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User Information
Post DocHomepage:
http://twitter.com/ncrouseAddress:660 S EuclidBox 8111St. Louis, MO 63112 USAPhone:
314-362-1151
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Education History
University of Missouri - St. Louis
St. Louis, MO USA
8/2004 - 5/2009
Degree:
PhD - Biochemistry
Description of Work:
Studied the role that the Alzheimer’s Disease (AD) protein, amyloid β (Aβ) plays in the recruitment and differentiation of monocytic cells from the periphery into the brain. Developed methods to study the transformation of monocytes into macrophages including cell adhesion assays, plate based receptor detection assays and phagocytosis assays. Utilized a variety of other techniques including standard sandwich ELISA, fluorescence, absorbance, spectroscopic based toxicity and metabolic assays, antibody neutralization assays, binding studies, fluorescent microscopy and competition assays.
St. Louis, MO USA
8/2004 - 5/2009
Degree:
PhD - Biochemistry
Description of Work:
Studied the role that the Alzheimer’s Disease (AD) protein, amyloid β (Aβ) plays in the recruitment and differentiation of monocytic cells from the periphery into the brain. Developed methods to study the transformation of monocytes into macrophages including cell adhesion assays, plate based receptor detection assays and phagocytosis assays. Utilized a variety of other techniques including standard sandwich ELISA, fluorescence, absorbance, spectroscopic based toxicity and metabolic assays, antibody neutralization assays, binding studies, fluorescent microscopy and competition assays.
Carthage College
Kenosha, WI USA
8/2000 - 5/2004
Degree:
BA - Chemistry
Kenosha, WI USA
8/2000 - 5/2004
Degree:
BA - Chemistry
Washington University School of Medicine
St. Louis, MO USA
1/2010 - 0/0
Degree:
Postdoctoral Research Associate
Description of Work:
Studying pediatric gliomas in the context of the tumor predisposition syndrome, Neurofibromatosis-1.
St. Louis, MO USA
1/2010 - 0/0
Degree:
Postdoctoral Research Associate
Description of Work:
Studying pediatric gliomas in the context of the tumor predisposition syndrome, Neurofibromatosis-1.
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Work History
Pfizer
Chesterfield, MO USA
5/2009 - 12/2009
Position:
In Vitro Biologist
Description of Work:
Served as a member of a small, interdisciplinary team studying glial cell biology, especially in the context of Multiple Sclerosis (MS).
Chesterfield, MO USA
5/2009 - 12/2009
Position:
In Vitro Biologist
Description of Work:
Served as a member of a small, interdisciplinary team studying glial cell biology, especially in the context of Multiple Sclerosis (MS).
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Publications
Crouse NR Ajit D Udan ML Nichols MR. 2009. Oligomeric amyloid-beta(1-42) induces THP-1 human monocyte adhesion and maturation..Brain Res.. 1254:109-19
Udan ML Ajit D Crouse NR Nichols MR. 2007. Toll-like receptors 2 and 4 mediate Abeta(1-42) activation of the innate immune response in a human monocytic cell line..J. Neurochem.. 104:524-33
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