an estimated 15 million women in the United States, causing irregular bleeding, anemia, pain and infertility. Despite the high prevalence of the tumors, which occur in 60 percent of women by age 45, the molecular cause has been unknown.
Cancer Source: Northwestern University
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Monday, May 07, 2012, 10:00am Rating: | Views: 1102 | Comments: 0