News Archive Search
Video: Moving cells with light holds medical promise 
Scientists at Washington University School of Medicine in St. Louis have shown they can coax cells to move toward a beam of light. The feat is a first step toward manipulating cells to control insulin secretion or heart rate using light.
Scientists at Washington University School of Medicine in St. Louis have shown they can coax cells to move toward a beam of light. The feat is a first step toward manipulating cells to control insulin secretion or heart rate using light.
Molecular Biology
Source: Washington University School of Medicine
Posted on: Tuesday, Apr 09, 2013, 11:45am
Rating: | Views: 1772 | Comments: 0
Source: Washington University School of Medicine
Posted on: Tuesday, Apr 09, 2013, 11:45am
Rating: | Views: 1772 | Comments: 0
Mitochondrial metabolic regulator SIRT4 guards against DNA damage
Healthy cells don't just happen. As they grow and divide, they need checks and balances to ensure they function properly while adapting to changing conditions around them.
Healthy cells don't just happen. As they grow and divide, they need checks and balances to ensure they function properly while adapting to changing conditions around them.
Molecular Biology
Source: Harvard Medical School
Posted on: Friday, Apr 05, 2013, 1:45pm
Rating: | Views: 1876 | Comments: 0
Source: Harvard Medical School
Posted on: Friday, Apr 05, 2013, 1:45pm
Rating: | Views: 1876 | Comments: 0
Shutting down DNA construction: How senescence halts growth of potential cancers
Researchers from The Wistar Institute explain a new molecular mechanism behind the phenomenon of oncogene-induced senescence. By depriving the cell of the ability to make new nucleotides—the building blocks of DNA molecules—cells can suppress cancer development by forcing a damaged cell into a senescent state, where the cell remains alive yet cannot reproduce. According to the researchers, th
Researchers from The Wistar Institute explain a new molecular mechanism behind the phenomenon of oncogene-induced senescence. By depriving the cell of the ability to make new nucleotides—the building blocks of DNA molecules—cells can suppress cancer development by forcing a damaged cell into a senescent state, where the cell remains alive yet cannot reproduce. According to the researchers, th
Cancer
Source: The Wistar Institute
Posted on: Friday, Apr 05, 2013, 12:45pm
Rating: | Views: 3031 | Comments: 0
Source: The Wistar Institute
Posted on: Friday, Apr 05, 2013, 12:45pm
Rating: | Views: 3031 | Comments: 0
Protein maintains order in the nucleus
Two metres of DNA are packed into the cell nucleus, presumably based on a strictly defined arrangement. Researchers working with biologist Patrick Heun from the Max Planck Institute of Immunobiology and Epigenetics in Freiburg have now succeeded in explaining a phenomenon, which was first observed 40 years ago.
Two metres of DNA are packed into the cell nucleus, presumably based on a strictly defined arrangement. Researchers working with biologist Patrick Heun from the Max Planck Institute of Immunobiology and Epigenetics in Freiburg have now succeeded in explaining a phenomenon, which was first observed 40 years ago.
Molecular Biology
Source: Max-Planck-Gesellschaft
Posted on: Friday, Apr 05, 2013, 12:30pm
Rating: | Views: 1428 | Comments: 0
Source: Max-Planck-Gesellschaft
Posted on: Friday, Apr 05, 2013, 12:30pm
Rating: | Views: 1428 | Comments: 0
Accused of complicity in Alzheimer's, amyloid proteins may be getting a bad rap
Amyloids — clumps of misfolded proteins found in the brains of people with Alzheimer's disease and other neurodegenerative disorders — are the quintessential bad boys of neurobiology. They're thought to muck up the seamless workings of the neurons responsible for memory and movement, and researchers around the world have devoted themselves to devising ways of blocking their prod
Amyloids — clumps of misfolded proteins found in the brains of people with Alzheimer's disease and other neurodegenerative disorders — are the quintessential bad boys of neurobiology. They're thought to muck up the seamless workings of the neurons responsible for memory and movement, and researchers around the world have devoted themselves to devising ways of blocking their prod
Molecular Biology
Source: Stanford University Medical Center
Posted on: Thursday, Apr 04, 2013, 11:00am
Rating: | Views: 1480 | Comments: 0
Source: Stanford University Medical Center
Posted on: Thursday, Apr 04, 2013, 11:00am
Rating: | Views: 1480 | Comments: 0
Autism linked to increased genetic change in regions of genome instability
Children with autism have increased levels of genetic change in regions of the genome prone to DNA rearrangements, so called "hotspots," according to a research discovery to be published in the print edition of the journal Human Molecular Genetics. The research indicates that these genetic changes come in the form of an excess of duplicated DNA segments in hotspot regions and may affect the
Children with autism have increased levels of genetic change in regions of the genome prone to DNA rearrangements, so called "hotspots," according to a research discovery to be published in the print edition of the journal Human Molecular Genetics. The research indicates that these genetic changes come in the form of an excess of duplicated DNA segments in hotspot regions and may affect the
Genetics
Source: Penn State
Posted on: Wednesday, Apr 03, 2013, 2:00pm
Rating: | Views: 1454 | Comments: 0
Source: Penn State
Posted on: Wednesday, Apr 03, 2013, 2:00pm
Rating: | Views: 1454 | Comments: 0
Research reveals how antibodies neutralize mosquito-borne virus
Researchers have learned the precise structure of the mosquito-transmitted chikungunya virus pathogen while it is bound to antibodies, showing how the infection is likely neutralized.
Researchers have learned the precise structure of the mosquito-transmitted chikungunya virus pathogen while it is bound to antibodies, showing how the infection is likely neutralized.
Molecular Biology
Source: Purdue University
Posted on: Wednesday, Apr 03, 2013, 11:00am
Rating: | Views: 1730 | Comments: 0
Source: Purdue University
Posted on: Wednesday, Apr 03, 2013, 11:00am
Rating: | Views: 1730 | Comments: 0
How the worm turns
New research by scientists at the University of Massachusetts Medical School shows at the single cell level how an external stimulus sets off a molecular chain reaction in the transparent roundworm C. elegans, a process in which a single neurotransmitter coordinates and times two separate actions. These findings shed new light on how neurons translate sensory input into act
New research by scientists at the University of Massachusetts Medical School shows at the single cell level how an external stimulus sets off a molecular chain reaction in the transparent roundworm C. elegans, a process in which a single neurotransmitter coordinates and times two separate actions. These findings shed new light on how neurons translate sensory input into act
Neuroscience
Source: University of Massachusetts Medical School
Posted on: Wednesday, Apr 03, 2013, 10:30am
Rating: | Views: 1295 | Comments: 0
Source: University of Massachusetts Medical School
Posted on: Wednesday, Apr 03, 2013, 10:30am
Rating: | Views: 1295 | Comments: 0
Crucial step in human DNA replication observed for the first time
For the first time, an elusive step in the process of human DNA replication has been demystified by scientists at Penn State University. According to senior author Stephen J. Benkovic, an Evan Pugh Professor of Chemistry and Holder of the Eberly Family Chair in Chemistry at Penn State, the scientists "discovered how a key step in human DNA replication is performed." The results of the research wil
For the first time, an elusive step in the process of human DNA replication has been demystified by scientists at Penn State University. According to senior author Stephen J. Benkovic, an Evan Pugh Professor of Chemistry and Holder of the Eberly Family Chair in Chemistry at Penn State, the scientists "discovered how a key step in human DNA replication is performed." The results of the research wil
Molecular Biology
Source: Penn State
Posted on: Tuesday, Apr 02, 2013, 11:45am
Rating: | Views: 2301 | Comments: 0
Source: Penn State
Posted on: Tuesday, Apr 02, 2013, 11:45am
Rating: | Views: 2301 | Comments: 0
Mechanism of mutant histone protein in childhood brain cancer revealed
Most cancer treatments are blunt. In an attempt to eradicate tumors, oncologists often turn to radiation or chemotherapy, which can damage healthy tissue along with the cancerous growths. New research from C. David Allis' laboratory at Rockefeller University may bring scientists closer to designing cancer therapeutics that can target tumors with pinpoint accuracy.
Most cancer treatments are blunt. In an attempt to eradicate tumors, oncologists often turn to radiation or chemotherapy, which can damage healthy tissue along with the cancerous growths. New research from C. David Allis' laboratory at Rockefeller University may bring scientists closer to designing cancer therapeutics that can target tumors with pinpoint accuracy.
Molecular Biology
Source: Rockefeller University
Posted on: Tuesday, Apr 02, 2013, 11:00am
Rating: | Views: 1545 | Comments: 0
Source: Rockefeller University
Posted on: Tuesday, Apr 02, 2013, 11:00am
Rating: | Views: 1545 | Comments: 0
DNA: How to unravel the tangle
A research coordinated by the scientists at SISSA of Trieste has now developed and studied a numeric model of the chromosome that supports the experimental data and provides a hypothesis on the bundle's function.
A research coordinated by the scientists at SISSA of Trieste has now developed and studied a numeric model of the chromosome that supports the experimental data and provides a hypothesis on the bundle's function.
Molecular Biology
Source: International School of Advanced Studies (SISSA)
Posted on: Monday, Apr 01, 2013, 11:45am
Rating: | Views: 1559 | Comments: 0
Source: International School of Advanced Studies (SISSA)
Posted on: Monday, Apr 01, 2013, 11:45am
Rating: | Views: 1559 | Comments: 0
Head-on collisions between DNA-code reading machineries accelerate gene evolution
Bacteria appear to speed up their evolution by positioning specific genes along the route of expected traffic jams in DNA encoding. Certain genes are in prime collision paths for the moving molecular machineries that read the DNA code, as University of Washington scientists explain in this week's edition of Nature.
Bacteria appear to speed up their evolution by positioning specific genes along the route of expected traffic jams in DNA encoding. Certain genes are in prime collision paths for the moving molecular machineries that read the DNA code, as University of Washington scientists explain in this week's edition of Nature.
Molecular Biology
Source: University of Washington
Posted on: Monday, Apr 01, 2013, 10:00am
Rating: | Views: 1614 | Comments: 0
Source: University of Washington
Posted on: Monday, Apr 01, 2013, 10:00am
Rating: | Views: 1614 | Comments: 0
Cell reprogramming during liver regeneration
During embryonic development, animals generate many different types of cells, each with a distinct function and identity.
During embryonic development, animals generate many different types of cells, each with a distinct function and identity.
Molecular Biology
Source: University of Pennsylvania School of Medicine
Posted on: Friday, Mar 29, 2013, 1:30pm
Rating: | Views: 2567 | Comments: 0
Source: University of Pennsylvania School of Medicine
Posted on: Friday, Mar 29, 2013, 1:30pm
Rating: | Views: 2567 | Comments: 0
Researchers show stem cell fate depends on 'grip'
The field of regenerative medicine holds great promise, propelled by greater understanding of how stem cells differentiate themselves into many of the body's different cell types. But clinical applications in the field have been slow to materialize, partially owing to difficulties in replicating the conditions these cells naturally experience.
The field of regenerative medicine holds great promise, propelled by greater understanding of how stem cells differentiate themselves into many of the body's different cell types. But clinical applications in the field have been slow to materialize, partially owing to difficulties in replicating the conditions these cells naturally experience.
Molecular Biology
Source: University of Pennsylvania
Posted on: Friday, Mar 29, 2013, 1:15pm
Rating: | Views: 1591 | Comments: 0
Source: University of Pennsylvania
Posted on: Friday, Mar 29, 2013, 1:15pm
Rating: | Views: 1591 | Comments: 0
Parkinson's disease protein gums up garbage disposal system in cells
Clumps of α-synuclein protein in nerve cells are hallmarks of many degenerative brain diseases, most notably Parkinson's disease.
Clumps of α-synuclein protein in nerve cells are hallmarks of many degenerative brain diseases, most notably Parkinson's disease.
Molecular Biology
Source: University of Pennsylvania School of Medicine
Posted on: Friday, Mar 29, 2013, 12:00pm
Rating: | Views: 1618 | Comments: 0
Source: University of Pennsylvania School of Medicine
Posted on: Friday, Mar 29, 2013, 12:00pm
Rating: | Views: 1618 | Comments: 0
Protective prion keeps yeast cells from going it alone
Most commonly associated with such maladies as "mad cow disease" and Creutzfeldt-Jakob disease, prions are increasingly recognized for their ability to induce potentially beneficial traits in a variety of organisms, yeast chief among them.
Most commonly associated with such maladies as "mad cow disease" and Creutzfeldt-Jakob disease, prions are increasingly recognized for their ability to induce potentially beneficial traits in a variety of organisms, yeast chief among them.
Molecular Biology
Source: Whitehead Institute for Biomedical Research
Posted on: Friday, Mar 29, 2013, 11:15am
Rating: | Views: 1548 | Comments: 0
Source: Whitehead Institute for Biomedical Research
Posted on: Friday, Mar 29, 2013, 11:15am
Rating: | Views: 1548 | Comments: 0
Biological transistor enables computing within living cells
When Charles Babbage prototyped the first computing machine in the 19th century, he imagined using mechanical gears and latches to control information. ENIAC, the first modern computer developed in the 1940s, used vacuum tubes and electricity. Today, computers use transistors made from highly engineered semiconducting materials to carry out their logical operations.
When Charles Babbage prototyped the first computing machine in the 19th century, he imagined using mechanical gears and latches to control information. ENIAC, the first modern computer developed in the 1940s, used vacuum tubes and electricity. Today, computers use transistors made from highly engineered semiconducting materials to carry out their logical operations.
Molecular Biology
Source: Stanford University Medical Center
Posted on: Friday, Mar 29, 2013, 10:00am
Rating: | Views: 3118 | Comments: 0
Source: Stanford University Medical Center
Posted on: Friday, Mar 29, 2013, 10:00am
Rating: | Views: 3118 | Comments: 0
How herpesvirus invades nervous system
Northwestern Medicine scientists have identified a component of the herpesvirus that "hijacks" machinery inside human cells, allowing the virus to rapidly and successfully invade the nervous system upon initial exposure.
Northwestern Medicine scientists have identified a component of the herpesvirus that "hijacks" machinery inside human cells, allowing the virus to rapidly and successfully invade the nervous system upon initial exposure.
Molecular Biology
Source: Northwestern University
Posted on: Friday, Mar 29, 2013, 8:00am
Rating: | Views: 1675 | Comments: 0
Source: Northwestern University
Posted on: Friday, Mar 29, 2013, 8:00am
Rating: | Views: 1675 | Comments: 0
Compounds found that alter cell signaling, could lead to new breast cancer treatments
Using a broad spectrum of analytical tools, scientists from the Florida campus of The Scripps Research Institute (TSRI) have uncovered a class of novel compounds that can alter cell signaling activity, resulting in a variety of responses including a strong anti-inflammatory effect. These findings could lead to new strategies for treating diseases such as breast cancer
Using a broad spectrum of analytical tools, scientists from the Florida campus of The Scripps Research Institute (TSRI) have uncovered a class of novel compounds that can alter cell signaling activity, resulting in a variety of responses including a strong anti-inflammatory effect. These findings could lead to new strategies for treating diseases such as breast cancer
Molecular Biology
Source: Scripps Research Institute
Posted on: Wednesday, Mar 27, 2013, 8:45am
Rating: | Views: 1398 | Comments: 0
Source: Scripps Research Institute
Posted on: Wednesday, Mar 27, 2013, 8:45am
Rating: | Views: 1398 | Comments: 0
Cleverly designed vaccine blocks H5 avian influenza in models
Until now most experimental vaccines against the highly lethal H5N1 avian influenza virus have lacked effectiveness. But a new vaccine has proven highly effective against the virus when tested in both mice and ferrets. It is also effective against the H9 subtype of avian influenza. The research is published online ahead of print in the Journal of Virology.
Until now most experimental vaccines against the highly lethal H5N1 avian influenza virus have lacked effectiveness. But a new vaccine has proven highly effective against the virus when tested in both mice and ferrets. It is also effective against the H9 subtype of avian influenza. The research is published online ahead of print in the Journal of Virology.
Molecular Biology
Source: American Society for Microbiology
Posted on: Tuesday, Mar 26, 2013, 1:00pm
Rating: | Views: 1509 | Comments: 0
Source: American Society for Microbiology
Posted on: Tuesday, Mar 26, 2013, 1:00pm
Rating: | Views: 1509 | Comments: 0
Reversing blood and freshening it up
The blood of young and old people differs. In an article published recently in the scientific journal Blood, a research group at Lund University in Sweden explain how they have succeeded in rejuvenating the blood of mice by reversing, or re-programming, the stem cells that produce blood.
The blood of young and old people differs. In an article published recently in the scientific journal Blood, a research group at Lund University in Sweden explain how they have succeeded in rejuvenating the blood of mice by reversing, or re-programming, the stem cells that produce blood.
Molecular Biology
Source: Lund University
Posted on: Tuesday, Mar 26, 2013, 12:30pm
Rating: | Views: 1439 | Comments: 0
Source: Lund University
Posted on: Tuesday, Mar 26, 2013, 12:30pm
Rating: | Views: 1439 | Comments: 0
Study finds molecular 'signature' for rapidly increasing form of esophageal cancer
During the past 30 years, the number of patients with cancers that originate near the junction of the esophagus and stomach has increased approximately 600 percent in the United States. The first extensive probe of the DNA of these esophageal adenocarcinomas (EACs) has revealed that many share a distinctive mix-up of letters of the genetic code, and found more than 20 mutated genes that had not pr
During the past 30 years, the number of patients with cancers that originate near the junction of the esophagus and stomach has increased approximately 600 percent in the United States. The first extensive probe of the DNA of these esophageal adenocarcinomas (EACs) has revealed that many share a distinctive mix-up of letters of the genetic code, and found more than 20 mutated genes that had not pr
Genetics
Source: Dana-Farber Cancer Institute
Posted on: Monday, Mar 25, 2013, 12:15pm
Rating: | Views: 6373 | Comments: 0
Source: Dana-Farber Cancer Institute
Posted on: Monday, Mar 25, 2013, 12:15pm
Rating: | Views: 6373 | Comments: 0
Researchers unravel molecular roots of Down syndrome
What is it about the extra chromosome inherited in Down syndrome—chromosome 21—that alters brain and body development? Researchers at Sanford-Burnham Medical Research Institute (Sanford-Burnham) have new evidence that points to a protein called sorting nexin 27, or SNX27. SNX27 production is inhibited by a molecule encoded on chromosome 21. The study, published M
What is it about the extra chromosome inherited in Down syndrome—chromosome 21—that alters brain and body development? Researchers at Sanford-Burnham Medical Research Institute (Sanford-Burnham) have new evidence that points to a protein called sorting nexin 27, or SNX27. SNX27 production is inhibited by a molecule encoded on chromosome 21. The study, published M
Molecular Biology
Source: Sanford-Burnham Medical Research Institute
Posted on: Monday, Mar 25, 2013, 11:45am
Rating: | Views: 1492 | Comments: 0
Source: Sanford-Burnham Medical Research Institute
Posted on: Monday, Mar 25, 2013, 11:45am
Rating: | Views: 1492 | Comments: 0
Computer simulations yield clues to how cells interact with surroundings
Your cells are social butterflies. They constantly interact with their surroundings, taking in cues on when to divide and where to anchor themselves, among other critical tasks.
Your cells are social butterflies. They constantly interact with their surroundings, taking in cues on when to divide and where to anchor themselves, among other critical tasks.
Molecular Biology
Source: DOE/Lawrence Berkeley National Laboratory
Posted on: Monday, Mar 25, 2013, 8:45am
Rating: | Views: 1428 | Comments: 0
Source: DOE/Lawrence Berkeley National Laboratory
Posted on: Monday, Mar 25, 2013, 8:45am
Rating: | Views: 1428 | Comments: 0
Study reveals potential treatments for Ebola and a range of other deadly viruses
Illnesses caused by many of the world's most deadly viruses cannot be effectively treated with existing drugs or vaccines. A study published by Cell Press in the March 21 issue of the journal Chemistry & Biology has revealed several compounds that can inhibit multiple viruses, such as highly lethal Ebola virus, as well as pathogens responsible for rabies, mumps, and measles, opening up ne
Illnesses caused by many of the world's most deadly viruses cannot be effectively treated with existing drugs or vaccines. A study published by Cell Press in the March 21 issue of the journal Chemistry & Biology has revealed several compounds that can inhibit multiple viruses, such as highly lethal Ebola virus, as well as pathogens responsible for rabies, mumps, and measles, opening up ne
Molecular Biology
Source: Cell Press
Posted on: Friday, Mar 22, 2013, 10:15am
Rating: | Views: 1932 | Comments: 0
Source: Cell Press
Posted on: Friday, Mar 22, 2013, 10:15am
Rating: | Views: 1932 | Comments: 0
Tiny RNA molecule may have role in polycystic ovary syndrome, insulin resistance
A group of tiny RNA molecules with a big role in regulating gene expression also appear to have a role in causing insulin resistance in woman with polycystic ovary syndrome and, perhaps, in all women, researchers report.
A group of tiny RNA molecules with a big role in regulating gene expression also appear to have a role in causing insulin resistance in woman with polycystic ovary syndrome and, perhaps, in all women, researchers report.
Molecular Biology
Source: Medical College of Georgia at Georgia Regents University
Posted on: Wednesday, Mar 20, 2013, 12:15pm
Rating: | Views: 1554 | Comments: 0
Source: Medical College of Georgia at Georgia Regents University
Posted on: Wednesday, Mar 20, 2013, 12:15pm
Rating: | Views: 1554 | Comments: 0
Tenfold boost in ability to pinpoint proteins in cancer cells
Better diagnosis and treatment of cancer could hinge on the ability to better understand a single cell at its molecular level. New research offers a more comprehensive way of analyzing one cell's unique behavior, using an array of colors to show patterns that could indicate why a cell will or won't become cancerous.
Better diagnosis and treatment of cancer could hinge on the ability to better understand a single cell at its molecular level. New research offers a more comprehensive way of analyzing one cell's unique behavior, using an array of colors to show patterns that could indicate why a cell will or won't become cancerous.
Cancer
Source: University of Washington
Posted on: Wednesday, Mar 20, 2013, 10:45am
Rating: | Views: 1438 | Comments: 0
Source: University of Washington
Posted on: Wednesday, Mar 20, 2013, 10:45am
Rating: | Views: 1438 | Comments: 0
Discovery could yield treatment for cocaine addicts
Scientists have discovered a molecular process in the brain triggered by cocaine use that could provide a target for treatments to prevent or reverse addiction to the drug.
Scientists have discovered a molecular process in the brain triggered by cocaine use that could provide a target for treatments to prevent or reverse addiction to the drug.
Neuroscience
Source: Michigan State University
Posted on: Monday, Mar 18, 2013, 8:00am
Rating: | Views: 1384 | Comments: 0
Source: Michigan State University
Posted on: Monday, Mar 18, 2013, 8:00am
Rating: | Views: 1384 | Comments: 0
New structural insight into neurodegenerative disease
A research team from the Korea Advanced Institute of Science and Technology (KAIST) released their results on the structure and molecular details of the neurodegenerative disease-associated protein Ataxin-1. Mutations in Ataxin-1 cause the neurological disease, Spinocerebella Ataxia Type 1 (SCA1), which is characterized by a loss of muscular coordinati
A research team from the Korea Advanced Institute of Science and Technology (KAIST) released their results on the structure and molecular details of the neurodegenerative disease-associated protein Ataxin-1. Mutations in Ataxin-1 cause the neurological disease, Spinocerebella Ataxia Type 1 (SCA1), which is characterized by a loss of muscular coordinati
Neuroscience
Source: The Korea Advanced Institute of Science and Technology (KAIST)
Posted on: Friday, Mar 15, 2013, 10:45am
Rating: | Views: 1670 | Comments: 0
Source: The Korea Advanced Institute of Science and Technology (KAIST)
Posted on: Friday, Mar 15, 2013, 10:45am
Rating: | Views: 1670 | Comments: 0
X-ray laser allows scientists to take live snapshots of chemical reactions
An international team under the leadership of Hamburg scientists has observed a catalyst in action on the molecular level with the world's strongest X-ray laser. The study shows surprising details of a chemical reaction and opens up the possibility to see live pictures of these ultrafast processes. For the first time, scientists directly verified a state of transition in which the molecules hover
An international team under the leadership of Hamburg scientists has observed a catalyst in action on the molecular level with the world's strongest X-ray laser. The study shows surprising details of a chemical reaction and opens up the possibility to see live pictures of these ultrafast processes. For the first time, scientists directly verified a state of transition in which the molecules hover
Chemistry
Source: Deutsches Elektronen-Synchrotron DESY
Posted on: Friday, Mar 15, 2013, 10:30am
Rating: | Views: 1578 | Comments: 0
Source: Deutsches Elektronen-Synchrotron DESY
Posted on: Friday, Mar 15, 2013, 10:30am
Rating: | Views: 1578 | Comments: 0
 |
 |
Friends